Representative Publications----Institute of Biochemistry and Cell Biology, Shanghai Institute for Biological Sciences, CAS

Research

Daisong Wang,Xin Hu,Chunye Liu,Yingying Jia,Yiqin Bai,Cheguo Cai,Jingqiang Wang,Lanyue Bai,Ruikai Yang,ChangDong Lin,Yirong Liu,Shan Li,Feng Qiao,Ling Yao,Li Chen,Gaoxiang Ge,Hai Jiang,Dianfan Li,Lin Li,JianFeng Chen,Zhiming Shao,Yi Arial Zeng,Protein C receptor is a therapeutic stem cell target in a distinct group of breast cancers,Cell Res2019 Sep 3
Jun Xiao,Weiyun Li,Xin Zheng,Linlin Qi,Hui Wang,Chi Zhang,Xiaopeng Wan,Yuxiao Zheng,Ruiyue Zhong,Xin Zhou,Yao Lu,Zhiqi Li,Ying Qiu,Chang Liu,Fang Zhang,Yanbo Zhang,Xiaoyan Xu,Zhongzhou Yang,Hualan Chen,Qiwei Zhai,Bin Wei,Hongyan Wang,Targeting 7-Dehydrocholesterol Reductase Integrates Cholesterol Metabolism and IRF3 Activation to Eliminate Infection,Immunity2019 Dec 24
Lei-Lei Jiang, Jian Zhao, Xiao-Fang Yin, Wen-Tian He, Hui Yang, Mei-Xia Che and Hong-Yu Hu*,Two mutations G335D and Q343R within the amyloidogenic core region of TDP-43 influence its aggregation and inclusion formation.,Scientific Reports6: 23928
Kirill Oxenoid, Ying Dong, Chan Cao, Tanxing Cui, Yasemin Sancak, Andrew L. Markhard, Zenon Grabarek, Liangliang Kong, Zhijun Liu, Bo Ouyang, Yao Cong, Vamsi K. Mootha & James J. Chou,Architecture of the mitochondrial calcium uniporter,Nature533, 269–273
Chuanchao Zhang, Jiguang Wang, Juan Liu, Dong Xu, Luonan Chen,Network stratification analysis for identifying function-specific network layers.,Molecular BioSystems
Bo Yang, Sixiu Chen, Ming Wu, Lin Zhang, Mengna Ruan, Xujiao Chen, Zhengjun Chen, Changlin Mei,Zhiguo Mao,PHF14: an innate inhibitor against the progression of renal fibrosis following folic acid-induced kidney injury.,Sci Rep2017,7:39888
Qing Ye,Quanquan Ji,Wei Yan,Fang Yang,Enduo Wang.,Acetylation of lysine ε-amino groups regulates aminoacyl-tRNA synthetase activity in Escherichia coli.,J Biol Chem2017,292:10709-10722
Zhengang Tao,Xia Meng,Yanqi Han,Mingming Xue,Shifei Wu,Ping Wu,Ying Yuan,Zhu Qiang,Tiejun Zhang,Catherine CL Wong.,Therapeutic Mechanism Studies of ShuFengJieDu Capsule on an Acute Lung Injury Animal Model Using Quantitative Proteomics Technology,J Proteome Res.
Andreas Bietz,Hengyu Zhu,Manman Xue,Chenqi Xu,Cholesterol Metabolism in T Cells,Front Immunol
Nan Qi,Yuheng Shi,Rui Zhang,Wenting Zhu,Bofeng Yuan,Xiaoyan Li,Changwan Wang,Xuewu Zhang,Fajian Hou,Multiple truncated isoforms of MAVS prevent its spontaneous aggregation in antiviral innate immune signalling,Nat Commun2017,8:15676
Yun Chen, Zhirong Ruan, Yong Wang, Qian Huang, Meiqin Xue, Xiaolong Zhou,Enduo Wang,A threonyl-tRNA synthetase-like protein has tRNA aminoacylation and editing activities,Nucleic Acids Res2018 Mar 20
Xiaoping Liu,Xiao Chang,Siyang Leng,Hui Tang,Kazuyuki Aihara,Luonan Chen,Detection for disease tipping points by landscape dynamic network biomarkers,Natl Sci Rev2018 Dec 28
Yan Li,Zan Lv,Lingjuan He,Xiuzhen Huang,Shaohua Zhang,Huan Zhao,Wenjuan Pu,Yi Li,Wei Yu,Libo Zhang,Xiuxiu Liu,Kuo Liu,Juan Tang,Xueying Tian,Qingdong Wang,Kathy O.Lui,Bin Zhou,Genetic Tracing Identifies Early Segregation of the Cardiomyocyte and Non-Myocyte Lineages,Circ Res2019 Jun 12
Lingbo Wang,Ying Zhang,Xiaoyi Fu,Shuangshuang Dong,Shuyan Tang,Ning Zhang,Chengcheng Song,Nan Yang,Lin Zhang,Hongyan Wang,Huijuan Shi,Li Jin,Feng Zhang,Jinsong Li,Keqin Hua,Joint utilization of genetic analysis and semi-cloning technology reveals a digenic etiology of Müllerian anomalies,Cell Res2019 Oct 18
YingYu Zhang,ZhenYan Fu,Jian Wei,Wei Qi,Gulinaer Baituola,Jie Luo,YaJie Meng,Shuyuan Guo,Huiyong Yin, Shiyou Jiang,Yunfeng Li,Honghua Miao,Yong Liu,Yan Wang,Boliang Li,Yitong Ma,Baoliang Song,A LIMA1 variant promotes low plasma LDL cholesterol and decreases intestinal cholesterol absorption,Science2018,360:1087-1092
Fengjuan Zhang,Ying Zhang,Xiaolong Lv,Beiying Xu,Hongdao Zhang,Jun Yan,Haipeng Li,Ligang Wu,Evolution of an X-linked miRNA family predominantly expressed in mammalian male germ cells,Mol Biol Evol2019 Jan 14
Xin Wang,Zhitong Li,Yue Yan,Penghui Lin,Wei Tang,Daniele Hasler,Rajyalakshmi Meduri,Ye Li,Minmin Hua,Huitao Qi,Dihang Lin,Huijuan Shi,Jingyi Hui,Jinsong Li,Dangsheng Li,Jianhua Yang,Jinzhong Lin,Gunter Meister,Utz Fischer,Mofang Liu,LARP7-Mediated U6 snRNA Modification Ensures Splicing Fidelity and Spermatogenesis in Mice,Mol Cell2020 Feb 3.
Hui Hong,Shun Yao,Yuanyuan Zhang,Yi Ye,Cheng Li,Liang Hu,Yihua Sun,Hsinyi Huang,Hongbin Ji,In vivo miRNA knockout screening identifies miR-190b as a novel tumor suppressor,PLoS Genet2020 Nov 2.
Chunyi Hu,Haruna Inoue,Wenqi Sun,Yumiko Takeshita,Yaoguang Huang,Ying Xu,Junko Kanoh,Yong Chen？,Structural insights into chromosome attachment to the nuclear envelope by an inner nuclear membrane protein Bqt4 in fission yeast,Nucleic Acids Res2018 Nov 20
Yujiao Han,Heng Feng,Jun Sun,Xiaoting Liang,Zhuo Wang,Wenhui Xing,Qinggang Dai,Yang Yang,Anjia Han,Zhanying Wei,Qing Bi,Hongbin Ji,Tiebang Kang,Weiguo Zou,Lkb1 deletion in periosteal mesenchymal progenitors induces osteogenic tumors through mTORC1 activation,J Clin Invest2019 Feb 26

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