Representative Publications----Institute of Biochemistry and Cell Biology, Shanghai Institute for Biological Sciences, CAS

Research

Haixiao Wang, Xiuzhen Huang, Jialing Mou, Enci Wang, Yan Li, Wenjuan Pu, Yao Xie, Xiaoling Guo, Lixing Wang, Maoping Chu, Bin Zhou, Chao Niu,Contribution of Gli1+ Adventitial Stem Cells to Smooth Muscle Cells in Atherosclerosis and Vascular Injury,Adv Sci.2025 Dec 3.
Yuanyong Huang, Yimei Sun, Hongyun Qi, Quanlong Jiang, Jialun Li, Mingzhi Chang, Xinyan Li, Lei Shu, Xiaoya Duan, Yiqin Wang, Kailun Fang, Hailei Mao, Mengmeng Han,A conserved H3K14ub-driven H3K9me3 for chromatin compartmentalization,Nature.2025 Oct. 15.
Zhini Zhu, Yaohui Li, Hao Xia, Chuanhui Yang, Zixuan Zhou, Yulin Chao, Qian Ba, Dianfan Li, Qianhui Qu,Molecular basis of prostaglandin E2 reuptake by organic anion transporter PGT,Nat Commun.2025 Dec 1.
Zhini Zhu, Yaohui Li, Hao Xia, Chuanhui Yang, Zixuan Zhou, Yulin Chao, Qian Ba, Dianfan Li, Qianhui Qu,Molecular basis of prostaglandin E2 reuptake by organic anion transporter PGT,Nat Commun.2025 Dec 1.
Xinyu Thomas Tang, Yiming Liam Liu, Yidi Augenstern Du, Shan Shan Wang, Bo O Zhou,Mapping the Tissue-of-Origins of Mesenchymal Stromal Cells in Injury Repair,Adv Sci.2025 Nov 27.
Hongyan Gao, Yating Wang, Yulin Zhao, Xianyue Jiao, Zihan Guo, Lei Zheng, Yichen Li, Yingchun Su, Zhenqi Wang, Jingwei Bai, Jun Yao, Frederic D Bushman, Sai Luo, Xinyang Song, Guanxiang Liang,Human gut prophage landscape identifies a prophage-mediated fucosylation mechanism alleviating colitis,Nat Commun.2025 Nov 22.
Zhaoheng Lin, Yuxiao Zheng, Yu Zhong, Hongyan Wang,Single-Cell Insights Into Macrophage Subtypes in Pulmonary Infections,Adv Sci.2025 Nov 21.
Zijian Wang, Peng Tao, Luonan Chen,Delayformer: Spatiotemporal Transformation for Predicting High-Dimensional Dynamics,Adv Sci.2025 Nov 21.
Yangfeng Hou, Cheng Kiu Ho, Binglin Lai, Jitao Liu, Lilin Li, Jinhai Lin, Hang Qu, Randolph H L Wong, Yu Nie, Qiurong Ding, Bin Zhou, Kathy O Lui,CD4+ Tregs Regulate Heart Growth and Regeneration Through MRG15/TIP60-Mediated Epigenomic Remodeling in Proliferating Cardiomyocytes,Circulation.2025 Nov 18.
Jun Xiao, Shuang Wang, Miao Jin, Bin Wei, Hongyan Wang,Cholesterol metabolism regulates macrophage function and inflammation-related diseases,Trends Cell Biol.2025 Nov 13.
Lili Han, Fengmin Zhang, Jujin Zhang, Xiaonan Li, Kunpeng Wang, Biao Liu, Jiawen Song, Xinyan Liu, Yun Qian, Kai Li, Yingnan Lei, Claudia Spits, Yi Chang, Chengle Zhuang, Zhen Yu, Yun Zhao, Jiayin Peng,Gli1 regulates fibro/adipogenic progenitor function through modulation of Ido1 in muscle regeneration,Int J Biol Sci.2025 Sep 29.
Lei Fan, Qi Tang, Yutong Wang, Hang Sun, Ge Li, Yi Yang, Huiying Zhu, Zhaoyuan Liu, He Wang, Hongyan Wang, Qing Jing, Christopher L Antos, Hui Xiao, Renchu Guan, Gang Pei, Florent Ginhoux, Zhigang Zhou, An Zeng,Injury-induced Clusterin+ cardiomyocytes suppress inflammation and promote regeneration in neonatal and adult hearts by reprogramming macrophages,Cell Stem Cell.2025 Nov 7.
Suhao Cao, Shaogang Wang, Xuan Xie, Xinyi Tan, Xinyu Hu, Fengxia Shao, Yanling Liu, Xu Zhang, Hong Cheng, Lei Diao, Lan Bao,KDM4A serves as an α-tubulin demethylase regulating microtubule polymerization and cell mitosis,Sci Adv.025 Oct 31.
Zihao Wang, Yizheng Zhang, Ting Guo, Ming He, Yingying Xu, Sonali Bhattacharjee, Robert A Martienssen, Jie Ren,Dcr1 senses R-loops for RNAPII termination at sites of replication stress and repair pathway choice,Mol Cell.2025 Oct 28.
Rui Luo, Yawei Song, Meichen Wang, Longhao Zou, Fangtai Jiao, Tiange Yang, Guangchuan Wang, Zhuoyi Liang, Wei Wu, Hai-Qiang Dai,HTGTS-TCR-Seq for Profiling of Mouse and Human T-Cell Receptor α and β Gene Rearrangements and Diversity,Adv Sci.2025 Oct 27.
Yan Sun, Haochen Yang, Qing Xu, Xingya Li, Jinxing Lou, Jianchun Duan, Jiachen Xu, Zhuqing Liu, Yong Xia, Zhicai Lin, Linlin Li, Dan Sun, Jiaguo Li, Tao Liu, Jun Guo, Wenfeng Xu, Weimin Zhu, Yi Liu, Boyang Sun, Jia Zhong, Lijie Rong, Qijun Qian, Chenqi Xu, Jie Wang,Anti-PD-1 Nanobody-Armored MSLN CAR-T Therapy for Malignant Mesothelioma: Preclinical and Clinical Studies,Adv Sci.2025 Oct 24.
Jinlong Suo, Duo Wang, Jinghui Wang, Xubin Yin, Xuye Hu, Rui Shao, Shuqin Chen, Shaokun Sun, Jingyi Feng, Lijun Wang, Heng Feng, Zhengda Li, Wulei Hou, Lei Zhang, Yong Chen, Xianyou Zheng, Zuoyun Wang, Weiguo Zou,Targeting VGLL4 maintains extracellular matrix homeostasis and mitigates osteoarthritis in a preclinical model,Nat Commun.2025 Oct 22.
Weiyun Li, Miao Jin, Hongye Li, Ruiyue Zhong, Zhaoheng Lin, Miao Shen, Hongyan Wang,Amino acid and cholesterol metabolism in innate immunity,Mol Cell.2025 Oct 16.
Jiaoyang Li, Zhizhou Xia, Bo Jiao, Zhitong Li, Donghe Li, Pengfei Xu, Yi Huang, Jiawei Nie, Yuqing Dan, Xu Huang, Lei Yan, Rui Zhang, Wei Huang, Xinru Wang, Shiyu Ji, Mofang Liu, Ping Liu, Ruibao Ren,Palmitoyltransferase ZDHHC19 regulates histone-to-protamine exchange during spermiogenesis in mice,Sci Adv.2025 Oct 17.
Zhenqian Zhang, Hengwei Jin, Zhicong Liu, Mengyang Shi, Mingjun Zhang, Wenjuan Pu, Jie Li, Xuekun Li, Daqing Ma, Qiang Shu, Bin Zhou,Pleural cavity macrophages promote lung tumor establishment through tissue invasion,Protein Cell.2025 Oct 16.

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