Representative Publications----Institute of Biochemistry and Cell Biology, Shanghai Institute for Biological Sciences, CAS

Research

Chunman Zuo, Junjie Xia & Luonan Chen,Dissecting tumor microenvironment from spatially resolved transcriptomics data by heterogeneous graph learning,Nat Commun.2024 Jun 13.
Zi-Han Li, Xiao-Long Zhou,Eukaryotic AlaX provides multiple checkpoints for quality and quantity of aminoacyl-tRNAs in translation,Nucleic Acids Res.2024 Jun 13.
Yuting Chen, Chenchen Guo, Xinlei Cai, Liang Hu, Xinyuan Tong, Yun Xue, Qiqi Zhao, Tengfei Zhang, Yuan Chen, Yongting Fang, Yayi He, Yan Li, Bin Zhou & Hongbin Ji,Genetic tracing uncovers the importance of epithelial-to-mesenchymal transition in small cell lung cancer chemotherapy resistance but not metastasis,Cell Discov.2024 Jun 4.
Shi-Meng Cao, Hao Wu, Guo-Hua Yuan Yu-Hang Pan, Jun Zhang, Yu-Xin Liu, Siqi Li, Yi-Feng Xu, Meng-Yuan Wei, Li Yang, Ling-Ling Chen,Altered nucleocytoplasmic export of adenosine-rich circRNAs by PABPC1 contributes to neuronal function,Molecular Cell.2024 Jun 4.
Yun Xue, Yuting Chen, Sijia Sun, Xinyuan Tong, Yujia Chen, Shijie Tang, Xue Wang, Simin Bi, Yuqin Qiu, Qiqi Zhao, Zhen Qin, Qin Xu, Yingjie Ai, Leilei Chen, Beizhen Zhang, Zhijie Liu, Minbiao Ji, Meidong Lang, Luonan Chen, Guoliang Xu, Liang Hu , Dan Ye, Hongbin Ji,TET2-STAT3-CXCL5 nexus promotes neutrophil lipid transfer to fuel lung adeno-to-squamous transition,J Exp Med.2024 May 28.
Chaoliang Li, Panrui Zhang, Yadong Xie, Shishan Wang, Meng Guo, Xiaowei Wei, Kaiguang Zhang, Dan Cao, Rongbin Zhou, Sheng Wang, Xinyang Song, Shu Zhu, Wen Pan,Enterococcus-derived tyramine hijacks α2A-adrenergic receptor in intestinal stem cells to exacerbate colitis,Cell Host Microbe.2024 May 21.
Anxiang Cai, Yiwei Meng, Hang Zhou, Hong Cai, Xinghua Shao, Qin Wang, Yao Xu, Yin Zhou, Wenyan Zhou, Luonan Chen, Shan Mou,Podocyte Pathogenic Bone Morphogenetic Protein-2 Pathway and Immune Cell Behaviors in Primary Membranous Nephropathy,Adv Sci (Weinh).2024 May 24.
Wenqi Sun, Qianhua Dong, Xueqing Li, Jinxin Gao, Xianwen Ye, Chunyi Hu, Fei Li & Yong Chen,The SUN-family protein Sad1 mediates heterochromatin spatial organization through interaction with histone H2A-H2B,Nat Commun.2024 May 21.
Kun Zhang, Ping Wan, Liren Wang, Zhen Wang, Fangzhi Tan, Jie Li, Xiaolong Ma, Jin Cen, Xiang Yuan, Yang Liu, Zhen Sun, Xi Cheng, Yuanhua Liu, Xuhao Liu, Jiazhi Hu, Guisheng Zhong, Dali Li, Qiang Xia, Lijian Hui,Efficient expansion and CRISPR-Cas9-mediated gene correction of patient-derived hepatocytes for treatment of inherited liver diseases,Cell Stem Cell.20 May 2024.
Zijian Wang, Peng Tao, Luonan Chen,Brain-inspired chaotic spiking backpropagation,Natl Sci Rev.2024 Jan 30.
Hui Yang, Dinshaw J Patel,Structures, mechanisms and applications of RNA-centric CRISPR-Cas13,Nat Chem Biol.2024 May 3.
Lei Lu, Meizhu Bai, Yufang Zheng, Xiukun Wang, Zhongzhong Chen, Rui Peng, Richard H Finnell, Tongjin Zhao, Chengtao Li, Bo Wu, Yunping Lei, Jinsong Li, Hongyan Wang,The interaction of endorepellin and neurexin triggers neuroepithelial autophagy and maintains neural tube development,Sci Bull (Beijing).2024 Mar 15.
Jiaying Wu, Tuo Li, Meng Guo, Junsong Ji, Xiaoxi Meng, Tianlong Fu, Tengfei Nie, Tongkun Wei, Ying Zhou, Weihua Dong, Ming Zhang, Yongquan Shi, Xin Cheng, Hao Yin & Clinical Group,Treating a type 2 diabetic patient with impaired pancreatic islet function by personalized endoderm stem cell-derived islet tissue,Cell Discov.2024 Apr 30.
Si-Kun Guo, Chu-Xiao Liu, Yi-Feng Xu, Xiao Wang, Fang Nan, Youkui Huang, Siqi Li, Shan Nan, Ling Li, Edo Kon, Chen Li, Meng-Yuan Wei, Rina Su, Jia Wei, Shiguang Peng, Nitay Ad-El, Jiaquan Liu, Dan Peer, Ting Chen, Li Yang & Ling-Ling Chen,Therapeutic application of circular RNA aptamers in a mouse model of psoriasis,Nat Biotechnol.2024 Apr 23.
Jun Xiao, Shuang Wang, Longlong Chen, Xinyu Ding, Yuanhao Dang, Mingshun Han, Yuxiao Zheng, Huan Shen, Sifan Wu, Mingchang Wang, Dan Yang, Na Li, Chen Dong, Miao Hu, Chen Su, Weiyun Li, Lijian Hui, Youqiong Ye, Huiru Tang, Bin Wei, Hongyan Wang,25-Hydroxycholesterol regulates lysosome AMP kinase activation and metabolic reprogramming to educate immunosuppressive macrophages,Immunity.2024 Apr 12.
Baihua Wu, Xinyi Shentu, Haitao Nan, Pengcheng Guo, Shijie Hao, Jiangshan Xu, Shuncheng Shangguan, Lei Cui, Jin Cen, Qiuting Deng, Yan Wu, Chang Liu, Yumo Song, Xiumei Lin, Zhifeng Wang, Yue Yuan, Wen Ma, Ronghai Li, Yikang Li, Qiwei Qian, Wensi Du, Tingting Lai, Tao Yang, Chuanyu Liu, Xiong Ma, Ao Chen, Xun Xu, Yiwei Lai, Longqi Liu, Miguel A. Esteban & Lijian Hui,A spatiotemporal atlas of cholestatic injury and repair in mice,Nature Genetics.2024 Apr 16.
Chun-Rui Ma, Na Liu, Hong Li, Hong Xu, Xiao-Long Zhou,Activity reconstitution of Kre33 and Tan1 reveals a molecular ruler mechanism in eukaryotic tRNA acetylation,Nucleic Acids Res.2024 Apr 13.
Yining Qin, Fei-Long Meng,Taming AID mutator activity in somatic hypermutation,Trends Biochem Sci.2024 Apr 12.
Fei Li, Xudong Xing, Qiqi Jin, Xiang-Ming Wang, Pengfei Dai, Ming Han, Huili Shi, Ze Zhang, Xianlong Shao, Yunyi Peng, Yiqin Zhu, Jiayi Xu, Dan Li, Yu Chen, Wei Wu, Qiao Wang, Chen Yu, Luonan Chen, Fan Bai & Dong Gao,Sex differences orchestrated by androgens at single-cell resolution,Nature.2024 Apr 10.
Kuo Liu, Xinfeng Meng, Zixin Liu, Muxue Tang, Zan Lv, Xiuzhen Huang, Hengwei Jin, Ximeng Han, Xiuxiu Liu, Wenjuan Pu, Huan Zhu, Bin Zhou,Tracing the origin of alveolar stem cells in lung repair and regeneration,Cell.2024 Mar 27.

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