Representative Publications----Institute of Biochemistry and Cell Biology, Shanghai Institute for Biological Sciences, CAS

Research

Chuxiao Liu, Lingling Chen,Circular RNAs: Characterization, cellular roles, and applications,Cell2022 May 17.
Xueqing Wang, Quanlong Jiang, Yuanyuan Song, Zhidong He, Hongdao Zhang, Mengjiao Song, Xiaona Zhang, Yumin Dai, Oezlem Karalay, Christoph Dieterich, Adam Antebi, Ligang Wu, Jingdong J Han, Yidong Shen,Ageing induces tissue-specific transcriptomic changes in Caenorhabditis elegans,EMBO J2022 Mar 7.
Chuxiao Liu,Sikun Guo,Fang Nan,Yifeng Xu,Li Yang,Lingling Chen,RNA circles with minimized immunogenicity as potent PKR inhibitors,Mol Cell2021 Dec 23.
Haopeng Wang,Xianming Song,Lianjun Shen,Xinxin Wang,Chenqi Xu,Exploiting T cell signaling to optimize engineered T cell therapies,2021 Nov 19.
Tingting Li,Hongmin Cai,Hebang Yao,Bingjie Zhou,Ning Zhang,Martje Fentener van Vlissingen,Thijs Kuiken,Wenyu Han,Corine H GeurtsvanKessel,Yuhuan Gong,Yapei Zhao,Quan Shen,Wenming Qin,Xiaoxu Tian,Chao Peng,Yanling Lai,Yanxing Wang,Cedric A J Hutter,Shuming Kuo,Juan Bao,Caixuan Liu,Yifan Wang,Audrey S Richard,Hervé Raoul,Jiaming Lan,Markus A Seeger,Yao Cong,Barry Rockx,Gary Wong,Yuhai Bi,Dimitri Lavillette,Dianfan Li,A synthetic nanobody targeting RBD protects hamsters from SARS-CoV-2 infection,Nat Commun2021 Jul 30.
Shu Wang,Changdong Lin,Yue Li,Zhaoyuan Liu,Junlei Wang,Youhua Zhang,Zhanjun Yan,Yuebin Zhang,Guohui Li,Jianfeng Chen,Distinct chemokines selectively induce HIV-1 gp120-integrin α4β7 binding via triggering conformer-specific activation of α4β7,Signal Transduct Target Ther2021 Jul 16.
Tianyuan Zhao,Qing Li,Chenchen Zhou,Xiujuan Lv,Hongyan Liu,Tianxiang Tu,Na Tang,Yanbo Cheng,Xiaoyu Liu,Changbao Liu,Junzhao Zhao,Zongming Song,Haoyi Wang,Jinsong Li,Feng Gu,Small-molecule compounds boost genome-editing efficiency of cytosine base editor,Nucleic Acids Res2021 Jul 30.
Luwei He,Huaguang Li,Chenyu Pan,Yutong Hua,Jiayin Peng,Zhaocai Zhou,Yun Zhao,Moubin Lin,Squalene epoxidase promotes colorectal cancer cell proliferation through accumulating calcitriol and activating CYP24A1-mediated MAPK signaling,Cancer Commun2021 Jul 16.
Jingsong Zhang,Yang Zhang,Junyan Kang,Shuiye Chen,Yongqun He,Benhao Han,Mofang Liu,Lina Lu,Li Li,Zhigang Yi,Luonan Chen,Potential transmission chains of variant B.1.1.7 and co-mutations of SARS-CoV-2,Cell Discov2021 Jun 15.
Maorong Wen,Yunlei Cao,Bin Wu,Taoran Xiao,Ruiyu Cao,Qian Wang,Xiwei Liu,Hongjuan Xue,Yang Yu,Jialing Lin,Chenqi Xu,Jie Xu,Bo OuYang,PD-L1 degradation is regulated by electrostatic membrane association of its cytoplasmic domain,Nat Commun2021 Aug 24.
Man Wu,Guang Xu,Chong Han,Pengfei Luan,Yuhang Xing,Fang Nan,Liangzhong Yang,Youkui Huang,Zhenghu Yang,Lin Shan,Li Yang,Jiaquan Liu,Lingling Chen,lncRNA SLERT controls phase separation of FC/DFCs to facilitate Pol I transcription,Science2021 Jul 30.
Qiang Gao,Hongwen Zhu,Liangqing Dong,Weiwei Shi,Ran Chen,Zhijian Song,Chen Huang,Junqiang Li,Xiaowei Dong,Yanting Zhou,Qian Liu,Lijie Ma,Xiaoying Wang,Jian Zhou,Yansheng Liu,Emily Boja,Ana I.Robles,Weiping Ma,Pei Wang,Yize Li,Li Ding,Bo Wen,Bing Zhang,Henry Rodriguez,Daming Gao,Hu Zhou,Jia Fan,Integrated Proteogenomic Characterization of HBV-Related Hepatocellular Carcinoma,Cell2019 Oct 3
Yang Tang, Gemin Fang, Fenghua Guo, Hui Zhang, Xiaoxu Chen, Liwei An, Min Chen, Li Zhou, Wenjia Wang, Tiantian Ye, Lei Zhou, Pingping Nie, Haijun Yu, Moubin Lin, Yun Zhao, Xinhua Lin, Zengqiang Yuan, Shi Jiao, Zhaocai Zhou,Selective Inhibition of STRN3-Containing PP2A Phosphatase Restores Hippo Tumor-Suppressor Activity in Gastric Cancer,Cancer Cell2020 Jun 25.
Xueying Tian,Lingjuan He,Kuo Liu,Wenjuan Pu,Huan Zhao,Yan Li,Xiuxiu Liu,Muxue Tang,Ruilin Sun,Jian Fei,Yong Ji,Zengyong Qiao,Kathy O Lui,Bin Zhou,Generation of a self-cleaved inducible Cre recombinase for efficient temporal genetic manipulation,EMBO J2020 Feb 17.
Linlin Zhao, Shuqing Wang, Changqing Run, Bo OuYang, James J. Chou,Specific Lipid Binding of Membrane Proteins in Detergent Micelles Characterized by NMR and Molecular Dynamics,Biochemistry55(38), 5317-5320
Chen Fan, Xiaohua Ye, Zhiqiang Ku, Liangliang Kong, Qingwei Liu, Cong Xu, Yao Cong, Zhong Huang,Beta-propiolactone inactivation of coxsackievirus A16 induces structural alteration and surface modification of viral capsids.,J Virol2017,91.e00038-17
Xiaoli He, Wenjuan Zhang, Chen Yan, Fen Nie, Chen Li, Xiaofen Liu, Cong Fei, Shengdi Li, Xiaomin Song, Yingying Jia, Rong Zeng, Dianqing Wu, Weijun Pan, Xiaojiang Hao, Lin Li,Chemical biology reveals CARF as a positive regulator of canonical Wnt signaling by promoting TCF/β-catenin transcriptional activity,Cell Discovery2017,3:17003
Hong Peng, Jiao Yang, Guangyi Li, Qing You, Wen Han, Tianrang Li, Daming Gao, Xiaoduo Xie, Byunghoon Lee, Juan Du, Jian Hou, Tao Zhang, Hai Rao, Ying Huang, Qinrun Li, Rong Zeng, Lijian Hui, Hongyan Wang, Qin Xia, Xuemin Zhang, Yongning He, Masaaki Komatsu, Ivan Dikic, Daniel Finley, Ronggui Hu.,Ubiquitylation of p62/sequestosome1 activates its autophagy receptor function and controls selective autophagy upon ubiquitin stress,Cell Res2017,27:657-674
Yingcheng Yang, Ximeng Lin, Xinyuan Lu, Guijuan Luo, Tao Zeng, Jing Tang, Feng Jiang, Liang Li, Xiuliang Cui, Wentao Huang, Guojun Hou, Xin Chen, Qing Ouyang, Shanhua Tang, Huanlin Sun, Luonan Chen, Frank J Gonzalez, Mengchao Wu, Wenming Cong, Lei Chen, Hongyang Wang.,Interferon-microRNA signalling drives liver precancerous lesion formation and hepatocarcinogenesis.,Gut
Zhen Liu, Xiao Yao, Guang Yan, Yichi Xu, Jun Yan, Weiguo Zou*, Gang Wang*.,Mediator MED23 cooperates with RUNX2 to drive osteoblast differentiation and bone development.,Nat CommunApr 1;7:

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