Representative Publications----Institute of Biochemistry and Cell Biology, Shanghai Institute for Biological Sciences, CAS

Research

Chenhua Wang,Ludi Zhang,Zhen Sun,Xiang Yuan,Baihua Wu,Jin Cen,Lei Cui,Kun Zhang,Chun Li,Jingqi Wu,Yajing Shu,Wenbin Sun,Jing Wang,Lijian Hui,Dedifferentiation-associated inflammatory factors of long-term expanded human hepatocytes exacerbate their elimination by macrophages during liver engraftment,Hepatology2022 Mar 1.
Xiang Gao,Xukai Ma,Xiang Li,Guowei Li,Chuxiao Liu,Jun Zhang,Ying Wang,Jia Wei,Jia Chen,Lingling Chen,Li Yang,Knockout of circRNAs by base editing back-splice sites of circularized exons,Genome Biol2022 Jan 10.
Fan Zhang,Qiyu Zeng,Hao Xu,Aining Xu,Dianjia Liu,Ningzhe Li,Yi Chen,Yi Jin,Chunhui Xu,Changzhou Feng,Yuanliang Zhang,Dan Liu,Na Liu,Yinyin Xie,Shanhe Yu,Hao Yuan,Kai Xue,Jingyi Shi,Tingxi Liu, Pengfei Xu,Weili Zhao,Yi Zhou,Lan Wang,Qiuhua Huang,Zhu Chen,Saijuan Chen,Xiaolong Zhou,Xiaojian Sun,Selective and competitive functions of the AAR and UPR pathways in stress-induced angiogenesis,Cell Discov2021 Oct 26.
Yiao Jiang,Jiayin Peng,Jiawen Song,Juan He,Man Jiang,Jia Wang,Liya Ma,Yuang Wang,Moubin Lin,Hailong Wu,Zhao Zhang,Dong Gao,Yun Zhao,Loss of Hilnc prevents diet-induced hepatic steatosis through binding of IGF2BP2,Nat Metab2021 Nov 8.
Hui Sophie Shu,Yiming Liam Liu,Xinyu Thomas Tang,Xinyi Shirley Zhang,Bin Zhou,Weiguo Zou,Bo O.Zhou,Tracing the skeletal progenitor transition during postnatal bone formation,Cell Stem Cell2021 Sep 8.
Chunyan Yi,Xiaoyu Sun,Yixiao Lin,Chenjian Gu,Longfei Ding,Xiao Lu,Zhuo Yang,Yaguang Zhang,Liyan Ma,Wangpeng Gu,Aidong Qu,Xu Zhou,Xiuling Li,Jianqing Xu,Zhiyang Ling,Youhua Xie,Hongzhou Lu,Bing Sun,Comprehensive mapping of binding hot spots of SARS-CoV-2 RBD-specific neutralizing antibodies for tracking immune escape variants,Genome Med2021 Oct 14.
Wendong Weng,Xiuxiu Liu,Kathy O Lui,Bin Zhou,Harnessing orthogonal recombinases to decipher cell fate with enhanced precision,Trends Cell Biol2021 Oct 15.
Junhao Fu,Qing Li,Xiaoyu Liu,Tianxiang Tu,Xiujuan Lv,Xidi Yin,Jineng Lv,Zongming Song,Jia Qu,Jinwei Zhang,Jinsong Li,Feng Gu,Human cell based directed evolution of adenine base editors with improved efficiency,Nat Commun2021 Oct 8.
Xinxin Zhu,Na Yang,Yu Yang,Feiyang Yuan,Dandan Yu,Yu Zhang,Zhaoqian Shu,Ning Nan,Hong Hu,Xiaoyan Liu,She Chen,Liming Sun,Huayi Wang,Spontaneous necroptosis and autoinflammation are blocked by an inhibitory phosphorylation on MLKL during neonatal development,Cell Res2021 Nov 2.
Yajuan Zhang,Hua Yu,Jie Zhang,Hong Gao,Siyao Wang,Shuxian Li,Ping Wei,Ji Liang,Guanzhen Yu,Xiongjun Wang,Xinxiang Li,Dawei Li,Weiwei Yang,Cul4A-DDB1-mediated monoubiquitination of phosphoglycerate dehydrogenase promotes colorectal cancer metastasis via increased S-adenosylmethionine,J Clin Invest2021 Nov 1.
Chuxiao Liu,Lingling Chen,Expanded regulation of circular RNA translation,Mol Cell2021 Oct 21.
Rui Shao,Zhong Zhang,Zhan Xu,Huiling Ouyang,Lijun Wang,Hongwei Ouyang,Matthew Greenblatt,Xi Chen,Weiguo Zou,H3K36 methyltransferase NSD1 regulates chondrocyte differentiation for skeletal development and fracture repair,Bone Res2021 Jun 7.
Wei Zheng,Fan Li,Zhanyu Ding,Hao Liu,Lei Zhu,Cong Xu,Jiawei Li,Qi Gao,Yanxing Wang,Zhenglin Fu,Chao Peng,Xiumin Yan,Xueliang Zhu,Yao Cong,Distinct architecture and composition of mouse axonemal radial spoke head revealed by cryo-EM,Proc Natl Acad Sci USA2021 Jan 16.
Weifeng Guo,Shaowu Zhang,Yuehua Feng,Jing Liang,Tao Zeng,Luonan Chen,Network controllability-based algorithm to target personalized driver genes for discovering combinatorial drugs of individual patients,Nucleic Acids Res2021 Jan 12.
Huijie Zhao,Qingxia Chen,Fan Li,Lihong Cui,Lele Xie,Qiongping Huang,Xin Liang,Jun Zhou,Xiumin Yan,Xueliang Zhu,Fibrogranular materials function as organizers to ensure the fidelity of multiciliary assembly,Nat Commun2021 Feb 24.
Ximeng Han,Zhenqian,Lingjuan,Huan Zhu,Yan Li,Wenjuan Pu,Maoying Han,Huan Zhao,Kuo Liu,Yi Li,Xiuzhen Huang,Mingjun Zhang,Hengwei Jin,Zan Lv, Juan Tang,Jinjin Wang,Ruilin Sun,Jian Fei, Xueying Tian,Shengzhong Duan,Qingdong Wang,Lixin Wang,Ben He,Bin Zhou,A suite of new Dre-recombinase drivers markedly expands the ability to perform intersection genetic targeting,Cell Stem Cell2021 Feb 9.
Fei Li,Ming Han,Pengfei Dai,Wei Xu,Juan He,Xiaoting Tao,Yang Wu,Xinyuan Tong,Xinyi Xia,Wangxin Guo,Yunjiao Zhou,Yunguang Li,Yiqin Zhu,Xiaoyu Zhang, Zhuang Liu,Rebiguli Aji,Xia Cai,Yutang Li,Di Qu,Yu Chen,Shibo Jiang,Qiao Wang,Hongbin Ji,Youhua Xie,Yihua Sun,Lu Lu,Dong Gao,Distinct mechanisms for TMPRSS2 expression explain organ-specific inhibition of SARS-CoV-2 infection by enzalutamide,Nat Commun2021 Feb 8.
Yufei Han,Qian Zhuang,Bo Sun,Wenping Lv,Sheng Wang,Qingjie Xiao,Bin Pang,Youli Zhou,Fuxing Wang,Pengliang Chi,Qisheng Wang,Zhen Li,Lizhe Zhu,Fuping Li,Dong Deng,Yingchih Chiang,Zhenfei Li,Ruobing Ren,Crystal structure of steroid reductase SRD5A reveals conserved steroid reduction mechanism,Nat Commun2021 Jan 19.
Ling-Ling Chen,Ling-Ling Chen: Linking Long Noncoding RNA Processing and Function to RNA Biology,Trends Biochem Sci41:733-734
Siyang Leng,Huanfei Ma,Jürgen Kurths,Yingcheng Lai,Wei Lin,Kazuyuki Aihara,Luonan Chen,Partial cross mapping eliminates indirect causal influences,Nat Commun2020 May 26.

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