Representative Publications----Institute of Biochemistry and Cell Biology, Shanghai Institute for Biological Sciences, CAS

Research

Xiaoman Wang,Yiyue Zhao,Jian Zhang,Yong Chen.,Structural basis for DAXX interaction with ATRX.,Protein Cell.10,767-771.
Lingbo Wang, Minyin Li, Chao Qu1, Wanying Miao, Qi Yin, Jiaoyang Liao, Huateng Cao,Min Huang, Kai Wang, Erwei Zuo, Guangdun Peng, Shuxin Zhang, Guodong Chen, Qing Li, Ke Tang,Qian Yu, Zhoujie Li, Catherine CL Wong, Guoliang Xu, Naihe Jing, Xiang Yu, Jinsong Li.,CRISPR-Cas9-mediated genome editing in one blastomere of two-cell embryos reveals a novel Tet3 function in regulating neocortical development.,Cell Res2017,27:815-829
Yujiao Han,Xiuling You,Wenhui Xing,Zhong Zhang,Weiguo Zou,Paracrine and endocrine actions of bone-the functions of secretory proteins from osteoblasts, osteocytes, and osteoclasts,Bone Res2018 May 24
Xiaoxi Li,Yanli Zhang,Liting Zheng,Mingxian Liu,Charlie Degui Chen,Hai Jiang,UTX is an escape from X-inactivation tumor-suppressor in B cell lymphoma,Nat Commun2018,9:2720
Feng Zhang,Yifan Liu,Zhiwen Zhang,Jie Li,Yi Wan,Liying Zhang,Yangmei Wang,Xia Li,Yuqiao Xu,Xin Fu,Xiumin Zhang,Ming Zhang,Zhekai Zhang,Jing Zhang,Qingguo Yan,Jing Ye,Zhe Wang,Charlie Degui Chen,Wei Lin,Qing Li,5-hydroxymethylcytosine loss is associated with poor prognosis for patients with WHO grade II diffuse astrocytomas.,Sci Rep.2016,6:20882
Xiaohua Ye, Chen Fan, Zhiqiang Ku, Teng Zuo, Liangliang Kong, Chao Zhang, Jinping Shi, Qingwei Liu, Tan Chen, Yingyi Zhang, Wen Jiang, Linqi Zhang, Zhong Huang, Yao Cong,Structural Basis for Recognition of Human Enterovirus 71 by a Bivalent Broadly Neutralizing Monoclonal Antibody,PLoS Pathogen12(3):e1005454
XiuminYan and Xueliang Zhu,PP2A in meiotic oocytes.,Cell Cycle15(15):1950-1951
Pei Chen, Rui Liu, Yongjun Li, Luonan Chen,Detecting critical state before phase transition of complex biological systems by hidden Markov model.,Bioinformatics
Shenda Hou, Shiyu Zhou, Zhen Qin, Liu Yang, Xiangkun Han, Shun Yao, Hongbin Ji,Evidence, Mechanism, and Clinical Relevance of the Transdifferentiation from Lung Adenocarcinoma to Squamous Cell Carcinoma.,Am J Pathol2017,187(5):954-962
Zhubing Shi, Feng He, Min Chen, Long Hua, Wenjia Wang, Shi Jiao, Zhaocai Zhou,DNA-binding mechanism of the Hippo pathway transcription factor TEAD4.,Oncogene2017,36:4362-4369
Meiyi Li, Chen Li, Weixin Liu, Conghui Liu, Jingru Cui, Qingrun Li, Hong Ni, Yingcheng Yang, Chaochao Wu, Chunlei Chen, Xing Zhen, Tao Zeng, Mujun Zhao, Lei Chen, Jiarui Wu, Rong Zeng, Luonan Chen.,Dysfunction of PLA2G6 and CYP2C44-associated network signals imminent carcinogenesis from chronic inflammation to hepatocellular carcinoma.,J Mol？Cell？Biol.2017,001-015
Ye Zhang,Hao Shen,Haifeng Liu,Haiyun Feng,Yan Liu,Xiaoyan Zhu，Xiaolong Liu.,Arp2/3 complex controls T cell homeostasis by maintaining surface TCR levels via regulating TCR+ endosome trafficking,Sci Rep2017,7:8952.
Jingbo Zhou,Yong Wang,Qiyu Zeng,Shixin Meng,Enduo Wang,Xiaolong Zhou,Molecular basis for t6A modification in human mitochondria,Nucleic Acids Res2020 Feb 12.
Daisong Wang,Jingqiang Wang,Lanyue Bai,Hong Pan,Hua Feng,Hans Clevers,Yi Arial Zeng,Long-Term Expansion of Pancreatic Islet Organoids from Resident Procr+ Progenitors,Cell2020 Mar 19.
Jing Xu, Pei-xue Li, Jun Wu, Yi-jun Gao, Meng-xin Yin, Ye Lin, Ming Yang, Dong-ping Chen, Hai-peng Sun, Zeng-bo Liu, Xiang-chen Gu, Hong-ling Huang, Li-li Fu, Hui-min Hu, Liang-liang He, Wen-qing Wu, Zhao-liang Fei, Hong-bin Ji, Lei Zhang*, Chang-Lin Mei*,Involvement of the Hippo Pathway in Regeneration and Fibrogenesis after Ischemic Acute Kidney Injury: YAP is the Key Effector.,Clinical Science2016,130:349-363
Wei Chen, Senlin Li, Huansha Yu, Xing Liu, Lulu Huang, Qiang Wang, Heng Liu, Ye Cui, Yijun Tang, Peng Zhang, Chen Wang,ER Adaptor SCAP Translocates and Recruits IRF3 to Perinuclear Microsome Induced by Cytosolic Microbial DNAs.,PLOS PathogensVol 12(2): e1005462
Guang Li, Adele Xu, Sopheak Sim, James R. Priest, Xueying Tian4, Tooba Khan, Thomas Quertermous, Bin Zhou, Philip S. Tsao, Stephen R. Quake, Sean M. Wu,Transcriptomic Profiling Maps Anatomically Patterned Subpopulations among Single Embryonic Cardiac Cells,Developmental Cell21 November 2016, Pages 491–507
Chang Xie, Ya-Ping Zhang, Lu Song, Jie Luo, Wei Qi, Jialu Hu, Danbo Lu, Zhen Yang, Jian Zhang, Jian Xiao, Bin Zhou, Jiu-Lin Du, Naihe Jing, Yong Liu, Yan Wang, Bo-Liang Li, Bao-Liang Song, Yan Yan,Genome editing with CRISPR/Cas9 in postnatal mice corrects PRKAG2 cardiac syndrome,Cell Research26:1099-1111
Jing Xia$, Rong Wang$, Tianlong Zhang*, and Jianping Ding*,Structural insight into the arginine binding specificity of CASTOR1 in amino acid-dependent mTORC1 signaling,Cell Discovery2: 16035
Xu L#, Xia M#, Guo J#, Sun X#, Li H, Xu C, Gu X, Zhang H, Yi J, Fang Y, Xie H, Wang J, Shen Z, Xue B, Sun Y, Meckel T, Chen Y, Hu Z, Li Z*, Xu C*, Gong H*, Liu W*,Impairment on the lateral mobility induced by structural changes underlies the functional deficiency of the lupus-associated polymorphism FcγRIIB-T232,The Journal of Experimental Medicine

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