Representative Publications----Institute of Biochemistry and Cell Biology, Shanghai Institute for Biological Sciences, CAS

Research

Du H, Zhao Y, He J, Zhang Y, Xi H, Liu M, Ma J* and Wu L*,YTHDF2 destabilizes m6A-containing RNA through direct recruitment of the CCR4-NOT deadenylase complex,nature communications10.1038
Xiangbo Meng,Xiwei Liu,Xingdong Guo,Shutan Jiang,Tingting Chen,Zhiqiang Hu,Haifeng Liu,Yibing Bai,Manman Xue,Ronggui Hu,Shao-cong Sun,Xiaolong Liu,Penghui Zhou,Xiaowu Huang,Lai Wei,Wei Yang,Chenqi Xu,FBXO38 mediates PD-1 ubiquitination and regulates anti-tumour immunity of T cells,Nature2018 Nov 28
Qiyuan Yang,Ronghong Li,Qifeng Lyu,Li Hou,Zhen Liu,Qiang Sun,Miao Liu,Huijuan Shi,Beiying Xu,Mingru Yin,Zhiguang Yan,Ying Huang,Mofang Liu,Yiping Li,Ligang Wu,Single-cell CAS-seq reveals a class of short PIWI-interacting RNAs in human oocytes,Nat Commun2019 Jul 29
Xueying Tian,Lingjuan He,Kuo Liu,Wenjuan Pu,Huan Zhao,Yan Li,Xiuxiu Liu,Muxue Tang,Ruilin Sun,Jian Fei,Yong Ji,Zengyong Qiao,Kathy O Lui,Bin Zhou,Generation of a self‐cleaved inducible Cre recombinase for efficient temporal genetic manipulation,EMBO J2020 Jan 14.
Feng Li, Ping Yi, Jingnan Pi, Lanfang Li, Jingyi Hui, Fang Wang, Aihua Liang, Jia Yu,QKI5-mediated alternative splicing of the histone variant macroH2A1 regulates gastric carcinogenesis,Oncotarget7（22）：32821-32824
Ludi Zhang,Lijian Hui,Bioengineering: Bile ducts regenerated.,Nature2017,547:171-172.
Zhuangfeng Weng, Chenghao Situ, Lin Lin, Zhenguo Wu, Jinwei Zhu，Rongguang Zhang,Structure of BAI1/ELMO2 complex reveals an action mechanism of adhesion GPCRs via ELMO family scaffolds,Nat Commun2019 Jan 3
Chuanyin Li, Wenli Lu, Liguang Yang, Zhengwei Li, Xiaoyi Zhou, Rong Guo, Junqi Wang, Zhebao Wu, Zhiya Dong, Guang Ning, Yujiang Shi, Yinmin Gu, Peng Chen, Zijian Hao, Tianting Han, Meiqiang Yang, Wei Wang, Xuehui Huang, Yixue Li, Shan Gao, Ronggui Hu,MKRN3 regulates the epigenetic switch of mammalian puberty via ubiquitination of MBD3,Natl Sci Rev2020 Feb 14.
Zhixin Qiu, Keke Zou, Liping Zhuang, Jianjie Qin, Hong Li, Chao Li, Zhengtao Zhang, Xiaotao Chen, Jin Cen, Zhiqiang Meng, Haibin Zhang, Yixue Li , Lijian Hui,Hepatocellular carcinoma cell lines retain the genomic and transcriptomic landscapes of primary human cancers.,Scientific Reports7;6:27411
Juan Xu,Guangxin Yao,Yanfei Ru,Shengsong Xie,Expression of tamoxifen-inducible CRE recombinase in Lcn5-CreERT2 transgenic mouse caput epididymis,Mol Reprod Dev2017,84:257-264
Zhenjian Li,Yannan Tang,Yiran Wu,Suwen Zhao,Juan Bao,Yitian Luo,Dianfan Li.,Structural insights into the committed step of bacterial phospholipid biosynthesis.,Nat Commun2017,8:1691
Wei Yang, Weiling Pan, Shuokai Chen, Nicola Trendel, Shutan Jiang, Feng Xiao, Manman Xue, Wei Wu, Zeli Peng, Xiaoxi Li, Hongbin Ji, Xiaolong Liu, Hai Jiang, Haopeng Wang, Hongbin Shen, Omer Dushek, Hua Li, Chenqi Xu.,Dynamic regulation of CD28 conformation and signaling by charged lipids and ions,Nature Structural & Molecular Biology2017,24:1081
Wenjuan Pu,Lingjuan He,Ximeng Han,Xueying Tian,Yan Li,Hui Zhang,Qiaozhen Liu,Xiuzhen Huang,Libo Zhang, Qingdong Wang,Zhenyang Yu,Xiao Yang,Nicola Smart,Bin Zhou,Genetic Targeting of Organ-Specific Blood Vessels,Circ Res2018 May 15
Xufeng Chen, Jingyao Zhao, Chan Gu, Yu Cui, Yuling Dai, Guangrong Song, Haifeng Liu, Hao Shen, Yuanhua Liu, Yuya Wang, Huayue Xing, Xiaoyan Zhu, Pei Hao, Fan Guo, Xiaolong Liu,Med23 serves as a gatekeeper of the myeloid potential of hematopoietic stem cells,Nat Commun2018 Sep 14
Xiangdong Lv, Chenyu Pan, Zhao Zhang, Yuanxin Xia, Hao Chen, Shuo Zhang,Tong Guo, Hui Han, Haiyun Song, Lei Zhang, and Yun Zhao,SUMO Regulates Somatic Cyst Stem Cells Maintenance and Directly TargetsHedgehog Pathway in Adult Drosophila Testis.,Development43(10):1655-62
Mingliang Jin,Wenyu Han,Caixuan Liu,Yunxiang Zang,Jiawei Li,Fangfang Wang,Yanxing Wang,Yao Cong,An ensemble of cryo-EM structures of TRiC reveal its conformational landscape and subunit specificity,Proc Natl Acad Sci USA2019 Sep 6
Jinlong Suo,Xue Feng,Jiayi Li,Jinghui Wang,Zuoyun Wang,Lei Zhang,Weiguo Zou,Zuoyun Wang,Lei Zhang,Weiguo Zou,VGLL4 promotes osteoblast differentiation by antagonizing TEADs-inhibited Runx2 transcription,Sci Adv2020 Oct 28.
Aijie Xin, Li Cheng, Hua Diao, Yancheng Wu, Shumin Zhou, Changgen Shi, Yangyang Sun, Peng Wang, Shiwei Duan, Jufen Zheng, Bin Wu, Yao Yuan, Yihua Gu, Guowu Chen, Xiaoxi Sun, Huijuan Shi, Shengce Tao, Yonglian Zhang.,Lectin binding of human sperm associates with DEFB126 mutation and serves as a potential biomarker for subfertility.,Sci Rep
XiaoLei？Shi, Yimeng？Gao, Yupeng？Yan, Hucheng？Ma, Lulu？Sun, Pengyu？Huang, Xuan？Ni, Ludi？Zhang, Xin？Zhao, Haozhen？Ren, Dan？Hu, Yan？Zhou, Feng？Tian, Yuan？Ji, Xin？Cheng, Guoyu？Pan, YiTao？Ding？,Lijian？Hui,Improved survival of porcine acute liver failure by a bioartificial liver device implanted with induced human functional hepatocytes.,Cell Research26(2):206-16
Liyong Zeng, Cheguo Cai, Shan Li, Wenjuan Wang, Yaping Li, Jiangye Chen,Xueliang Zhu*, Yi Arial Zeng*,Essential Roles of Cyclin Y-Like 1 and Cyclin Y in Dividing Wnt-Responsive Mammary Stem/Progenitor Cells,PLoS Genetics12(5): e1006055

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