Representative Publications----Institute of Biochemistry and Cell Biology, Shanghai Institute for Biological Sciences, CAS

Research

Ke？Wang,Min？Shi,Hong？Cheng,Microinjection and Fluorescence In Situ Hybridization Assay for Studying mRNA Export in Mammalian Cells.,Methods Mol Biol.2017,1648:95-102
Yi Jacky Peng,Hua Yu,Xiaoxin Hao,Wenjie Dong,Xiujuan Yin,Minghui Lin,Junke Zheng,Bo O Zhou,Luteinizing hormone signaling restricts hematopoietic stem cell expansion during puberty,EMBO J2018 Jul 23
Meiyi Li, Chen Li, Weixin Liu, Conghui Liu, Jingru Cui, Qingrun Li, Hong Ni, Yingcheng Yang, Chaochao Wu, Chunlei Chen, Xing Zhen, Tao Zeng, Mujun Zhao, Lei Chen, Jiarui Wu, Rong Zeng, Luonan Chen.,Dysfunction of PLA2G6 and CYP2C44-associated network signals imminent carcinogenesis from chronic inflammation to hepatocellular carcinoma.,J Mol？Cell？Biol.2017,001-015
Yuejia Huang, Teng Li，Stephanie C.Ems-McClung,Claire E.Walczak, Claude Prigent, Xueliang Zhu, Xuemin Zhang,Yixian Zheng.,Aurora A activation in mitosis promoted by BuGZ,J？Cell？Biol
Qian Xiao,Jibo Wu,Weijia Wang,Shiyang Chen,Yingxia Zheng,Xiaoqing Yu,Katrina Meeth,Mahnaz Sahraei,Alfred L M Bothwel,Lieping Chen,Marcus Bosenberg,Jianfeng Chen,Veronika Sexl,Le Sun,Lin Li,Wenwen Tang,Dianqing Wu,DKK2 imparts tumor immunity evasion through β-catenin-independent suppression of cytotoxic immune-cell activation,Nat Med2018,Feb 12
Qing Li, Yanjing Li, Suming Yang, Shuo Huang, Meng Yan, Yifu Ding, Wei Tang, Xiwen Lou,Qi Yin, Zhanfei Sun, Lei Lu, Huijuan Shi, Hongyan Wang, Yong Chen，Jinsong Li,CRISPR–Cas9-mediated base-editing screening in mice identifies DND1 amino acids that are critical for primordial germ cell development,Nature Cell Biology2018 Oct 1
Jianshu Wang,Jiyun Chen,Guifen Wu,Hongling Zhang,Xian Du,Suli Chen,Li Zhang,Ke Wang,Jing Fan,Shuaixin Gao,Xudong Wu,Shouxiang Zhang,Bin Kuai,Peng Zhao,Binkai Chi,Lantian Wang,Guohui Li,Catherine C.L.Wong, Yu Zhou,Jinsong Li,Caihong Yun,Hong Cheng,NRDE2 negatively regulates exosome functions by inhibiting MTR4 recruitment and exosome interaction,Genes Dev2019 Mar 6
Weiping Li,Liguang Yang,Qiang He,Chaobo Hu,Linying Zhu,Xiaolong Ma,Xueyan Ma,Shujie Bao,Lu Li,Yingying Chen,Xing Deng,Xin Zhang,Jin Cen,Lei Zhang,Zhong Wang,Weifen Xie,Hong Li,Yixue Li,Lijian Hui,A Homeostatic Arid1a-Dependent Permissive Chromatin State Licenses Hepatocyte Responsiveness to Liver-Injury-Associated YAP Signaling,Cell Stem Cell2019 July 3
Zhixin Qiu,Hong Li,Zhengtao Zhang,Zhenfeng Zhu,Sheng He,Xujun Wang,Pengcheng Wang,Jianjie Qin,Liping Zhuang,Wei Wang,Fubo Xie,Ying Gu,Keke Zou,Chao Li,Chun Li,Chenhua Wang,Jin Cen,Xiaotao Chen,Yajing Shu,Zhao Zhang,Lulu Sun,Lihua Min,Yong Fu,Xiaowu Huang,Hui Lv,He Zhou,Yuan Ji,Zhigang Zhang,Zhiqiang Meng,Xiaolei Shi,Haibin Zhang,Yixue Li,Lijian Hui,A Pharmacogenomic Landscape in Human Liver Cancers,Cancer Cell2019 Aug 1
Guangdun Peng,Shengbao Suo,Guizhong Cui,Fang Yu,Ran Wang,Jun Chen,Shirui Chen,Zhiwen Liu,Guoyu Chen,Yun Qian,Patrick P.L.Tam,Jingdong J.Han,Naihe Jing,Molecular architecture of lineage allocation and tissue organization in early mouse embryo,Nature2019 Aug 7
Daisong Wang,Xin Hu,Chunye Liu,Yingying Jia,Yiqin Bai,Cheguo Cai,Jingqiang Wang,Lanyue Bai,Ruikai Yang,ChangDong Lin,Yirong Liu,Shan Li,Feng Qiao,Ling Yao,Li Chen,Gaoxiang Ge,Hai Jiang,Dianfan Li,Lin Li,JianFeng Chen,Zhiming Shao,Yi Arial Zeng,Protein C receptor is a therapeutic stem cell target in a distinct group of breast cancers,Cell Res2019 Sep 3
Jun Xiao,Weiyun Li,Xin Zheng,Linlin Qi,Hui Wang,Chi Zhang,Xiaopeng Wan,Yuxiao Zheng,Ruiyue Zhong,Xin Zhou,Yao Lu,Zhiqi Li,Ying Qiu,Chang Liu,Fang Zhang,Yanbo Zhang,Xiaoyan Xu,Zhongzhou Yang,Hualan Chen,Qiwei Zhai,Bin Wei,Hongyan Wang,Targeting 7-Dehydrocholesterol Reductase Integrates Cholesterol Metabolism and IRF3 Activation to Eliminate Infection,Immunity2019 Dec 24
Lei-Lei Jiang, Jian Zhao, Xiao-Fang Yin, Wen-Tian He, Hui Yang, Mei-Xia Che and Hong-Yu Hu*,Two mutations G335D and Q343R within the amyloidogenic core region of TDP-43 influence its aggregation and inclusion formation.,Scientific Reports6: 23928
Kirill Oxenoid, Ying Dong, Chan Cao, Tanxing Cui, Yasemin Sancak, Andrew L. Markhard, Zenon Grabarek, Liangliang Kong, Zhijun Liu, Bo Ouyang, Yao Cong, Vamsi K. Mootha & James J. Chou,Architecture of the mitochondrial calcium uniporter,Nature533, 269–273
Chuanchao Zhang, Jiguang Wang, Juan Liu, Dong Xu, Luonan Chen,Network stratification analysis for identifying function-specific network layers.,Molecular BioSystems
Bo Yang, Sixiu Chen, Ming Wu, Lin Zhang, Mengna Ruan, Xujiao Chen, Zhengjun Chen, Changlin Mei,Zhiguo Mao,PHF14: an innate inhibitor against the progression of renal fibrosis following folic acid-induced kidney injury.,Sci Rep2017,7:39888
Qing Ye,Quanquan Ji,Wei Yan,Fang Yang,Enduo Wang.,Acetylation of lysine ε-amino groups regulates aminoacyl-tRNA synthetase activity in Escherichia coli.,J Biol Chem2017,292:10709-10722
Zhengang Tao,Xia Meng,Yanqi Han,Mingming Xue,Shifei Wu,Ping Wu,Ying Yuan,Zhu Qiang,Tiejun Zhang,Catherine CL Wong.,Therapeutic Mechanism Studies of ShuFengJieDu Capsule on an Acute Lung Injury Animal Model Using Quantitative Proteomics Technology,J Proteome Res.
Andreas Bietz,Hengyu Zhu,Manman Xue,Chenqi Xu,Cholesterol Metabolism in T Cells,Front Immunol
Nan Qi,Yuheng Shi,Rui Zhang,Wenting Zhu,Bofeng Yuan,Xiaoyan Li,Changwan Wang,Xuewu Zhang,Fajian Hou,Multiple truncated isoforms of MAVS prevent its spontaneous aggregation in antiviral innate immune signalling,Nat Commun2017,8:15676

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