Representative Publications----Institute of Biochemistry and Cell Biology, Shanghai Institute for Biological Sciences, CAS

Research

Xiaohang Li, Qinying Wang, Tingting Hu, Ying Wang, Jian Zhao, Jing Lu，Gang Pei.,A tricyclic antidepressant, amoxapine, reduces amyloid-β generation through multiple serotonin receptor 6-mediated targets.,Sci Rep.2017,7(1):4983.
Naoe T.Nihira, Kohei Ogura, Kouhei Shimizu, Brian J.North1,Jinfang Zhang,Daming Gao,Hiroyuki Inuzuka, Wenyi Wei,Acetylation-dependent regulation of MDM2 E3 ligase activity dictates its oncogenic function.,Sci Signal.？？2017,10:i8026
Qingrun Li, Yansheng Liu, Rong Zeng,Shotgun？and？Targeted Plasma Proteomics to Predict Prognosis of Non-SmallCell？Lung Cancer.,Methods Mol Biol.2017,1619:385-394
Xiangpeng Sheng,Qing You,Hongnian Zhu,ZeNan Chang,Qingrun Li,Haifeng Wang,Chen Wang,Hongyan Wang,Lijian Hui,Chongtao Du,Xiaoduo Xie,Rong Zeng,Anning Lin,Dongfang Shi,Kangcheng Ruan,Jinghua Yan,George Fu Gao,Feng Shao,Ronggui Hu.,Bacterial effector NleL promotes enterohemorrhagic E. coli-induced attaching and effacing lesions by ubiquitylating and inactivating JNK.,PLoS Pathog2017,13:e1006534
Li Yang and Lingling Chen.,Enhancing the RNA engineering toolkit.,Science2017,358,996-997.
Xiang Sun,Yu Cui,Haiyun Feng,Haifeng Liu,Xiaolong Liu,TGF-β signaling controls Foxp3 methylation and T reg cell differentiation by modulating Uhrf1 activity,J Exp Med2019 Sep 12
Yao Chen,Ruitu Lyu,Bowen Rong,Yuxuan Zheng,Zhen Lin,Ruofei Dai,Xi Zhang,Nannan Xie,Siqing Wang,Fuchou Tang,Fei Lan,Minghan Tong,Refined spatial temporal epigenomic profiling reveals intrinsic connection between PRDM9-mediated H3K4me3 and the fate of double-stranded breaks,Cell Res2020 Feb 11.
Quanquan Ji,Zhipeng Fang,Qing Ye,Chengwu Chi,Enduo Wang.,Self-protective responses to norvaline-induced stress in a leucyl-tRNA synthetase editing-deficient yeast strain.,Nucleic Acids Res2017,45:7367-7381
Biwei Yang,Meiyi Li,Wenqing Tang,Weixin Liu,Si Zhang,Luonan Chen,Jinglin Xia,Dynamic network biomarker indicates pulmonary metastasis at the tipping point of hepatocellular carcinoma,Nat Commun2018,9:678
Xiaoguang Liu,Wei Wei, Yuting Liu, Xueli Yang, Jian Wu, Yang Zhang, Qiao Zhang, Tieliu Shi,James X Du, Yingming Zhao, Ming Lei, Jinqiu Zhou,Jiwen Li,Jiemin Wong,MOF as an evolutionarily conserved histone crotonyltransferase and transcriptional activation by histone acetyltransferase-deficient and crotonyltransferase-competent CBP/p300,Cell Discovery2017,3:17016
Xiaoping Liu, Yuetong Wang, Hongbin Ji, Kazuyuki Aihara, Luonan Chen,Personalized characterization of diseases using sample-specific networks.,Nucleic Acids Research
Jingyao Zhao, Xufeng Chen, Guangrong Song, Jiali Zhang, Haifeng Liu, Xiaolong Liu,Uhrf1 controls the self-renewal versus differentiation of hematopoietic stem cells by epigenetically regulating the cell-division modes,Proc Natl Acad Sci U S Adoi:10.1073／pnas.1612967114
Lingling Chen,The expanding regulatory mechanisms and cellular functions of circular RNAs,Nat Rev Mol Cell Biol2020 May 4.
Qing Cai , Yuanyuan Li , Jianxin Mao and Gang Pei,Neurogenesis-Promoting Natural Product α-Asarone Modulates Morphological Dynamics of Activated Microglia. Front,Cell. Neurosci.
Rong Wang, Zhijing Wang, Tianlong Zhang*, and Jianping Ding*,Structural basis for targeting BIG1 to Golgi apparatus through interaction of its DCB domain with Arl1,J. Mol. Cell Biol.8: 459-461
Siwei Luo,Zhi Liang,Jiarui Wu,Simultaneously measuring multiple protein interactions and their correlations in a cell by Protein-interactome Footprinting.,Sci Rep2017,7:45169
Jingzheng Li,Yafang Shang,Lin Wang,Bo Zhao,Chunli Sun,Jiali Li,Siling Liu,Cong Li,Min Tang,Feilong Meng,Ping Zheng,Genome integrity and neurogenesis of postnatal hippocampal neural stem/progenitor cells require a unique regulator Filia,Sci Adv2020 Oct 28.
Hou S, Han X, Ji H*.,Squamous Transition of Lung Adenocarcinoma and Drug Resistance.,Trends in Cancer2 (9).
Yong Wang, Xiao-Long Zhou, Zhi-Rong Ruan, Ru-Juan Liu, Gilbert Eriani, and En-Duo Wang,A human disease-causing point mutation in mitochondrial threonyl-tRNA synthetase induces both structural andfunctional defects,J. Biol. Chem.291(12), 6507-6520
Dongqing Guo1,？, Ming Lu2,？, Xihan Hu1,？, Jiajia Xu1, Guangjing Hu1, Ming Zhu1, Xiaowei Zhang1, Qin Li1, Catherine C. Y. Chang3, Tayuan Chang3, Baoliang Song1,4, Ying Xiong1, and Boliang Li1,*,Low-level expression of human ACAT2 gene in monocytic cells is regulated by the C/EBP transcription factors,Acta Biochim Biophys Sin

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