Representative Publications----Institute of Biochemistry and Cell Biology, Shanghai Institute for Biological Sciences, CAS

Research

Lu Song, Jun Chen, Guangdun Peng, Ke Tang, NaiheJing*.,Dynamic Heterogeneity of Brachyury in Mouse Epiblast Stem Cells Mediates Distinct Respond to Extrinsic BMP Signaling.,J. Biol. Chem.291(29):15212-15225
Xu Xiao, Jingjie Tang, Chao Peng, Yan Wang, Lin Fu, Zhiping Qiu, Yue Xiong, Lianfang Yang, Haiwei Cui, Xiaolong He,Lei Yin,Wei Qi,Catherine C.L.Wong,Yun Zhao,Boliang Li, Wenwei Qiu,Baoliang Song,Cholesterol Modification of Smoothened Is Required for Hedgehog Signaling.,Mol Cell2017,66:154-162
Shimin Wang, Yi Lu, Meng-Xin Yin, Chao Wang, Wei Wu, Jinhui Li, Wenqing Wu, Ling Ge, Lianxin Hu, Yun Zhao, Lei Zhang,Importin α1 mediates Yorkie nuclear import via N-terminal non-canonical nuclear localization signal.,The Journal of Biological Chemistry2016,291(15):7926-37
Xing Liu, Chen Wang,The emerging roles of the STING adaptor protein in immunity and diseases.,ImmunologyVol 147: 285-291
Kirill Oxenoid, Ying Dong, Chan Cao, Tanxing Cui, Yasemin Sancak, Andrew L. Markhard, Zenon Grabarek, Liangliang Kong, Zhijun Liu, Bo Ouyang, Yao Cong, Vamsi K. Mootha & James J. Chou,Architecture of the Mitochondrial Calcium Uniporter,Nature533(7602), 269-273
Chen Chu,Lu Yu,Bin Wu,Li Ma,Lantao Gou,Miao He,Yunli Guo,Zhitong Li,Wei Gao,Huijuan Shi,Mofang Liu,Hongyan Wang,Charlie Degui Chen,Jo？l R.Drevet,Yuchuan Zhou,Yonglian Zhang.,A sequence of 28？S rRNA-derived small RNAs is enriched in mature sperm？andvarious somatic tissues？and？possibly associates with inflammation.,J Mol Cell Biol.2017,9:256-259
Liting Zheng,Longyong Xu.Qing Xu,Lu Yu,Danfeng Zhao,Pu Chen,Wei Wang,Yiqin Wang,Gang Han,Charlie Degui Chen,Utx loss causes myeloid transformation,Leukemia2018 Feb 20
Yan Tang, Yazhen Hong, Huajun Bai, Qiang Wu, Charlie Degu Chen,Jingyu Lang, Kenneth R.Boheler,and Huangtian Yang,PHF8 regulates mesodermal and cardiac differentiation of embryonic stem cells through mediating the histone demethylation of pmaip1,Stem Cells.2016,34:1527-40
Lianxin Hu, Jiajun Xu, Meng-Xin Yin, Liguo Zhang, Yi Lu, Wenqing Wu, Zhaoyu Xu, Margaret S. Ho, Guanjun Gao, Yun Zhao and Lei Zhang,Ack promotes tissue growth via phosphorylation and suppression of the Hippo pathway component Expanded,Cell Discovery2:15047
Du H, Zhao Y, He J, Zhang Y, Xi H, Liu M, Ma J* and Wu L*,YTHDF2 destabilizes m6A-containing RNA through direct recruitment of the CCR4-NOT deadenylase complex,nature communications10.1038
Xiangbo Meng,Xiwei Liu,Xingdong Guo,Shutan Jiang,Tingting Chen,Zhiqiang Hu,Haifeng Liu,Yibing Bai,Manman Xue,Ronggui Hu,Shao-cong Sun,Xiaolong Liu,Penghui Zhou,Xiaowu Huang,Lai Wei,Wei Yang,Chenqi Xu,FBXO38 mediates PD-1 ubiquitination and regulates anti-tumour immunity of T cells,Nature2018 Nov 28
Qiyuan Yang,Ronghong Li,Qifeng Lyu,Li Hou,Zhen Liu,Qiang Sun,Miao Liu,Huijuan Shi,Beiying Xu,Mingru Yin,Zhiguang Yan,Ying Huang,Mofang Liu,Yiping Li,Ligang Wu,Single-cell CAS-seq reveals a class of short PIWI-interacting RNAs in human oocytes,Nat Commun2019 Jul 29
Xueying Tian,Lingjuan He,Kuo Liu,Wenjuan Pu,Huan Zhao,Yan Li,Xiuxiu Liu,Muxue Tang,Ruilin Sun,Jian Fei,Yong Ji,Zengyong Qiao,Kathy O Lui,Bin Zhou,Generation of a self‐cleaved inducible Cre recombinase for efficient temporal genetic manipulation,EMBO J2020 Jan 14.
Feng Li, Ping Yi, Jingnan Pi, Lanfang Li, Jingyi Hui, Fang Wang, Aihua Liang, Jia Yu,QKI5-mediated alternative splicing of the histone variant macroH2A1 regulates gastric carcinogenesis,Oncotarget7（22）：32821-32824
Ludi Zhang,Lijian Hui,Bioengineering: Bile ducts regenerated.,Nature2017,547:171-172.
Zhuangfeng Weng, Chenghao Situ, Lin Lin, Zhenguo Wu, Jinwei Zhu，Rongguang Zhang,Structure of BAI1/ELMO2 complex reveals an action mechanism of adhesion GPCRs via ELMO family scaffolds,Nat Commun2019 Jan 3
Chuanyin Li, Wenli Lu, Liguang Yang, Zhengwei Li, Xiaoyi Zhou, Rong Guo, Junqi Wang, Zhebao Wu, Zhiya Dong, Guang Ning, Yujiang Shi, Yinmin Gu, Peng Chen, Zijian Hao, Tianting Han, Meiqiang Yang, Wei Wang, Xuehui Huang, Yixue Li, Shan Gao, Ronggui Hu,MKRN3 regulates the epigenetic switch of mammalian puberty via ubiquitination of MBD3,Natl Sci Rev2020 Feb 14.
Zhixin Qiu, Keke Zou, Liping Zhuang, Jianjie Qin, Hong Li, Chao Li, Zhengtao Zhang, Xiaotao Chen, Jin Cen, Zhiqiang Meng, Haibin Zhang, Yixue Li , Lijian Hui,Hepatocellular carcinoma cell lines retain the genomic and transcriptomic landscapes of primary human cancers.,Scientific Reports7;6:27411
Juan Xu,Guangxin Yao,Yanfei Ru,Shengsong Xie,Expression of tamoxifen-inducible CRE recombinase in Lcn5-CreERT2 transgenic mouse caput epididymis,Mol Reprod Dev2017,84:257-264
Zhenjian Li,Yannan Tang,Yiran Wu,Suwen Zhao,Juan Bao,Yitian Luo,Dianfan Li.,Structural insights into the committed step of bacterial phospholipid biosynthesis.,Nat Commun2017,8:1691

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