Representative Publications----Institute of Biochemistry and Cell Biology, Shanghai Institute for Biological Sciences, CAS

Research

Dongmei Cao, Pei Zhang, Sheng Wang,Advances in structure-based drug design: The potential for precision therapeutics in psychiatric disorders,Neuron.2024 Jan 23.
Zhen Qin, Meiting Yue, Shijie Tang, Fengying Wu, Honghua Sun, Yuan Li, Yongchang Zhang, Hiroki Izumi, Hsinyi Huang, Wanying Wang, Yun Xue, Xinyuan Tong, Shunta Mori, Tetsuro Taki, Koichi Goto, Yujuan Jin, Fei Li, Fu-Ming Li, Yijun Gao, Zhaoyuan Fang, Yisheng Fang, Liang Hu, Xiumin Yan, Guoliang Xu, Haiquan Chen, Susumu S Kobayashi, Andrea Ventura, Kwok-Kin Wong, Xueliang Zhu, Liang Chen, Shengxiang Ren, Luo-Nan Chen, Hongbin Ji,EML4-ALK fusions drive lung adeno-to-squamous transition through JAK-STAT activation,J Exp Med.2024 January 29.
Chuanjia Gu, Xue Wang, Kaiyu Wang, Fangfang Xie, Luonan Chen, Hongbin Ji, Jiayuan Sun,Cryoablation triggers type I interferon-dependent antitumor immunity and potentiates immunotherapy efficacy in lung cancer,J Immunother Cancer.2024 Jan 25.
Yanjing Zhu, Shijie Tang, Qiuyue Yuan, Jing Fu, Juan He, Zhuang Liu, Xiaofang Zhao, Yunguang Li, Yan Zhao, Yani Zhang, Xiaoyu Zhang, Yangqianwen Zhang, Yiqin Zhu, Wenwen Wang, Bo Zheng, Rui Wu, Tong Wu, Shuai Yang, Xinyao Qiu, Siyun Shen, Ji Hu, Luonan Chen, Yong Wang, Hongyang Wang, Dong Gao, Lei Chen,Integrated characterization of hepatobiliary tumor organoids provides a potential landscape of pharmacogenomic interactions,Cell Rep Med.2024 Jan 17.
Min Emma Huang, Yining Qin, Yafang Shang, Qian Hao, Chuanzong Zhan, Chaoyang Lian, Simin Luo, Liu Daisy Liu, Senxin Zhang, Yu Zhang, Yang Wo, Niu Li, Shuheng Wu, Tuantuan Gui, Binbin Wang, Yifeng Luo, Yanni Cai, Xiaojing Liu, Ziye Xu, Pengfei Dai, Simiao Li, Liang Zhang, Junchao Dong, Jian Wang, Xiaoqi Zheng, Yingjie Xu, Yihua Sun, Wei Wu, Leng-Siew Yeap & Fei-Long Meng,C-to-G editing generates double-strand breaks causing deletion, transversion and translocation,Nat Cell Biol.2024 Jan 23.
Zengxin Jiang, Guobin Qi, Xuecheng He, Yifan Yu, Yuting Cao, Changqing Zhang, Weiguo Zou, Hengfeng Yuan,Ferroptosis in Osteocytes as a Target for Protection Against Postmenopausal Osteoporosis,Adv Sci (Weinh).2024 Jan 17.
Yong Zhang, Jing-Bo Zhou, Yue Yin, En-Duo Wang, Xiao-Long Zhou,Multifaceted roles of t6A biogenesis in efficiency and fidelity of mitochondrial gene expression,Nucleic Acids Res.2024 Jan 16.
Xueming Meng, Cong Xu, Jiawei Li, Benhua Qiu, Jiajun Luo, Qin Hong, Yujie Tong, Chuyu Fang, Yanyan Feng, Rui Ma, Xiangyi Shi, Cheng Lin, Chen Pan, Xueliang Zhu, Xiumin Yan & Yao Cong,Multi-scale structures of the mammalian radial spoke and divergence of axonemal complexes in ependymal cilia,Nat Commun.2024 Jan 8.
Yadong Fu, Xiaoxi Zhou, Lin Wang, Weiguo Fan, Siqi Gao, Danyan Zhang, Zhiyang Ling, Yaguang Zhang, Liyan Ma, Fang Bai, Jiamei Chen, Bing Sun, Ping Liu,Salvianolic acid B attenuates liver fibrosis by targeting Ecm1 and inhibiting hepatocyte ferroptosis,Redox Biol.2024 Jan 3.
Qian Liu, Jing Zhang, Chenchen Guo, Mengcheng Wang, Chenfei Wang, Yilv Yan, Liangdong Sun, Di Wang, Lele Zhang, Huansha Yu, Likun Hou, Chunyan Wu, Yuming Zhu, Gening Jiang, Hongwen Zhu, Yanting Zhou, Shanhua Fang, Tengfei Zhang, Liang Hu, Junqiang Li, Yansheng Liu, Hui Zhang, Bing Zhang, Li Ding, Ana I Robles, Henry Rodriguez, Daming Gao, Hongbin Ji, Hu Zhou, Peng Zhang,Proteogenomic characterization of small cell lung cancer identifies biological insights and subtype-specific therapeutic strategies,Cell.2024 Jan 4.
Xiao-Jie Zhang, Bin-Bin Han, Zhen-Yu Shao, Rui Yan, Juan Gao, Ting Liu, Zi-Yang Jin, Weiyi Lai, Zhi-Mei Xu, Chao-Han Wang, Fengjuan Zhang, Chan Gu, Yin Wang, Hailin Wang, Colum P. Walsh, Fan Guo, Guo-Liang Xu & Ya-Rui Du,Auto-suppression of Tet dioxygenases protects the mouse oocyte genome from oxidative demethylation,Nat Struct Mol Biol.2024 Jan 4.
Yibing Bai, Tongzhou Li, Qinshu Wang, Weiqiang You, Haochen Yang, Xintian Xu, Ziyi Li, Yu Zhang, Chengsong Yan, Lei Yang, Jiaqian Qiu, Yuanhua Liu, Shiyang Chen, Dongfang Wang, Binlu Huang, Kexin Liu, Bao- Liang Song, Zhuozhong Wang, Kang Li, Xin Liu, Guangchuan Wang, Weiwei Yang, Jianfeng Chen, Pei Hao, Zemin Zhang, Zhigang Wang, Zheng-Jiang Zhu, Chenqi Xu,Shaping immune landscape of colorectal cancer by cholesterol metabolites,EMBO Mol Med.2024 Jan 2.
Jing Cao, Qi Jason Yao, Jiao Wu, Xiaonan Chen, Lin Huang, Wanshan Liu, Kun Qian, Jing-Jing Wan, Bo O Zhou,Deciphering the metabolic heterogeneity of hematopoietic stem cells with single-cell resolution,Cell Metab.2024 Jan 2,
Jingjing Hong, Tingting Li, Yulin Chao, Yidan Xu, Zhini Zhu, Zixuan Zhou, Weijie Gu, Qianhui Qu & Dianfan Li,Molecular basis of the inositol deacylase PGAP1 involved in quality control of GPI-AP biogenesis,Nat Commun.2024 Jan 2.
Yuwei Wang, Pei Zhang, Yulin Chao, Zhini Zhu, Chuanhui Yang, Zixuan Zhou, Yaohui Li, Yonghui Long, Yuehua Liu, Dianfan Li, Sheng Wang & Qianhui Qu,Transport and inhibition mechanism for VMAT2-mediated synaptic vesicle loading of monoamines,Cell Res.2024 Jan 2.
Yujuan Jin, Qiqi Zhao, Weikang Zhu, Yan Feng, Tian Xiao, Peng Zhang, Liyan Jiang, Yingyong Hou, Chenchen Guo, Hsinyi Huang, Yabin Chen, Xinyuan Tong, Jiayu Cao, Fei Li, Xueliang Zhu, Jun Qin, Dong Gao, Xin-Yuan Liu, Hua Zhang, Luonan Chen, Roman K Thomas, Kwok-Kin Wong, Lei Zhang, Yong Wang, Liang Hu, Hongbin Ji,Correction to: Identification of TAZ as the essential molecular switch in orchestrating SCLC phenotypic transition and metastasis,Natl Sci Rev.2023 Dec 28.
Chunye Liu, Yishu Xu, Guowei Yang, Yu Tao, Jiali Chang, Shihui Wang, Tom H. Cheung, Jianfeng Chen, Yi Arial Zeng,Niche inflammatory signals control oscillating mammary regeneration and protect stem cells from cytotoxic stress,Cell Stem Cell.2023 Dec 13.
Xuebin Zhang, Zengming Wang, Shengsong Huang, Dongyin He, Weiwei Yan, Qian Zhuang, Zixian Wang, Chenyang Wang, Qilong Tan, Ziqun Liu, Tao Yang, Ying Liu, Ruobing Ren, Jing Li, William Butler, Huiru Tang, Gong-Hong Wei, Xin Li, Denglong Wu, and Zhenfei Li,Active DHEA uptake in the prostate gland correlates with aggressive prostate cancer,J Clin Invest.2023 Dec 15.
Xiangpeng Sheng, Fang Zhu, Hong Peng, Fan Yang, Yi Yang, Cong Yang, Zhen Wang, Wei Chen, Deyin Guo & Ronggui Hu,Host cyclophilin A facilitates SARS-CoV-2 infection by binding and stabilizing spike on virions,Signal Transduct Target Ther.2023 Dec 14.
Yi Li, Zixin Liu, Ximeng Han, Feng Liang, Qianyu Zhang, Xiuzhen Huang, Xin Shi, Huanhuan Huo, Maoying Han, Xiuxiu Liu, Huan Zhu, Lingjuan He, Linghong Shen, Xinyang Hu, Jian’an Wang, Qing-Dong Wang, Nicola Smart, Bin Zhou and Ben He,Dynamics of Endothelial Cell Generation and Turnover in Arteries During Homeostasis and Diseases,Circulation.2023 Dec 12.

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