Representative Publications----Institute of Biochemistry and Cell Biology, Shanghai Institute for Biological Sciences, CAS

Research

Jie Yin,Lele Yang,Yangli Xie,Yan Liu,Sheng Li,Wenjun Yang,Bo Xu,Hongbin Ji,Lianghua Ding,Kun Wang,Gang Li,Lin Chen,Ping Hu,Dkk3 dependent transcriptional regulation controls age related skeletal muscle atrophy,Nat Commun2018 May 1
Derous, Davina and Mitchell, Sharon E and Green, Cara L and Wang, Yingchun and Han, Jing Dong J and Chen, Luonan and Promislow, Daniel EL and Lusseau, David and Speakman, John R and Douglas, Alex.,The effects of graded levels of calorie restriction: VII. Topological rearrangement of hypothalamic aging networks.,Aging
Xianlong Fang, Dongmei Yang, Hongping Luo, Shuai Wu, Wenjie Dong, Jing Xiao, Sujing Yuan, Aimin Ni, Kang-Jian Zhang, Xin-Yuan Liu, and Liang Chu,SNORD126 promotes HCC and CRC cell growth by activating the PI3K–AKT pathway through FGFR2,Journal of Molecular Cell Biology[Epub ahead of print]
Zeng L, Cai C, Li S, Wang W, Li Y1,, Chen J, Zhu X, Zeng YA.,Essential Roles of Cyclin Y-Like 1 and Cyclin Y in Dividing Wnt-Responsive Mammary Stem/Progenitor Cells.,PLoS Genet.12(5):e1006055
Xingxing Xu*, Yonghui Tao*, Xiaobo Gao*, Lei Zhang, Xufang Li, Weiguo Zou, Kangcheng Ruan, Feng Wang, Guo-liang Xu, Ronggui Hu.,A CRISPR-based approach for targeted DNA demethylation.,Citation: Cell Discovery2: 16009; doi:10.1038/celldisc.2016.9
Xiaolong Zhou,Longxia He,Lijia Yu,Yong Wang,Xijin Wang,Enduo Wang,Tao Yang.,Mutations in KARS cause early-onset hearing loss and leukoencepha lopathy: Potential pathogenic mechanism,Hum Mutat.
Zhanyu Ding, Zhenglin Fu, Cong Xu, Yifan Wang, Yanxing Wang, Junrui Li, Liangliang Kong, Jinhuan Chen, Na Li, Rongguang Zhang, Yao Cong.,High-resolution cryo-EM structure of the proteasome in complex with ADP-AlFx.,Cell Res2017,27:373-385
Yuhong Han,Yue Xiong,Xuanming Shi,Jiang Wu,Yun Zhao,Jin Jiang.,Regulation of Gli ciliary localization and Hedgehog signaling by the PY-NLS/karyopherin-β2 nuclear import system.,PLoS Biol2017,15:e2002063
Tengfei Ma,Yingjie Peng,Wei Huang,Yabing Liu,Jianping Ding,The β and γ subunits play distinct functional roles in the α2βγ heterotetramer of human NAD-dependent isocitrate dehydrogenase.,Sci Rep.2017,7:41882
Zheng D, Wang R, Ye T, Yu S, Hu H, Shen X, Li Y, Ji H, Sun Y, Chen H.,MET exon 14 skipping defines a unique molecular class of non-small cell lung cancer.,Oncotarget
Leixin Wei,Xiukun Wang,Suming Yang,Wen Yuan,Jinsong Li,Efficient generation of the mouse model with a defined point mutation through haploid cell-mediated gene-editing,J Genet Genomics.
Lin Fu, Hailong Wu, Steven Y. Cheng, Daming Gao, Lei Zhang, Yun Zhao,Set7 mediated Gli3 methylation plays a positive role in the activation of Sonic Hedgehog pathway in mammal.,eLifee15690
Bai M, Liang D, Wang Y, Li Q, Wu Y & Li Jinsong,Spermatogenic cell-specific gene mutation in mice via CRISPR-Cas9,Journal of Genetics and Genomics20;43(5):289-96
Huang D, Li X, Sun L, Huang P, Ying H, Wang H, Wu J*, Song H*,Regulation of Hippo signalling by p38 signalling,J Mol Cell Biol
Ling-Ling Chen,The biogenesis and emerging roles of circular RNAs,Nat Rev Mol Cell Biol17:205-211
Ling-Ling Chen,Linking Long Noncoding RNA Localization and Function,Trends Biochem Sci41:761-772
Shi Jiao,Jingmin Guan,Min Chen,Wenjia Wang,Chuanchuan Li,Yugong Wang,Yunfeng Cheng,Zhaocai Zhou,Targeting IRF3 as a YAP agonist therapy against gastric cancer,J Exp Med2018,Jan 16
Liucun Zhu,Fangchu Su,YaoChen Xu,Quan Zou.,Network-based method for mining novel HPV infection related genes using random walk with restart algorithm.,BBA-MOL BASIS DIS
Shi Jiao,Chuanchuan Li,Qian Hao,Haofei Miao,Lei Zhang,Lin Li,and？Zhaocai Zhoua,VGLL4 targets a TCF4-TEAD4 complex to coregulate Wnt？and？Hippo signalling in colorectal cancer.,Nat Commun2017,8:14058
Jingyao Zhao, Xufeng Chen, Guangrong Song, Jiali Zhang, Haifeng Liu and Xiaolong Liu,Uhrf1 controls the self-renewal versus differentiation of hematopoietic stem cells by epigenetically regulating the cell-division modes,Proc Natl Acad Sci U S A2017,114:E142-E151

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