Representative Publications----Institute of Biochemistry and Cell Biology, Shanghai Institute for Biological Sciences, CAS

Research

Liyong Zeng, Cheguo Cai, Shan Li, Wenjuan Wang, Yaping Li, Jiangye Chen,Xueliang Zhu*, Yi Arial Zeng*,Essential Roles of Cyclin Y-Like 1 and Cyclin Y in Dividing Wnt-Responsive Mammary Stem/Progenitor Cells,PLoS Genetics12(5): e1006055
Chang Xie,Xuemin Gong,Jie Luo,Boliang Li,Baoliang Song,AAV9-NPC1 significantly ameliorates Purkinje cell death and behavioral abnormalities in mouse NPC disease.,J Lipid Res.2017,58:512-518.
Xiwen Wang,Chuxiao Liu,Lingling Chen,Qiangfeng Cliff Zhang,RNA structure probing uncovers RNA structure-dependent biological functions,Nat Chem Boil2021 Jun 25.
Tengfei Ma, Yingjie Peng, Wei Huang,？Jianping Ding,Molecular mechanism of the allosteric regulation of the αγ heterodimer of human NAD-dependent isocitrate dehydrogenase.,Sci Rep2017,27:540-558
Xiangyuan Liu, Min Chen, Long Li, Liyan Gong, Hu Zhou and Daming Gao,ERK Kinases Phosphorylate Lin28a to Modulate P19 Cell Proliferation and Differentiation,J Biol Chem2017,292:3970-3976
Senlin Li, Ye Cui, Heng Liu, Lele Zhang, Xiaojie Zhang, Lindi Jiang,Chen Wang, Qin Zhou,The E3 ubiquitin ligase RNF185 facilitates the cGAS-mediated innate immune response,PLoS Pathog2017,13(3):e1006264
Chuanchao Zhang, Juan Liu, Qianqian Shi, Tao Zeng and Luonan Chen,Comparative network stratification analysis for identifying functional interpretable network biomarkers.,BMC Bioinformatics2017,18(Suppl 3):48
Meiyi Li, Chen Li, Weixin Liu, Conghui Liu, Jingru Cui, Qingrun Li, Hong Ni, Yingcheng Yang, Chaochao Wu, Chunlei Chen, Xing Zhen, Tao Zeng, Mujun Zhao, Lei Chen, Jiarui Wu, Rong Zeng, Luonan Chen.,Dysfunction of PLA2G6 and CYP2C44-associated network signals imminent carcinogenesis from chronic inflammation to hepatocellular carcinoma.,J Mol？Cell？Biol.2017,001-015
Zhenzheng Hu,Xiangyi Shi,Bowen Yu,Na Li,Ying Huang,Yongning He,Structural Insights into the pH-Dependent Conformational Change and Collagen Recognition of the Human Mannose Receptor.,Structure
Jing Xue, Hongwen Chen, Jian Wu, Miho Takeuchi, Haruna Inoue, Yanmei Liu, Hong Sun, Yong Chen,Junko Kanoh，Ming Lei.,Structure of the fission yeast S. pombe telomeric Tpz1-Poz1-Rap1 complex.,Cell Res2017,27:1503-1520
Lingjuan？He，and Bin？Zhou.,Cardiomyocyte proliferation: remove brakes and push accelerators,Cell Res？2017,27:959-960.
Hui Zhang,Xiuzhen Huang,Kuo Liu,Juan Tang,Lingjuan He,Wenjuan Pu,Qiaozhen Liu,Yan Li,Xueying Tian,Yue Wang,Libo Zhang,Ying Yu,Hongyan Wang,Ronggui Hu,Fengchao Wang,Ting Chen,Qingdong Wang,Zengyong Qiao,Li Zhang,Kathy O Lui,Bin Zhou.,Fibroblasts in an endocardial fibroelastosis disease model mainly originate from mesenchymal derivatives of epicardium,Cell Res？2017,27:1157-1177
Peng Yuan, Xiao-Hong He, Ye-Fei Rong, Jing Cao4,Yong Li, Yun-Ping Hu, Yingbin Liu, Dangsheng Li, Wenhui Lou and Mo-Fang Liu,KRAS/NF-kB/YY1/miR-489 Signaling Axis Controls Pancreatic Cancer Metastasis,Cancer Research77（1）
Lu L, Lin CD, Yan ZJ, Wang S, Zhang YH, Wang SH, Wang JL, Liu C, Chen JF*,Kindlin-3 is essential for resting α4β1 integrin-mediated firm cell adhesion under shear flow conditions,J Biol Chem.
Li X, Cui J, Yu Y, Li W, Hou Y, Wang X, Qin D, Zhao C, Yao X, Zhao J, Pei G,Traditional Chinese nootropic medicine Radix Polygalae and its active constituent Onjisaponin B reduce β-amyloid production and improve cognitive impairment,PLoS One
Wu W, Shi X, Xu C*,Regulation of T cell signalling by membrane lipids,Nature Reviews Immunology
Xiangdong Lv, Zhijun Han, Hao Chen, Bo Yang, Xiaofeng Yang, Yuanxin Xia, Chenyu Pan, Lin Fu, Shuo Zhang, Hui Han, Min Wu, Zhaocai Zhou, Lei Zhang, Lin Li, Gang Wei, Yun Zhao,A Positive Role for Polycomb in Transcriptional Regulation via H4K20me1,Cell Res.26: 529-542
Jiao Yang, Hong Peng, Xiaoduo Xie, Ronggui Hu,SQSTM1/p62 (sequestosome 1) senses cellular ubiquitin stress through E2-mediated ubiquitination.,Autophagy
Chenyu Pan,Yue Xiong,Xiangdong Lv,Yuanxin Xia,Shuo Zhang,Hao Chen,Jialin Fan,Wenqing Wu,Feng Liu, Hailong Wu,Zhaocai Zhou,Lei Zhang,Yun Zhao,UbcD1 regulates Hedgehog signaling by directly modulating Ci ubiquitination and processing,EMBO Rep
Min Cong,Yuan Wang,Yang Yang,Cheng Lian,Xueqian Zhuang,Xiaoxun Li,Peiyuan Zhang,Yingjie Liu,Jun Tang,Qifeng Yang,Xue Zhang,Hua Xiong,Ronggui Hu,Guohong Hu,MTSS1 suppresses mammary tumor-initiating cells by enhancing RBCK1-mediated p65 ubiquitination,Nature Cancer2020 Jan 20.

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