Representative Publications----Institute of Biochemistry and Cell Biology, Shanghai Institute for Biological Sciences, CAS

Research

Qiang Gao,Hongwen Zhu,Liangqing Dong,Weiwei Shi,Ran Chen,Zhijian Song,Chen Huang,Junqiang Li,Xiaowei Dong,Yanting Zhou,Qian Liu,Lijie Ma,Xiaoying Wang,Jian Zhou,Yansheng Liu,Emily Boja,Ana I.Robles,Weiping Ma,Pei Wang,Yize Li,Li Ding,Bo Wen,Bing Zhang,Henry Rodriguez,Daming Gao,Hu Zhou,Jia Fan,Integrated Proteogenomic Characterization of HBV-Related Hepatocellular Carcinoma,Cell2019 Oct 3
Yang Tang, Gemin Fang, Fenghua Guo, Hui Zhang, Xiaoxu Chen, Liwei An, Min Chen, Li Zhou, Wenjia Wang, Tiantian Ye, Lei Zhou, Pingping Nie, Haijun Yu, Moubin Lin, Yun Zhao, Xinhua Lin, Zengqiang Yuan, Shi Jiao, Zhaocai Zhou,Selective Inhibition of STRN3-Containing PP2A Phosphatase Restores Hippo Tumor-Suppressor Activity in Gastric Cancer,Cancer Cell2020 Jun 25.
Xueying Tian,Lingjuan He,Kuo Liu,Wenjuan Pu,Huan Zhao,Yan Li,Xiuxiu Liu,Muxue Tang,Ruilin Sun,Jian Fei,Yong Ji,Zengyong Qiao,Kathy O Lui,Bin Zhou,Generation of a self-cleaved inducible Cre recombinase for efficient temporal genetic manipulation,EMBO J2020 Feb 17.
Linlin Zhao, Shuqing Wang, Changqing Run, Bo OuYang, James J. Chou,Specific Lipid Binding of Membrane Proteins in Detergent Micelles Characterized by NMR and Molecular Dynamics,Biochemistry55(38), 5317-5320
Chen Fan, Xiaohua Ye, Zhiqiang Ku, Liangliang Kong, Qingwei Liu, Cong Xu, Yao Cong, Zhong Huang,Beta-propiolactone inactivation of coxsackievirus A16 induces structural alteration and surface modification of viral capsids.,J Virol2017,91.e00038-17
Xiaoli He, Wenjuan Zhang, Chen Yan, Fen Nie, Chen Li, Xiaofen Liu, Cong Fei, Shengdi Li, Xiaomin Song, Yingying Jia, Rong Zeng, Dianqing Wu, Weijun Pan, Xiaojiang Hao, Lin Li,Chemical biology reveals CARF as a positive regulator of canonical Wnt signaling by promoting TCF/β-catenin transcriptional activity,Cell Discovery2017,3:17003
Hong Peng, Jiao Yang, Guangyi Li, Qing You, Wen Han, Tianrang Li, Daming Gao, Xiaoduo Xie, Byunghoon Lee, Juan Du, Jian Hou, Tao Zhang, Hai Rao, Ying Huang, Qinrun Li, Rong Zeng, Lijian Hui, Hongyan Wang, Qin Xia, Xuemin Zhang, Yongning He, Masaaki Komatsu, Ivan Dikic, Daniel Finley, Ronggui Hu.,Ubiquitylation of p62/sequestosome1 activates its autophagy receptor function and controls selective autophagy upon ubiquitin stress,Cell Res2017,27:657-674
Yingcheng Yang, Ximeng Lin, Xinyuan Lu, Guijuan Luo, Tao Zeng, Jing Tang, Feng Jiang, Liang Li, Xiuliang Cui, Wentao Huang, Guojun Hou, Xin Chen, Qing Ouyang, Shanhua Tang, Huanlin Sun, Luonan Chen, Frank J Gonzalez, Mengchao Wu, Wenming Cong, Lei Chen, Hongyang Wang.,Interferon-microRNA signalling drives liver precancerous lesion formation and hepatocarcinogenesis.,Gut
Zhen Liu, Xiao Yao, Guang Yan, Yichi Xu, Jun Yan, Weiguo Zou*, Gang Wang*.,Mediator MED23 cooperates with RUNX2 to drive osteoblast differentiation and bone development.,Nat CommunApr 1;7:
Jun Guo,Chenqi Xu,Screening for the Next-Generation T Cell Therapies,Cancer Cell2020 May 11.
Chang Liu,Xiaoyan Xu,Lei Han,Xiaopeng Wan,Lingming Zheng,Chunyang Li,Zhaohui Liao,Jun Xiao,Ruiyue Zhong,Xin Zheng,Qiong Wang,Zonghai Li,Hualan Chen,Bin Wei,Hongyan Wang,LRCH1 deficiency enhances LAT signalosome formation and CD8 + T cell responses against tumors and pathogens,Proc Natl Acad Sci USA2020 Jul 29.
Yanni Xu, Liang Chu, Sujing Yuan, Yuanqin Yang, Yu Yang, Bin Xu, Kangjian Zhang, Xinyuan Liu, Ruwei Wang, Ling Fang, Zhinan Chen,Zongsuo Liang.,RGD-modified oncolytic adenovirus-harboring shPKM2 exhibits a potent cytotoxic effect in pancreatic cancer via autophagy inhibition and apoptosis promotion.,Cell Death Dis.2017,8:e2835
Guangdun Peng, Patrick P.L.Tam, Naihe Jing.,Lineage specification of early embryos and embryonic stem cells at the dawn of enabling technologies,Natl Sci Rev
Minghong He,Jiacheng Liu,Yisi Lu,Zhijing Wu,Yingying Liu,Zhenfang Wu,Jing Peng,Jinqiu Zhou,KEOPS complex promotes homologous recombination via DNA resection,Nucleic Acids Res2019 Apr 2
Tao Long, Jing Li, Hao Li, Mi Zhou, Xiao-Long Zhou, Ru-Juan Liu, and En-Duo Wang,Sequence-specific and shape-selective RNA recognition by the human RNA m5C methyltransferase NSun6,J. Biol. Chem.291(46), 24293-24303
Isabelle Mondor, Audrey Jorquera, Cynthia Sene, Sahil Adriouch, Ralf Heinrich Adams, Bin Zhou, Stephan Wienert, Frederick Klauschen, Marc Bajénoff,Clonal Proliferation and Stochastic Pruning Orchestrate Lymph Node Vasculature Remodeling,Immunity18 October 2016, Pages 877–888
Jia Y, Li P, Fang L, Zhu H, Xu L, Cheng H, Zhang J, Li F, Feng Y, Li Y, Li J, Wang R, Du JX, Li J, Chen T, Ji H, Han J, Yu W, Wu Q, Wong J.,Negative regulation of DNMT3A de novo DNA methylation by frequently overexpressed UHRF family proteins as a mechanism for widespread DNA hypomethylation in cancer.,Cell Discov.2016 Apr 12;2:16007.
Shichao Huang, Jianxin Mao, Kan Ding, Yue Zhou, Xianglu Zeng, Wenjuan Yang, Peipei Wang, Cun Zhao, Jian Yao, Peng Xia,Gang Pei.,Polysaccharides from Ganoderma lucidum Promote Cognitive Function and Neural Progenitor Proliferation in Mouse Model of Alzheimer's Disease.,Stem Cell Rep2017,8,84-94.
Hsinyi Huang,Wenjing Zhang,Yafang Pan,Yijun Gao,Lei Deng,Fuming Li,Fei Li,Xueyan Ma,Shenda Hou,Jing Xu,Peixue Li,Xiaoxun Li,Guohong Hu,Cheng Li,Haiquan Chen,Lei Zhang,Hongbin Ji.,YAP Suppresses Lung Squamous Cell Carcinoma Progression via Deregulation of the DNp63-GPX2 Axis and ROS Accumulation.,Cancer Res2017,77:5769-5781
Hui Zhang, Kathy O. Lui, Bin Zhou,Endocardial Cell Plasticity in Cardiac Development,Diseases and Regeneration,Circ Res2018;122:774-789

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