Representative Publications----Institute of Biochemistry and Cell Biology, Shanghai Institute for Biological Sciences, CAS

Research

Zhubing Shi, Feng He, Min Chen, Long Hua, Wenjia Wang, Shi Jiao, Zhaocai Zhou,DNA-binding mechanism of the Hippo pathway transcription factor TEAD4.,Oncogene2017,36:4362-4369
Meiyi Li, Chen Li, Weixin Liu, Conghui Liu, Jingru Cui, Qingrun Li, Hong Ni, Yingcheng Yang, Chaochao Wu, Chunlei Chen, Xing Zhen, Tao Zeng, Mujun Zhao, Lei Chen, Jiarui Wu, Rong Zeng, Luonan Chen.,Dysfunction of PLA2G6 and CYP2C44-associated network signals imminent carcinogenesis from chronic inflammation to hepatocellular carcinoma.,J Mol？Cell？Biol.2017,001-015
Ye Zhang,Hao Shen,Haifeng Liu,Haiyun Feng,Yan Liu,Xiaoyan Zhu，Xiaolong Liu.,Arp2/3 complex controls T cell homeostasis by maintaining surface TCR levels via regulating TCR+ endosome trafficking,Sci Rep2017,7:8952.
Jingbo Zhou,Yong Wang,Qiyu Zeng,Shixin Meng,Enduo Wang,Xiaolong Zhou,Molecular basis for t6A modification in human mitochondria,Nucleic Acids Res2020 Feb 12.
Daisong Wang,Jingqiang Wang,Lanyue Bai,Hong Pan,Hua Feng,Hans Clevers,Yi Arial Zeng,Long-Term Expansion of Pancreatic Islet Organoids from Resident Procr+ Progenitors,Cell2020 Mar 19.
Jing Xu, Pei-xue Li, Jun Wu, Yi-jun Gao, Meng-xin Yin, Ye Lin, Ming Yang, Dong-ping Chen, Hai-peng Sun, Zeng-bo Liu, Xiang-chen Gu, Hong-ling Huang, Li-li Fu, Hui-min Hu, Liang-liang He, Wen-qing Wu, Zhao-liang Fei, Hong-bin Ji, Lei Zhang*, Chang-Lin Mei*,Involvement of the Hippo Pathway in Regeneration and Fibrogenesis after Ischemic Acute Kidney Injury: YAP is the Key Effector.,Clinical Science2016,130:349-363
Wei Chen, Senlin Li, Huansha Yu, Xing Liu, Lulu Huang, Qiang Wang, Heng Liu, Ye Cui, Yijun Tang, Peng Zhang, Chen Wang,ER Adaptor SCAP Translocates and Recruits IRF3 to Perinuclear Microsome Induced by Cytosolic Microbial DNAs.,PLOS PathogensVol 12(2): e1005462
Guang Li, Adele Xu, Sopheak Sim, James R. Priest, Xueying Tian4, Tooba Khan, Thomas Quertermous, Bin Zhou, Philip S. Tsao, Stephen R. Quake, Sean M. Wu,Transcriptomic Profiling Maps Anatomically Patterned Subpopulations among Single Embryonic Cardiac Cells,Developmental Cell21 November 2016, Pages 491–507
Chang Xie, Ya-Ping Zhang, Lu Song, Jie Luo, Wei Qi, Jialu Hu, Danbo Lu, Zhen Yang, Jian Zhang, Jian Xiao, Bin Zhou, Jiu-Lin Du, Naihe Jing, Yong Liu, Yan Wang, Bo-Liang Li, Bao-Liang Song, Yan Yan,Genome editing with CRISPR/Cas9 in postnatal mice corrects PRKAG2 cardiac syndrome,Cell Research26:1099-1111
Jing Xia$, Rong Wang$, Tianlong Zhang*, and Jianping Ding*,Structural insight into the arginine binding specificity of CASTOR1 in amino acid-dependent mTORC1 signaling,Cell Discovery2: 16035
Xu L#, Xia M#, Guo J#, Sun X#, Li H, Xu C, Gu X, Zhang H, Yi J, Fang Y, Xie H, Wang J, Shen Z, Xue B, Sun Y, Meckel T, Chen Y, Hu Z, Li Z*, Xu C*, Gong H*, Liu W*,Impairment on the lateral mobility induced by structural changes underlies the functional deficiency of the lupus-associated polymorphism FcγRIIB-T232,The Journal of Experimental Medicine
Andrés Palencia, Ru-Juan Liu, Maria Lukarska, Jiri Gut, Alexandre Bougdour, Bastien Touquet, En-Duo Wang, Xianfeng Li, M. R. K. Alley, Yvonne R. Freund, Philip J. Rosenthal, Mohamed-Ali Hakimi, Stephen Cusack,Cryptosporidium and Toxoplasma Parasites Are Inhibited by aBenzoxaborole Targeting Leucyl-tRNA Synthetase,Antimicrobial Agents and Chemotherapy
Liyun Yue, Lu Li, Dan Li, Zhuo Yang, Shuai Han, Ming Chen, Shujue Lan, Xiaojun Xu, Lijian Hui,High-throughput screening for Survivin and Borealin interaction inhibitors in hepatocellular carcinoma.,Biochem Biophys Res Commun.2017,484:642-647
Xiaohang Li, Qinying Wang, Tingting Hu, Ying Wang, Jian Zhao, Jing Lu，Gang Pei.,A tricyclic antidepressant, amoxapine, reduces amyloid-β generation through multiple serotonin receptor 6-mediated targets.,Sci Rep.2017,7(1):4983.
Naoe T.Nihira, Kohei Ogura, Kouhei Shimizu, Brian J.North1,Jinfang Zhang,Daming Gao,Hiroyuki Inuzuka, Wenyi Wei,Acetylation-dependent regulation of MDM2 E3 ligase activity dictates its oncogenic function.,Sci Signal.？？2017,10:i8026
Qingrun Li, Yansheng Liu, Rong Zeng,Shotgun？and？Targeted Plasma Proteomics to Predict Prognosis of Non-SmallCell？Lung Cancer.,Methods Mol Biol.2017,1619:385-394
Xiangpeng Sheng,Qing You,Hongnian Zhu,ZeNan Chang,Qingrun Li,Haifeng Wang,Chen Wang,Hongyan Wang,Lijian Hui,Chongtao Du,Xiaoduo Xie,Rong Zeng,Anning Lin,Dongfang Shi,Kangcheng Ruan,Jinghua Yan,George Fu Gao,Feng Shao,Ronggui Hu.,Bacterial effector NleL promotes enterohemorrhagic E. coli-induced attaching and effacing lesions by ubiquitylating and inactivating JNK.,PLoS Pathog2017,13:e1006534
Li Yang and Lingling Chen.,Enhancing the RNA engineering toolkit.,Science2017,358,996-997.
Xiang Sun,Yu Cui,Haiyun Feng,Haifeng Liu,Xiaolong Liu,TGF-β signaling controls Foxp3 methylation and T reg cell differentiation by modulating Uhrf1 activity,J Exp Med2019 Sep 12
Yao Chen,Ruitu Lyu,Bowen Rong,Yuxuan Zheng,Zhen Lin,Ruofei Dai,Xi Zhang,Nannan Xie,Siqing Wang,Fuchou Tang,Fei Lan,Minghan Tong,Refined spatial temporal epigenomic profiling reveals intrinsic connection between PRDM9-mediated H3K4me3 and the fate of double-stranded breaks,Cell Res2020 Feb 11.

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