Representative Publications----Institute of Biochemistry and Cell Biology, Shanghai Institute for Biological Sciences, CAS

Research

Xing He,Chenqi Xu,Immune checkpoint signaling and cancer immunotherapy,Cell Res2020 May 28.
Jiashu Tang, Qingrun Li, Jiaming Li, Jiarui Wu,Rong Zeng,Systematic Synergy of Glucose and GLP-1 to Stimulate Insulin Secretion Revealed by Quantitative Phosphoproteomics,Sci Rep.2017,7:1018
in Xiao-Fei, Wu Shuai,Yang Yuan-Qin, Fang Xian-Long, Xu Hai-Neng, Liu Xin-Yuan, Zheng Shu, Zhang Kang-Jian,c-MYC-Regulated miRNA-92b Inhibits Expression of The E3 Ligase FBXW7 in Colorectal Cancer,Progress in Biochemistry and Biophysics43(7):673-683
Yunxiang Zang, Mingliang Jin, Huping Wang, Zhicheng Cui, Liangliang Kong, Caixuan Liu & Yao Cong,Staggered ATP binding mechanism of eukaryotic chaperonin TRiC (CCT) revealed through high-resolution cryo-EM,Nature Structural & Molecular Biology23，1083-1091
Xiao-Long Zhou, Yun Chen, Zhi-Peng Fang, Zhi-Rong Ruan, Yong Wang, Ru-Juan Liu, Mei-Qin Xue,and En-Duo Wang,Translational quality control by bacterial threonyl-tRNA synthetases,J. Biol. Chem.291（40）, 21208 –21221
Yu-Hang Xing, Zhiqiang Bai, Chu-Xiao Liu, Shi-Bin Hu, Meihua Ruan, Ling-Ling Chen,Research progress of long noncoding RNA in China,IUBMB Life68:887–893
Chao Peng,Catherine CL Wong,The story of protein arginine methylation: characterization, regulation,？and？function.,Expert Rev. Proteomics2017,14:157-170
Jun Chen, Shengbao Suo, Patrick. P.L. Tam, Jing-Dong J. Han, Guangdun Peng*, Naihe Jing*.,Using Geo-seq to undertake Low-input RNA-sequencing analysis of cell samples at defined geographical locations to enable mapping of the in situ position of single cells,Nature Protocol1
Lunyi Li,Xingdong Guo,Xiaoshan Shi,Changting Li,Wei Wu,Chengsong Yan,Haopeng Wang,Hua Li, Chenqi Xu.,Ionic CD3？Lck interaction regulates the initiation of T-cell receptor signaling.,Proc Natl Acad Sci U S A2017,E5891-E5899
Wangxin Guo,Lin Li,Juan He,Zhuang Liu,Ming Han,Fei Li,Xinyi Xia,Xiaoyu Zhang,Yao Zhu,Yu Wei,Yunguang Li,Rebiguli Aji,Hao Dai,Hui Wei,Chunfeng Li,Yu Chen,Luonan Chen,Dong Gao,Single-cell transcriptomics identifies a distinct luminal progenitor cell type in distal prostate invagination tips,Nat Genet2020 Aug 17.
Qibiao Wu,Yahui Tian,Jian Zhang,Xinyuan Tong,Hsinyi Huang,Shuai Li,Hong Zhao,Ying Tang,Chongze Yuan,Kun Wang,Zhaoyuan Fang,Lei Gao,Xin Hu,Fuming Li,Zhen Qin,Shun Yao,Ting Chen,Haiquan Chen,Gong Zhang,Wanting Liu,Yihua Sun,Luonan Chen,Kwok-Kin Wong,Kai Ge,Liang Chen,Hongbin Ji,In vivo CRISPR screening unveils histone demethylase UTX as an important epigenetic regulator in lung tumorigenesis,Proc Natl Acad Sci USA2018 Apr 9
Rui Liu, Pei Chen, Kazuyuki Aihara, Luonan Chen.,Identifying early-warning signals of critical transitions with strong noise by dynamical network markers.,Scientific Reports
Peng Zhang, Shuting Wang, Sai Wang, Jing Qiao, Lei Zhang, Zhe Zhang, Zhengjun Chen,Dual function of partitioning-defective 3 in the regulation of YAP phosphorylation and activation,Cell Discovery
Xuemei Chen,Shuai Wang,Ying Zhou,Yanfei Han,Shengtian Li,Qing Xu,Longyong Xu,Ziqi Zhu,Youming Deng,Lu Yu,Lulu Song,Adele Pin Chen,Juan Song,Eiki Takahashi,Guang He,Lin He,Weidong Li,Charlie Degui Chen,Phf8 histone demethylase deficiency causes cognitive impairments through the mTOR pathway,Nat Commun2018,9:114
Juanjuan Long, Chenhui Huang, Yanyan Chen, Ying Zhang, Shaohua Shi, Ligang Wu, Yie Liu, Chengyu Liu, Jian Wu,Ming Lei,Telomeric TERB1–TRF1 interaction is crucial for male meiosis,Nat Struct Mol Biol2017,24:1073-1080
Liu YJ, Liu C, Chang Z, Wadas B, Brower CS, Song ZH, Xu ZL, Shang YL2, Liu WX, Wang LN, Dong W, Varshavsky A, Hu RG, Li W.,Degradation of the Separase-cleaved Rec8, a Meiotic Cohesin Subunit, by the N-end Rule Pathway.,J Biol Chem.291:7426-38
Lingfei Zhang,Shuai Jiang,Mofang Liu,MicroRNA regulation and analytical methods in cancer cell metabolism,Cell？Mol Life Sci2017,74(16):2929-2941
Zhu J, Shang Y, Zhang M,Mechanistic basis of MAGUK-organized complexes in synaptic development and signalling,Nat Rev Neurosci.
Jiankun Lyu,Sheng Wang,Trent E.Balius,Isha Singh,Anat Levit,Yurii S.Moroz,Matthew J’Meara,Tao Che,Enkhjargal Algaa,Kateryna Tolmachova,Andrey A.Tolmachev,Brian K.Shoichet,Bryan L.Roth,John J.Irwin.,Ultra-large library docking for discovering new chemotypes,Nature2019,566:224-229
Xianfa Yang,Boqiang Hu,Yu Hou,Yunbo Qiao,Ran Wang,Yingying Chen,Yun Qian,Su Feng,Jun Chen,Chang Liu,Guangdun Peng,Fuchou Tang,Naihe Jing,Silencing of developmental genes by H3K27me3 and DNA methylation reflects the discrepant plasticity of embryonic and extraembryonic lineages,Cell Res2018 Feb 20

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