Representative Publications----Institute of Biochemistry and Cell Biology, Shanghai Institute for Biological Sciences, CAS

Research

Xinxin Zhu,Na Yang,Yu Yang,Feiyang Yuan,Dandan Yu,Yu Zhang,Zhaoqian Shu,Ning Nan,Hong Hu,Xiaoyan Liu,She Chen,Liming Sun,Huayi Wang,Spontaneous necroptosis and autoinflammation are blocked by an inhibitory phosphorylation on MLKL during neonatal development,Cell Res2021 Nov 2.
Yajuan Zhang,Hua Yu,Jie Zhang,Hong Gao,Siyao Wang,Shuxian Li,Ping Wei,Ji Liang,Guanzhen Yu,Xiongjun Wang,Xinxiang Li,Dawei Li,Weiwei Yang,Cul4A-DDB1-mediated monoubiquitination of phosphoglycerate dehydrogenase promotes colorectal cancer metastasis via increased S-adenosylmethionine,J Clin Invest2021 Nov 1.
Chuxiao Liu,Lingling Chen,Expanded regulation of circular RNA translation,Mol Cell2021 Oct 21.
Rui Shao,Zhong Zhang,Zhan Xu,Huiling Ouyang,Lijun Wang,Hongwei Ouyang,Matthew Greenblatt,Xi Chen,Weiguo Zou,H3K36 methyltransferase NSD1 regulates chondrocyte differentiation for skeletal development and fracture repair,Bone Res2021 Jun 7.
Wei Zheng,Fan Li,Zhanyu Ding,Hao Liu,Lei Zhu,Cong Xu,Jiawei Li,Qi Gao,Yanxing Wang,Zhenglin Fu,Chao Peng,Xiumin Yan,Xueliang Zhu,Yao Cong,Distinct architecture and composition of mouse axonemal radial spoke head revealed by cryo-EM,Proc Natl Acad Sci USA2021 Jan 16.
Weifeng Guo,Shaowu Zhang,Yuehua Feng,Jing Liang,Tao Zeng,Luonan Chen,Network controllability-based algorithm to target personalized driver genes for discovering combinatorial drugs of individual patients,Nucleic Acids Res2021 Jan 12.
Huijie Zhao,Qingxia Chen,Fan Li,Lihong Cui,Lele Xie,Qiongping Huang,Xin Liang,Jun Zhou,Xiumin Yan,Xueliang Zhu,Fibrogranular materials function as organizers to ensure the fidelity of multiciliary assembly,Nat Commun2021 Feb 24.
Ximeng Han,Zhenqian,Lingjuan,Huan Zhu,Yan Li,Wenjuan Pu,Maoying Han,Huan Zhao,Kuo Liu,Yi Li,Xiuzhen Huang,Mingjun Zhang,Hengwei Jin,Zan Lv, Juan Tang,Jinjin Wang,Ruilin Sun,Jian Fei, Xueying Tian,Shengzhong Duan,Qingdong Wang,Lixin Wang,Ben He,Bin Zhou,A suite of new Dre-recombinase drivers markedly expands the ability to perform intersection genetic targeting,Cell Stem Cell2021 Feb 9.
Fei Li,Ming Han,Pengfei Dai,Wei Xu,Juan He,Xiaoting Tao,Yang Wu,Xinyuan Tong,Xinyi Xia,Wangxin Guo,Yunjiao Zhou,Yunguang Li,Yiqin Zhu,Xiaoyu Zhang, Zhuang Liu,Rebiguli Aji,Xia Cai,Yutang Li,Di Qu,Yu Chen,Shibo Jiang,Qiao Wang,Hongbin Ji,Youhua Xie,Yihua Sun,Lu Lu,Dong Gao,Distinct mechanisms for TMPRSS2 expression explain organ-specific inhibition of SARS-CoV-2 infection by enzalutamide,Nat Commun2021 Feb 8.
Yufei Han,Qian Zhuang,Bo Sun,Wenping Lv,Sheng Wang,Qingjie Xiao,Bin Pang,Youli Zhou,Fuxing Wang,Pengliang Chi,Qisheng Wang,Zhen Li,Lizhe Zhu,Fuping Li,Dong Deng,Yingchih Chiang,Zhenfei Li,Ruobing Ren,Crystal structure of steroid reductase SRD5A reveals conserved steroid reduction mechanism,Nat Commun2021 Jan 19.
Ling-Ling Chen,Ling-Ling Chen: Linking Long Noncoding RNA Processing and Function to RNA Biology,Trends Biochem Sci41:733-734
Siyang Leng,Huanfei Ma,Jürgen Kurths,Yingcheng Lai,Wei Lin,Kazuyuki Aihara,Luonan Chen,Partial cross mapping eliminates indirect causal influences,Nat Commun2020 May 26.
Lin Fu, Hailong Wu, Steven Y Cheng, Daming Gao, Lei Zhang and Yun Zhao,Set7 mediated Gli3 methylation plays a positive role in the activation of Sonic Hedgehog pathway,elifeeLife.15690
ShiHui Wang,ChenYu Wu,YueBin Zhang,QingLu Zhong,Hao Sun,WenPeng Cao,GaoXiang Ge,GuoHui Li,X.Frank Zhang,JianFeng Chen,Integrin α4β7 switches its ligand specificity via distinct conformer-specific activation,J Cell Biol2018 May 22
Yin, J., Wan, B., Sarkar, J., Horvath, K., Wu, J., Chen, Y., Cheng, G., Wan, K., Chin, P., Lei, M., Liu, Y.,Dimerization of SLX4 contributes to functioning of the SLX4-nuclease complex,Nucleic Acids Res44(10): 4871-80
Rongkuan Hu, Huan Yan, Xiaoyan Fei, Haiyang Liu，Jiarui Wu,Modulation of glucose metabolism by a natural compound from Chloranthus japonicus via activation of AMP-activated protein kinase.,Sci Rep.2017,7:778
Zhenjian Li,Yannan Tang,Yiran Wu,Suwen Zhao,Juan Bao,Yitian Luo,Dianfan Li.,Structural insights into the committed step of bacterial phospholipid biosynthesis.,Nat Commun2018,8:169.
Yao Chen,Yuxuan Zheng,Yun Gao,Zhen Lin,Suming Yang,Tongtong Wang,Qiu Wang,Nannan Xie,Rong Hua,Mingxi Liu,Jiahao Sha,Michael D.Griswold,Jinsong Li,Fuchou Tang,Minghan Tong,Single-cell RNA-seq uncovers dynamic processes and critical regulators in mouse spermatogenesis,Cell Res2018 Jul 30
Wei Wu,Qiuping Zhou,Takeya Masubuchi,Xiaoshan Shi,Hua Li,Xinyi Xu,Min Huang,Li Meng,Xing He,Hengyu Zhu,Shuaixin Gao,Nan Zhang,Ruirui Jing,Jie Sun, Haopeng Wang,Enfu Hui,Catherine Chiulan Wong,Chenqi Xu,Multiple Signaling Roles of CD3ε and Its Application in CAR-T Cell Therapy,Cell2020 Jul 29.
Xing Deng,Xin Zhang,Weiping Li,Renxin Feng,Lu Li,Guirong Yi,Xiaonan Zhang,Chuan Yin,Hongyu Yu,Junping Zhang,Bin Lu,Lijian Hui,Weifen Xie,Chronic Liver Injury Induces Conversion of Biliary Epithelial Cells into Hepatocytes,Cell Stem Cell2018 Jun 7

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