Representative Publications----Institute of Biochemistry and Cell Biology, Shanghai Institute for Biological Sciences, CAS

Research

Kun Zhang, Ping Wan, Liren Wang, Zhen Wang, Fangzhi Tan, Jie Li, Xiaolong Ma, Jin Cen, Xiang Yuan, Yang Liu, Zhen Sun, Xi Cheng, Yuanhua Liu, Xuhao Liu, Jiazhi Hu, Guisheng Zhong, Dali Li, Qiang Xia, Lijian Hui,Efficient expansion and CRISPR-Cas9-mediated gene correction of patient-derived hepatocytes for treatment of inherited liver diseases,Cell Stem Cell.20 May 2024.
Zijian Wang, Peng Tao, Luonan Chen,Brain-inspired chaotic spiking backpropagation,Natl Sci Rev.2024 Jan 30.
Hui Yang, Dinshaw J Patel,Structures, mechanisms and applications of RNA-centric CRISPR-Cas13,Nat Chem Biol.2024 May 3.
Lei Lu, Meizhu Bai, Yufang Zheng, Xiukun Wang, Zhongzhong Chen, Rui Peng, Richard H Finnell, Tongjin Zhao, Chengtao Li, Bo Wu, Yunping Lei, Jinsong Li, Hongyan Wang,The interaction of endorepellin and neurexin triggers neuroepithelial autophagy and maintains neural tube development,Sci Bull (Beijing).2024 Mar 15.
Jiaying Wu, Tuo Li, Meng Guo, Junsong Ji, Xiaoxi Meng, Tianlong Fu, Tengfei Nie, Tongkun Wei, Ying Zhou, Weihua Dong, Ming Zhang, Yongquan Shi, Xin Cheng, Hao Yin & Clinical Group,Treating a type 2 diabetic patient with impaired pancreatic islet function by personalized endoderm stem cell-derived islet tissue,Cell Discov.2024 Apr 30.
Si-Kun Guo, Chu-Xiao Liu, Yi-Feng Xu, Xiao Wang, Fang Nan, Youkui Huang, Siqi Li, Shan Nan, Ling Li, Edo Kon, Chen Li, Meng-Yuan Wei, Rina Su, Jia Wei, Shiguang Peng, Nitay Ad-El, Jiaquan Liu, Dan Peer, Ting Chen, Li Yang & Ling-Ling Chen,Therapeutic application of circular RNA aptamers in a mouse model of psoriasis,Nat Biotechnol.2024 Apr 23.
Jun Xiao, Shuang Wang, Longlong Chen, Xinyu Ding, Yuanhao Dang, Mingshun Han, Yuxiao Zheng, Huan Shen, Sifan Wu, Mingchang Wang, Dan Yang, Na Li, Chen Dong, Miao Hu, Chen Su, Weiyun Li, Lijian Hui, Youqiong Ye, Huiru Tang, Bin Wei, Hongyan Wang,25-Hydroxycholesterol regulates lysosome AMP kinase activation and metabolic reprogramming to educate immunosuppressive macrophages,Immunity.2024 Apr 12.
Baihua Wu, Xinyi Shentu, Haitao Nan, Pengcheng Guo, Shijie Hao, Jiangshan Xu, Shuncheng Shangguan, Lei Cui, Jin Cen, Qiuting Deng, Yan Wu, Chang Liu, Yumo Song, Xiumei Lin, Zhifeng Wang, Yue Yuan, Wen Ma, Ronghai Li, Yikang Li, Qiwei Qian, Wensi Du, Tingting Lai, Tao Yang, Chuanyu Liu, Xiong Ma, Ao Chen, Xun Xu, Yiwei Lai, Longqi Liu, Miguel A. Esteban & Lijian Hui,A spatiotemporal atlas of cholestatic injury and repair in mice,Nature Genetics.2024 Apr 16.
Chun-Rui Ma, Na Liu, Hong Li, Hong Xu, Xiao-Long Zhou,Activity reconstitution of Kre33 and Tan1 reveals a molecular ruler mechanism in eukaryotic tRNA acetylation,Nucleic Acids Res.2024 Apr 13.
Yining Qin, Fei-Long Meng,Taming AID mutator activity in somatic hypermutation,Trends Biochem Sci.2024 Apr 12.
Fei Li, Xudong Xing, Qiqi Jin, Xiang-Ming Wang, Pengfei Dai, Ming Han, Huili Shi, Ze Zhang, Xianlong Shao, Yunyi Peng, Yiqin Zhu, Jiayi Xu, Dan Li, Yu Chen, Wei Wu, Qiao Wang, Chen Yu, Luonan Chen, Fan Bai & Dong Gao,Sex differences orchestrated by androgens at single-cell resolution,Nature.2024 Apr 10.
Kuo Liu, Xinfeng Meng, Zixin Liu, Muxue Tang, Zan Lv, Xiuzhen Huang, Hengwei Jin, Ximeng Han, Xiuxiu Liu, Wenjuan Pu, Huan Zhu, Bin Zhou,Tracing the origin of alveolar stem cells in lung repair and regeneration,Cell.2024 Mar 27.
Yiming Liam Liu, Xinyu Thomas Tang, Hui Sophie Shu, Weiguo Zou, Bo O. Zhou,Fibrous periosteum repairs bone fracture and maintains the healed bone throughout mouse adulthood,Dev Cell.2024 Mar 27.
Zhangcheng Chen，Jing Yu，Huan Wang，Peiyu Xu，Luyu Fan，Fengxiu Sun，Sijie Huang，Pei Zhang，He Huang，Shuo Gu，Bowen Zhang，Yue Zhou，Xiaobo Wan，Gang Pei，H. Eric Xu，Jianjun Cheng，Sheng Wang,Flexible scaffold-based cheminformatics approach for polypharmacological drug design,Cell.2024 Mar 28.
Li Hou, Wei Liu, Hongdao Zhang, Ronghong Li, Miao Liu, Huijuan Shi & Ligang Wu,Divergent composition and transposon-silencing activity of small RNAs in mammalian oocytes,Genome Biol.2024 Mar 26.
Rong Gao, Peiluan Li, Yueqiong Ni, Xueqing Peng, Jing Ren, Luonan Chen,mNFE: microbiome network flow entropy for detecting pre-disease states of type 1 diabetes,Gut Microbes.2024 Mar 21.
Huan Wei, Jie Gao, Di-Hang Lin, Ruirong Geng, Jiaoyang Liao, Tian-Yu Huang, Guanyi Shang, Jiongjie Jing, Zong-Wei Fan, Duo Pan, Zi-Qi Yin, Tianming Li, Xinyu Liu, Shuang Zhao, Chen Chen, Jinsong Li, Xin Wang, Deqiang Ding & Mo-Fang Liu,piRNA loading triggers MIWI translocation from the intermitochondrial cement to chromatoid body during mouse spermatogenesis,Nat Commun.2024 Mar 15.
Chunchun Yuan, Xiang-Tian Yu, Jing Wang, Bing Shu, Xiao-Yun Wang, Chen Huang, Xia Lv, Qian-Qian Peng, Wen-Hao Qi, Jing Zhang, Yan Zheng, Si-Jia Wang, Qian-Qian Liang, Qi Shi, Ting Li, He Huang, Zhen-Dong Mei, Hai-Tao Zhang, Hong-Bin Xu, Jiarui Cui, Hongyu Wang, Hong Zhang, Bin-Hao Shi, Pan Sun, Hui Zhang, Zhao-Long Ma, Yuan Feng, Luonan Chen, Tao Zeng, De-Zhi Tang & Yong-Jun Wang,Multi-modal molecular determinants of clinically relevant osteoporosis subtypes,Cell Discov.2024 Mar 12.
Xiang Yuan, Jingqi Wu, Zhen Sun, Jin Cen, Yajing Shu, Chenhua Wang, Hong Li, Dongni Lin, Kun Zhang, Baihua Wu, Anil Dhawan, Ludi Zhang, Lijian Hui,Preclinical efficacy and safety of encapsulated proliferating human hepatocyte organoids in treating liver failure,Cell Stem Cell.2024 Mar 7.
Jing-Jing Li, Jingkun Liu, Yunqian Evelyn Li, Lin Veronica Chen, Hui Cheng, Yueying Li, Tao Cheng, Qian-Fei Wang, Bo O Zhou,Differentiation route determines the functional outputs of adult megakaryopoiesis,Immunity.2024 Mar 5.

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