Representative Publications----Institute of Biochemistry and Cell Biology, Shanghai Institute for Biological Sciences, CAS

Research

Shanshan Yan, Hongbo Shen, Qiaoshi Lian, Wenlong Jin, Ronghua Zhang, Xuan Lin, Wangpeng Gu, Xiaoyu Sun, Guangxun Meng, Zhigang Tian, Zheng W. Chen and Bing Sun,Deficiency of the AIM2-ASC Signal Uncovers the STING-Driven Overreactive Response of Type I IFN and Reciprocal Depression of Protective IFN-γ Immunity in Mycobacterial Infection.,J Immunol.
Yang Q, Lin J, Liu M, Li R, Tian B, Zhang X, Xu B, Liu M, Zhang X, Li Y, Shi H*, Wu L*,Highly Sensitive Sequencing Reveals Dynamic Modifications and Activities of Small RNAs in Mouse Oocytes and Early Embryos,Science Advances2(6): e1501482
Yuhan Zhang,Weiwei Liu,Ronghong Li,Jiaqi Gu,Ping Wu,Chao Peng,Jinbiao Ma,Ligang Wu,Yang Yu,Ying Huang,Structural insights into the sequence-specific recognition of Piwi by Drosophila Papi,Proc Natl Acad Sci USA2018,115:3374-3379
Wang C, Zeng X, Zhou Z, Zhao J, Pei G,β-arrestin-1 contributes to brown fat function and directly interacts with PPARα and PPARγ,Scientific Reports
Zhongfei Li, Bin Li, Jian Liu, Zhihao Guo, Yuhao Liu, Yan Li, Wen-Hui Shen, Ying Huang, Hai Huang, Yijing Zhang, Aiwu Dong,Transcription factors AS1 and AS2 interact with LHP1 to repress KNOX genes in Arabidopsis,J. Integr Plant Biology58, 959-970
Xue Y, Hou S, Ji H, Han X.,Evolution from genetics to phenotype: reinterpretation of NSCLC plasticity, heterogeneity, and drug resistance,Protein Cell
Wenting Zhu,Jiaxin Li,Rui Zhang,Yixiang Cai,Changwan Wang,Shishi Qi,She Chen,Xiaozhen Liang,Nan Qi,Fajian Hou,TRAF3IP3 mediates the recruitment of TRAF3 to MAVS for antiviral innate immunity,EMBO J2019 Aug 7
Chen Zhong,Jinlong Shen,Huibing Zhang,Guangyi Li,Senlin Shen,Fang Wang,Kuan Hu,Longxing Cao,Yongning He,Jianping Ding.,Cbln1 and Cbln4 Are Structurally Similar but Differ in GluD2 Binding Interactions,Cell Rep.2017,20:2328-2340.
Chunyi Hu, Rekha Rai, Chenhui Huang, Cayla Broton, Juanjuan Long, Ying Xu, Jing Xue, Ming Lei, Sandy Chang，Yong Chen.,Structural and functional analyses of the mammalian TIN2-TPP1-TRF2 telomeric complex.,Cell Res2017,27:1485-1502
Leilei Jiang,Wei Xue,Junye Hong,Junting Zhang,Minjun Li,Shaoning Yu,Jianhua He,Hongyu Hu,The N-terminal dimerization is required for TDP-43 splicing activity,Sci Rep2017,7:6196
Hongli Hu,Wenwei Zhu,Jun Qin,Min Chen,Liyan Gong,Long Li,Xiangyuan Liu,Yongzhen Tao,Huiyong Yin,Hu Zhou,Lisha Zhou,Dan Ye,Qinghai Ye,Daming Gao,Acetylation of PGK1 promotes liver cancer cell proliferation and tumorigenesis,Hepatology2017,65:515-528
Chao Zheng, Yuetong Wang, Liu Yang, Shuhua Zhou, Yijun Gao, Fuming Li, Yan Feng, Zuoyun Wang, Lixing Zhan, Qin Yan, Xueliang Zhu, Kwok-Kin Wong, Zhengjun Chen，Hongbin Ji.,Cell Division Cycle 42 plays a Cell type-Specific role in Lung Tumorigenesis,Sci Rep2017,7:10407.
Xianlong Fang,Dongmei Yang,Hongping Luo,Shuai Wu,Wenjie Dong,Jing Xiao,Sujing Yuan,Aimin Ni,Kangjian Zhang,Xinyuan Liu,Liang Chu.,SNORD126 promotes HCC and CRC cell growth by activating the PI3K-AKT pathway through FGFR2.,J Mol Cell Biol.2017,9:243-255
Lan He, Wangpeng Gu, Meng Wang, Xiaoyan Chang, Xiaoyu Sun, Yuan Zhang, Xuan Lin,Chenghua Yan, Weiguo Fan, Pan Su, Yanming Wang, Chunyan Yi, Guomei Lin, Li Li, Yu Jiang, Junxia Lu,Chen Dong, Haikun Wang, Bing Sun,Extracellular matrix protein 1 promotes follicular helper T cell differentiation and antibody production,Proc Natl Acad Sci USA2018 Aug 6
Lin Zhang, Qin Huang, Jiatao Lou, Liangjian Zou, Yiguo Wang, Peng Zhang,Guang Yang,Junyi Zhang, Lan Yu, Dai Yan, Chenyi Zhang, Jing Qiao, Shuting Wang, Sai Wang, Yongdong Xu, Hongbin Ji,Zhengjun Chen, Zhe Zhang,A novel PHD-finger protein 14/KIF4A complex overexpressed in lung cancer is involved in？cell？mitosis regulation？and？tumorigenesis.,Oncotarget2017,8:19684-98
Xiaoyu Merlin Zhang,Keliang Wu,Yuxuan Zheng,Han Zhao,Junpeng Gao,Zhenzhen Hou,Meiling Zhang,Jiaoyang Liao,Jingye Zhang,Yuan Gao,Yuanyuan Li,Lin Li, Fuchou Tang,Zijiang Chen,Jinsong Li,In vitro expansion of human sperm through nuclear transfer,Cell Res2019 Dec 19
Qiaoshi Lian, Jun Xu, Shanshan Yan, Min Huang, Honghua Ding, Xiaoyu Sun, Aiwei Bi, Jian Ding, Bing Sun, Meiyu Geng,Chemotherapy-induced intestinal inflammatory responses are mediated by exosome secretion of double-strand DNA via AIM2 inflammasome activation,Cell Res2017,27:784-800
Xiaoman Wang.Yiyue Zhao.Jian Zhang.Yong Chen.,Structural basis for DAXX interaction with ATRX,Protein？Cell
Hui Yang and Hong-Yu Hu*,Sequestration of cellular interacting partners by protein aggregates: implication in a loss-of-function pathology.,FEBS J283(20):3705-3717
Jing Fan,Ke Wang,Xian Du,Jianshu Wang,Suli Chen,Yimin Wang,Min Shi,Li Zhang,Xudong Wu,Dinghai Zheng,Changshou Wang,Lantian Wang,Bin Tian,Guohui Li,Yu Zhou,Hong Cheng,ALYREF links 3'-end processing to nuclear export of non-polyadenylated mRNAs,EMBO J2019 Mar 11

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