Representative Publications----Institute of Biochemistry and Cell Biology, Shanghai Institute for Biological Sciences, CAS

Research

Ying Li, Liqin Han, Peiluan Li, Jing Ge, Yun Xue & Luonan Chen,Potential network markers and signaling pathways for B cells of COVID-19 based on single-cell condition-specific networks,BMC Genomics2023 Oct 18.
Jiaxin Li,Rui Zhang,Changwan Wang,Junyan Zhu,Miao Ren,Yingbo Jiang,Xianteng Hou,Yangting Du,Qing Wu,Shishi Qi,Lin Li,She Chen,Hui Yang,Fajian Hou,WDR77 inhibits prion-like aggregation of MAVS to limit antiviral innate immune response,Nat Commun2023 Aug 10.
Menghan Huang,Jintao Wang,Jianhui Zhang,Xueling Mao,Guixin Peng,Xiuying Lin,Daizhu Lv,Chen Yuan,Huan Lin,Enduo Wang,Xiaolong Zhou,Mitochondrial RNA m3C methyltransferase METTL8 relies on an isoform-specific N-terminal extension and modifies multiple heterogenous tRNAs,Sci Bull2023 Aug 2.
Zhengtao Zhang, Lijian Hui,Progress in patient-derived liver cancer cell models: A step forward for precision medicine,Acta Biochim Biophys Sin2023 Sep 27.
YING LI, YUEJING LU, CHEN KANG, PEILUAN LI , AND LUONAN CHEN,Revealing Tissue Heterogeneity and Spatial Dark Genes from Spatially Resolved Transcriptomics by Multiview Graph Networks,Research2023 Sep 20.
Shuo Zhang,Juan Zhao,Xiangdong Lv,Jialin Fan,Yi Lu,Tao Zeng,Hailong Wu,Luonan Chen,Yun Zhao,Analysis on gene modular network reveals morphogen-directed development robustness in Drosophila,Cell Discov2021 Jun 30.
Yanhui Xiao,Wenjing Li,Hui Yang,Lulu Pan,Liwei Zhang,Lu Lu,Jiwei Chen,Wei Wei,Jie Ye,Jiwen Li,Guohong Li,Yong Zhang,Minjia Tan,Jianping Ding,Jiemin Wong,HBO1 is a versatile histone acyltransferase critical for promoter histone acylations,Nucleic Acids Res2021 Jul 14.
Lin Shan,Jiao Yu,Zhengjin He,Shishuang Chen,Mingxian Liu,Hongyu Ding,Liang Xu,Jie Zhao,Ailing Yang,Hai Jiang,Defining relative mutational difficulty to understand cancer formation,Cell Discov2021 Jul 21.
Xueling Mao,Zihan Li,Menghan Huang,Jintao Wang,Jingbo Zhou,Qingrun Li, Hong Xu,Xijin Wang, Xiaolong Zhou,Mutually exclusive substrate selection strategy by human m3C RNA transferases METTL2A and METTL6,Nucleic Acids Res2021 Jul 15.
Yijian Zhang,Chunman Zuo,Liguo Liu,Yunping Hu,Bo Yang,Shimei Qiu,Yang Li,Dongyan Cao,Zheng Ju,Jing Ge,Qiu Wang,Ting Wang,Lu Bai,Yang Yang,Guoqiang Li,Ziyu Shao,Yuan Gao,Yongsheng Li,Rui Bian,Huijie Miao,Lin Li,Xuechuan Li,Chengkai Jiang,Siyuan Yan,Ziyi Wang,Zeyu Wang,Xuya Cui,Wen Huang,Dongxi Xiang,Congjun Wang,Qiyun Li,Xiangsong Wu,Wei Gong,Yun Liu,Rong Shao,Fatao Liu,Maolan Li,Luonan Chen,Yingbin Liu,Single-cell RNA-sequencing atlas reveals an MDK-dependent immunosuppressive environment in ErbB pathway-mutated gallbladder cancer,J Hepatol2021 Jun 22.
Guangxin Yao,Shuanggang Hu,Lu Yu,Yanfei Ru,Charlie Degui Chen,Qiang Liu,Yonglian Zhang,Genome-wide mapping of？in vivo？ERα binding sites in male mouse efferent ductules.,Endocrinology2017,00483
Juan Tang,Hui Zhang,Lingjuan He,Xiuzhen Huang,Yan Li,Wenjuan Pu,Wei Yu,Libo Zhang,Dongqing Cai,Kathy O Lui,Bin Zhou,Genetic Fate Mapping Defines the Vascular Potential of Endocardial Cells in the Adult Heart,Circ Res2018,Jan 26
Ke？Wang,Min？Shi,Hong？Cheng,Microinjection and Fluorescence In Situ Hybridization Assay for Studying mRNA Export in Mammalian Cells.,Methods Mol Biol.2017,1648:95-102
Yi Jacky Peng,Hua Yu,Xiaoxin Hao,Wenjie Dong,Xiujuan Yin,Minghui Lin,Junke Zheng,Bo O Zhou,Luteinizing hormone signaling restricts hematopoietic stem cell expansion during puberty,EMBO J2018 Jul 23
Meiyi Li, Chen Li, Weixin Liu, Conghui Liu, Jingru Cui, Qingrun Li, Hong Ni, Yingcheng Yang, Chaochao Wu, Chunlei Chen, Xing Zhen, Tao Zeng, Mujun Zhao, Lei Chen, Jiarui Wu, Rong Zeng, Luonan Chen.,Dysfunction of PLA2G6 and CYP2C44-associated network signals imminent carcinogenesis from chronic inflammation to hepatocellular carcinoma.,J Mol？Cell？Biol.2017,001-015
Yuejia Huang, Teng Li，Stephanie C.Ems-McClung,Claire E.Walczak, Claude Prigent, Xueliang Zhu, Xuemin Zhang,Yixian Zheng.,Aurora A activation in mitosis promoted by BuGZ,J？Cell？Biol
Qian Xiao,Jibo Wu,Weijia Wang,Shiyang Chen,Yingxia Zheng,Xiaoqing Yu,Katrina Meeth,Mahnaz Sahraei,Alfred L M Bothwel,Lieping Chen,Marcus Bosenberg,Jianfeng Chen,Veronika Sexl,Le Sun,Lin Li,Wenwen Tang,Dianqing Wu,DKK2 imparts tumor immunity evasion through β-catenin-independent suppression of cytotoxic immune-cell activation,Nat Med2018,Feb 12
Qing Li, Yanjing Li, Suming Yang, Shuo Huang, Meng Yan, Yifu Ding, Wei Tang, Xiwen Lou,Qi Yin, Zhanfei Sun, Lei Lu, Huijuan Shi, Hongyan Wang, Yong Chen，Jinsong Li,CRISPR–Cas9-mediated base-editing screening in mice identifies DND1 amino acids that are critical for primordial germ cell development,Nature Cell Biology2018 Oct 1
Jianshu Wang,Jiyun Chen,Guifen Wu,Hongling Zhang,Xian Du,Suli Chen,Li Zhang,Ke Wang,Jing Fan,Shuaixin Gao,Xudong Wu,Shouxiang Zhang,Bin Kuai,Peng Zhao,Binkai Chi,Lantian Wang,Guohui Li,Catherine C.L.Wong, Yu Zhou,Jinsong Li,Caihong Yun,Hong Cheng,NRDE2 negatively regulates exosome functions by inhibiting MTR4 recruitment and exosome interaction,Genes Dev2019 Mar 6
Weiping Li,Liguang Yang,Qiang He,Chaobo Hu,Linying Zhu,Xiaolong Ma,Xueyan Ma,Shujie Bao,Lu Li,Yingying Chen,Xing Deng,Xin Zhang,Jin Cen,Lei Zhang,Zhong Wang,Weifen Xie,Hong Li,Yixue Li,Lijian Hui,A Homeostatic Arid1a-Dependent Permissive Chromatin State Licenses Hepatocyte Responsiveness to Liver-Injury-Associated YAP Signaling,Cell Stem Cell2019 July 3

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