Representative Publications----Institute of Biochemistry and Cell Biology, Shanghai Institute for Biological Sciences, CAS

Research

Yun Chen, Zhirong Ruan, Yong Wang, Qian Huang, Meiqin Xue, Xiaolong Zhou,Enduo Wang,A threonyl-tRNA synthetase-like protein has tRNA aminoacylation and editing activities,Nucleic Acids Res2018 Mar 20
Xiaoping Liu,Xiao Chang,Siyang Leng,Hui Tang,Kazuyuki Aihara,Luonan Chen,Detection for disease tipping points by landscape dynamic network biomarkers,Natl Sci Rev2018 Dec 28
Yan Li,Zan Lv,Lingjuan He,Xiuzhen Huang,Shaohua Zhang,Huan Zhao,Wenjuan Pu,Yi Li,Wei Yu,Libo Zhang,Xiuxiu Liu,Kuo Liu,Juan Tang,Xueying Tian,Qingdong Wang,Kathy O.Lui,Bin Zhou,Genetic Tracing Identifies Early Segregation of the Cardiomyocyte and Non-Myocyte Lineages,Circ Res2019 Jun 12
Lingbo Wang,Ying Zhang,Xiaoyi Fu,Shuangshuang Dong,Shuyan Tang,Ning Zhang,Chengcheng Song,Nan Yang,Lin Zhang,Hongyan Wang,Huijuan Shi,Li Jin,Feng Zhang,Jinsong Li,Keqin Hua,Joint utilization of genetic analysis and semi-cloning technology reveals a digenic etiology of Müllerian anomalies,Cell Res2019 Oct 18
YingYu Zhang,ZhenYan Fu,Jian Wei,Wei Qi,Gulinaer Baituola,Jie Luo,YaJie Meng,Shuyuan Guo,Huiyong Yin, Shiyou Jiang,Yunfeng Li,Honghua Miao,Yong Liu,Yan Wang,Boliang Li,Yitong Ma,Baoliang Song,A LIMA1 variant promotes low plasma LDL cholesterol and decreases intestinal cholesterol absorption,Science2018,360:1087-1092
Fengjuan Zhang,Ying Zhang,Xiaolong Lv,Beiying Xu,Hongdao Zhang,Jun Yan,Haipeng Li,Ligang Wu,Evolution of an X-linked miRNA family predominantly expressed in mammalian male germ cells,Mol Biol Evol2019 Jan 14
Xin Wang,Zhitong Li,Yue Yan,Penghui Lin,Wei Tang,Daniele Hasler,Rajyalakshmi Meduri,Ye Li,Minmin Hua,Huitao Qi,Dihang Lin,Huijuan Shi,Jingyi Hui,Jinsong Li,Dangsheng Li,Jianhua Yang,Jinzhong Lin,Gunter Meister,Utz Fischer,Mofang Liu,LARP7-Mediated U6 snRNA Modification Ensures Splicing Fidelity and Spermatogenesis in Mice,Mol Cell2020 Feb 3.
Hui Hong,Shun Yao,Yuanyuan Zhang,Yi Ye,Cheng Li,Liang Hu,Yihua Sun,Hsinyi Huang,Hongbin Ji,In vivo miRNA knockout screening identifies miR-190b as a novel tumor suppressor,PLoS Genet2020 Nov 2.
Chunyi Hu,Haruna Inoue,Wenqi Sun,Yumiko Takeshita,Yaoguang Huang,Ying Xu,Junko Kanoh,Yong Chen？,Structural insights into chromosome attachment to the nuclear envelope by an inner nuclear membrane protein Bqt4 in fission yeast,Nucleic Acids Res2018 Nov 20
Yujiao Han,Heng Feng,Jun Sun,Xiaoting Liang,Zhuo Wang,Wenhui Xing,Qinggang Dai,Yang Yang,Anjia Han,Zhanying Wei,Qing Bi,Hongbin Ji,Tiebang Kang,Weiguo Zou,Lkb1 deletion in periosteal mesenchymal progenitors induces osteogenic tumors through mTORC1 activation,J Clin Invest2019 Feb 26
Xiaoduo Xie, Hongli Hu, Xinyuan Tong, Long Li, Xiangyuan Liu, Min Chen, Huairui Yuan, Xia Xie, Qingrun Li,Yuxue Zhang,Huafang Ouyang,Mengqi Wei,Jing Huang,Pengda Liu,Wenjian Gan,Yong Liu,Anyong Xie,Xiaoling Kuai,Gungwei Chirn,Hu Zhou,Rong Zeng,Ronggui Hu,Jun Qin,Feilong Meng,Wenyi Wei,Hongbin Ji,Daming Gao,The mTOR-S6K pathway links growth signaling to DNA damage response by targeting RNF168,Nat Cell Biol2018,Feb 5
Qiyu Zeng,Guixin Peng,Guang Li,Jingbo Zhou,Wenqiang Zheng,Meiqin Xue,Enduo Wang,Xiaolong Zhou,The G3-U70-independent tRNA recognition by human mitochondrial alanyl-tRNA synthetase,Nucleic Acids Res2019 Feb 15
Runwen Yao,Guang Xu,Ying Wang,Lin Shan,Pengfei Luan,Yang Wang,Man Wu,Liangzhong Yang,Yuhang Xing,Li Yang,Lingling Chen,Nascent Pre-rRNA Sorting via Phase SeparationDrives the Assembly of Dense Fibrillar Componentsin the Human Nucleolus,Mol Cell2019 Sep 17
Chao Zhang,Yifan Wang,Yuanfei Zhu,Caixuan Liu,Chenjian Gu,Shiqi Xu,Yalei Wang,Yu Zhou,Yanxing Wang,Wenyu Han,Xiaoyu Hong,Yong Yang,Xueyang Zhang,Tingfeng Wang,Cong Xu,Qin Hong,Shutian Wang,Qiaoyu Zhao,Weihua Qiao,Jinkai Zang,Liangliang Kong,Fangfang Wang,Haikun Wang,Di Qu,Dimitri Lavillette,Hong Tang,Qiang Deng,Youhua Xie,Yao Cong,Zhong Huang,Development and structural basis of a two-Mab cocktail for treating SARS-CoV-2 infections,Nat Commun2021 Jan 11.
Guochao Chen,Duo Wang,Bin Wu,Fuxiang Yan,Hongjuan Xue,Quanmeng Wang,Shu Quan,Yong Chen,Taf14 recognizes a common motif in transcriptional machineries and facilitates their clustering by phase separation,Nat Commun2020 Aug 21.
Zhang K, Zhao H, Ji Z, Zhang C, Zhou P, Wang L, Chen Q, Wang J, Zhang P, Chen Z, Zhu HH, Gao WQ.,Shp2 promotes metastasis of prostate cancer by attenuating the PAR3/PAR6/aPKC polarity protein complex and enhancing epithelial-to-mesenchymal transition.,Oncogene10;35(10):1271-82.
Xiao-Ou Zhang, Rui Dong, Yang Zhang, Jia-Lin Zhang, Zheng Luo, Jun Zhang, Ling-Ling Chen and Li Yang,Diverse alternative back-splicing and alternative splicing landscape of circular RNAs,Genome Res26:1277-1287
Zhen Wang, Jifeng Zhang, Hong Li, Junyi Li, Manabu Niimi, Guohui Ding,,Hyperlipidemia-associated gene variations and expression patterns revealed by whole-genome and transcriptome sequencing of rabbit models,Scientific Reports
Cheng J, Zhang T, Ji H, Tao K, Guo J, Wei W.,Functional characterization of AMP-activated protein kinase signaling in tumorigenesis.,Biochim Biophys Acta.2016 Sep 25;1866(2):232-251.
Qianqian Shi, Chuanchao Zhang, Weifeng Guo, Tao Zeng, Lina Lu, Zhonglin Jiang, Ziming Wang,Juan Liu,Luonan Chen,Local network component analysis for quantifying transcription factor activities.,Methods2017,124:25-35

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