Representative Publications----Institute of Biochemistry and Cell Biology, Shanghai Institute for Biological Sciences, CAS

Research

Ye Tao,Chen Zhong,Junjun Zhu,Shutong Xu,Jianping Ding.,Structural and mechanistic insights into regulation of HBO1 histone acetyltransferase activity by BRPF2,Nucleic Acids Res.2017,45:5707-5719
Xingxing Xu, Chuanyin Li, Xiaobo Gao, Kun Xia, Hui Guo, Yali Li, Zijian Hao, Lei Zhang, Daming Gao, Chenfan Xu, Huatai Xu, Zhiqi Xiong, Zilong Qiu, Ling Mei, Xiaoduo Xie, Kangcheng Ruan,Ronggui Hu.,Excessive UBE3A Dosage Impairs Retinoic Acid Signaling and Synaptic Plasticity in Autism Spectrum Disorders.,Cell Res2018,28:48-68
Linlin Zhao,Shuqing Wang,Qianli Zhu,Bin Wu,Zhijun Liu,Bo OuYang,James J.Chou,Specific Interaction of the Human Mitochondrial Uncoupling Protein 1 with Free Long-Chain Fatty Acid.,Structure2017,26:30220-24.
Gaoxiang Zhao,Liyan Gong,Dan Su,Yujuan Jin,Chenchen Guo,Meiting Yue,Shun Yao,Zhen Qin,Yi Ye,Ying Tang, Qibiao Wu,Jian Zhang,Binghai Cui,Qiurong Ding,Hsinyi Huang,Liang Hu,Yuting Chen,Peiyuan Zhang,Guohong Hu,Luonan Chen,Kwok-Kin Wong,Daming Gao,Hongbin Ji,Cullin5 deficiency promotes small-cell lung cancer metastasis by stabilizing integrin β1,J Clin Invest2019 Jan 28
Suli Chen,Ruijia Wang,Dinghai Zheng,Heng Zhang,Xingya Chang,Ke Wang,Wencheng Li,Jing Fan,Bin Tian,Hong Cheng,The mRNA Export Receptor NXF1 Coordinates Transcriptional Dynamics, Alternative Polyadenylation, and mRNA Export,Mol Cell2019 Feb 25
Yifei Zhou,Xueqing Wang,Mengjiao Song,Zhidong He,Guizhong Cui,Guangdun Peng,Christoph Dieterich,Adam Antebi,Naihe Jing,Yidong Shen,A secreted microRNA disrupts autophagy in distinct tissues of Caenorhabditis elegans upon ageing,Nat Commun2019 Oct 23
Feng Li,Peng Yuan,Ming Rao,Chunhui Jin,Wei Tang,Yefei Rong, Yunping Hu,Fengjuan Zhang,Tao Wei,Qi Yin,Tingbo Liang,Ligang Wu,Jinsong Li,Dangsheng Li,Yingbin Liu,Wenhui Lou,Shuang Zhao,Mofang Liu,piRNA-independent function of PIWIL1 as a co-activator for anaphase promoting complex/cyclosome to drive pancreatic cancer metastasis,Nat Cell Biol2020 Mar 16.
Chao Wang, Meng-Xin Yin, Wei Wu, Liang Dong, Shimin Wang, Yi Lu, Jinjin Xu, Wenqing Wu, Sheng Li, and Yun Zhao Lei Zhang,Taiman acts as a co-activator of Yorkie in the Hippo pathway to promote tissue growth and intestinal regeneration.,Cell Discovery2016,2,16006
Haineng Xu, Jiasheng Mu, Jing Xiao, Xiangsong Wu, Maolan Li, Tianrun Liu, Xinyuan Liu,CD24 negative lung cancer cells, possessing partial cancer stem cell properties, cannot be considered as cancer stem cells,Am J Cancer Res.6(1): 51-60
Fangfang Jiang, Falong Lu, Peixue Li, Wei Liu, Lu Zhao, Qifu Wang, Xiaofeng Cao, Lei Zhang, and Yong Q. Zhang,Drosophila homolog of FMRP maintains genome integrity by interacting with Piwi.,Journal of Genetics and Genomics43:11-24
Xiongjun Wang,Yunbo Qiao,Minzhe M.Xiao,Lingbo Wang,Jun Chen,Wenjian Lv,Li Xu,Yan Li,Yumei Wang,Mingdian Tan,Chao Huang,Jinsong Li,Ting C.Zhao,Zhaoyuan Hou,Naihe Jing,and Y.Eugene Chin,Opposing Roles of Acetylation？and？Phosphorylation in LIFR-Dependent Self-Renewal Growth Signaling in Mouse Embryonic Stem Cells.,Cell？Rep.2017,18:933-946.
He Xu,Chunmei Yue,Ting Zhang,Yuanyuan Li,Ao Guo,Jiaoyang Liao,Gang Pei,Jinsong Li,Naihe Jing,Derivation of Haploid Neurons from Mouse Androgenetic Haploid Embryonic Stem Cells,Neurosci Bull2017,33:361-364
Lu Song, Jun Chen, Guangdun Peng, Ke Tang, NaiheJing*.,Dynamic Heterogeneity of Brachyury in Mouse Epiblast Stem Cells Mediates Distinct Respond to Extrinsic BMP Signaling.,J. Biol. Chem.291(29):15212-15225
Xu Xiao, Jingjie Tang, Chao Peng, Yan Wang, Lin Fu, Zhiping Qiu, Yue Xiong, Lianfang Yang, Haiwei Cui, Xiaolong He,Lei Yin,Wei Qi,Catherine C.L.Wong,Yun Zhao,Boliang Li, Wenwei Qiu,Baoliang Song,Cholesterol Modification of Smoothened Is Required for Hedgehog Signaling.,Mol Cell2017,66:154-162
Shimin Wang, Yi Lu, Meng-Xin Yin, Chao Wang, Wei Wu, Jinhui Li, Wenqing Wu, Ling Ge, Lianxin Hu, Yun Zhao, Lei Zhang,Importin α1 mediates Yorkie nuclear import via N-terminal non-canonical nuclear localization signal.,The Journal of Biological Chemistry2016,291(15):7926-37
Xing Liu, Chen Wang,The emerging roles of the STING adaptor protein in immunity and diseases.,ImmunologyVol 147: 285-291
Kirill Oxenoid, Ying Dong, Chan Cao, Tanxing Cui, Yasemin Sancak, Andrew L. Markhard, Zenon Grabarek, Liangliang Kong, Zhijun Liu, Bo Ouyang, Yao Cong, Vamsi K. Mootha & James J. Chou,Architecture of the Mitochondrial Calcium Uniporter,Nature533(7602), 269-273
Chen Chu,Lu Yu,Bin Wu,Li Ma,Lantao Gou,Miao He,Yunli Guo,Zhitong Li,Wei Gao,Huijuan Shi,Mofang Liu,Hongyan Wang,Charlie Degui Chen,Jo？l R.Drevet,Yuchuan Zhou,Yonglian Zhang.,A sequence of 28？S rRNA-derived small RNAs is enriched in mature sperm？andvarious somatic tissues？and？possibly associates with inflammation.,J Mol Cell Biol.2017,9:256-259
Liting Zheng,Longyong Xu.Qing Xu,Lu Yu,Danfeng Zhao,Pu Chen,Wei Wang,Yiqin Wang,Gang Han,Charlie Degui Chen,Utx loss causes myeloid transformation,Leukemia2018 Feb 20
Yan Tang, Yazhen Hong, Huajun Bai, Qiang Wu, Charlie Degu Chen,Jingyu Lang, Kenneth R.Boheler,and Huangtian Yang,PHF8 regulates mesodermal and cardiac differentiation of embryonic stem cells through mediating the histone demethylation of pmaip1,Stem Cells.2016,34:1527-40

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