Representative Publications----Institute of Biochemistry and Cell Biology, Shanghai Institute for Biological Sciences, CAS

Research

Siyang Wu,Ruixiu Cao,Bangbao Tao,Ping Wu,Chao Peng,Hong Gao,Ji Liang,Weiwei Yang,Pyruvate Facilitates FACT-Mediated γH2AX Loading to Chromatin and Promotes the Radiation Resistance of Glioblastoma,Adv Sci2022 Jan 20.
Yajuan Zhang, Ming Zhao, Hong Gao, Guanzhen Yu, Yun Zhao, Feng Yao, Weiwei Yang,MAPK signalling-induced phosphorylation and subcellular translocation of PDHE1α promotes tumour immune evasion,Nat Metab2022 Mar 21.
Menghan Huang, Guixin Peng, Xueling Mao, Jintao Wang, Jingbo Zhou, Jianhui Zhang, Meirong Chen, Enduo Wang, Xiaolong Zhou,Molecular basis for human mitochondrial tRNA m3C modification by alternatively spliced METTL8,Nucleic Acids Res2022 Mar 31.
Maozhou Zhao, Dihang Lin, Heng Zuo, Huan Wei, Xin Wang, Lantao Gou, Mofang Liu,piRNA 3' uridylation facilitates the assembly of MIWI/piRNA complex for efficient target regulation in mouse male germ cells,Cell Res2022 Apr 15.
Jinlong Suo, Sihai Zou, Jinghui Wang, Yujiao Han, Lingli Zhang, Chenchen Lv, Bo Jiang, Qian Ren, Long Chen, Lele Yang, Ping Ji, Xianyou Zheng, Ping Hu, Weiguo Zou,The RNA-binding protein Musashi2 governs osteoblast-adipocyte lineage commitment by suppressing PPARγ signaling,Bone Res2022 Mar 17.
Liangqing Dong,Dayun Lu,Ran Chen,Youpei Lin,Hongwen Zhu,Zhou Zhang,Shangli Cai,Peng Cui,Guohe Song,Dongning Rao,Xinpei Yi,Yingcheng Wu,Nixue Song,Fen Liu,Yunhao Zou,Shu Zhang,Xiaoming Zhang,Xiaoying Wang,Shuangjian Qiu,Jian Zhou,Shisheng Wang,Xu Zhang,Yongyong Shi,Daniel Figeys,Li Ding,Pei Wang,Bing Zhang,Henry Rodriguez,Qiang Gao,Daming Gao,Hu Zhou,Jia Fan,Proteogenomic characterization identifies clinically relevant subgroups of intrahepatic cholangiocarcinoma,Cancer Cell2021 Dec 30.
Qin Hong,Wenyu Han,Jiawei Li,Shiqi Xu,Yifan Wang,Cong Xu,Zuyang Li,Yanxing Wang,Chao Zhang,Zhong Huang,Yao Cong,Molecular basis of receptor binding and antibody neutralization of Omicron,Nature2022 Feb 28.
Juan Tang,Huan Zhu,Xueying Tian,Haixiao Wang,Shaoyan Liu,Kuo Liu,Huan Zhao,Lingjuan He,Xiuzhen Huang,Zhao Feng,Zhangheng Ding,Ben Long,Yan Yan,Nicola Smart,Hui Gong,Qingming Luo,Bin Zhou,Extension of Endocardium-Derived Vessels Generate Coronary Arteries in Neonates,Circ Res2022 Jan 7.
Qin Xu,Chao Wang,Jiaxin Zhou,Zhimei Xu,Juan Gao,Pengfei Sui,Colum P. Walsh,Hongbin Ji,Guoliang Xu,Loss of TET reprograms Wnt signaling through impaired demethylation to promote lung cancer development,Proc Natl Acad Sci USA2022 Feb 3.
Lijun Wang,Xiuling You,Lingli Zhang,Changqing Zhang,Weiguo Zou,Mechanical regulation of bone remodeling,Bone Res2022 Feb 18.
Chenhua Wang,Ludi Zhang,Zhen Sun,Xiang Yuan,Baihua Wu,Jin Cen,Lei Cui,Kun Zhang,Chun Li,Jingqi Wu,Yajing Shu,Wenbin Sun,Jing Wang,Lijian Hui,Dedifferentiation-associated inflammatory factors of long-term expanded human hepatocytes exacerbate their elimination by macrophages during liver engraftment,Hepatology2022 Mar 1.
Xiang Gao,Xukai Ma,Xiang Li,Guowei Li,Chuxiao Liu,Jun Zhang,Ying Wang,Jia Wei,Jia Chen,Lingling Chen,Li Yang,Knockout of circRNAs by base editing back-splice sites of circularized exons,Genome Biol2022 Jan 10.
Fan Zhang,Qiyu Zeng,Hao Xu,Aining Xu,Dianjia Liu,Ningzhe Li,Yi Chen,Yi Jin,Chunhui Xu,Changzhou Feng,Yuanliang Zhang,Dan Liu,Na Liu,Yinyin Xie,Shanhe Yu,Hao Yuan,Kai Xue,Jingyi Shi,Tingxi Liu, Pengfei Xu,Weili Zhao,Yi Zhou,Lan Wang,Qiuhua Huang,Zhu Chen,Saijuan Chen,Xiaolong Zhou,Xiaojian Sun,Selective and competitive functions of the AAR and UPR pathways in stress-induced angiogenesis,Cell Discov2021 Oct 26.
Yiao Jiang,Jiayin Peng,Jiawen Song,Juan He,Man Jiang,Jia Wang,Liya Ma,Yuang Wang,Moubin Lin,Hailong Wu,Zhao Zhang,Dong Gao,Yun Zhao,Loss of Hilnc prevents diet-induced hepatic steatosis through binding of IGF2BP2,Nat Metab2021 Nov 8.
Hui Sophie Shu,Yiming Liam Liu,Xinyu Thomas Tang,Xinyi Shirley Zhang,Bin Zhou,Weiguo Zou,Bo O.Zhou,Tracing the skeletal progenitor transition during postnatal bone formation,Cell Stem Cell2021 Sep 8.
Chunyan Yi,Xiaoyu Sun,Yixiao Lin,Chenjian Gu,Longfei Ding,Xiao Lu,Zhuo Yang,Yaguang Zhang,Liyan Ma,Wangpeng Gu,Aidong Qu,Xu Zhou,Xiuling Li,Jianqing Xu,Zhiyang Ling,Youhua Xie,Hongzhou Lu,Bing Sun,Comprehensive mapping of binding hot spots of SARS-CoV-2 RBD-specific neutralizing antibodies for tracking immune escape variants,Genome Med2021 Oct 14.
Wendong Weng,Xiuxiu Liu,Kathy O Lui,Bin Zhou,Harnessing orthogonal recombinases to decipher cell fate with enhanced precision,Trends Cell Biol2021 Oct 15.
Junhao Fu,Qing Li,Xiaoyu Liu,Tianxiang Tu,Xiujuan Lv,Xidi Yin,Jineng Lv,Zongming Song,Jia Qu,Jinwei Zhang,Jinsong Li,Feng Gu,Human cell based directed evolution of adenine base editors with improved efficiency,Nat Commun2021 Oct 8.
Xinxin Zhu,Na Yang,Yu Yang,Feiyang Yuan,Dandan Yu,Yu Zhang,Zhaoqian Shu,Ning Nan,Hong Hu,Xiaoyan Liu,She Chen,Liming Sun,Huayi Wang,Spontaneous necroptosis and autoinflammation are blocked by an inhibitory phosphorylation on MLKL during neonatal development,Cell Res2021 Nov 2.
Yajuan Zhang,Hua Yu,Jie Zhang,Hong Gao,Siyao Wang,Shuxian Li,Ping Wei,Ji Liang,Guanzhen Yu,Xiongjun Wang,Xinxiang Li,Dawei Li,Weiwei Yang,Cul4A-DDB1-mediated monoubiquitination of phosphoglycerate dehydrogenase promotes colorectal cancer metastasis via increased S-adenosylmethionine,J Clin Invest2021 Nov 1.

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