Representative Publications----Institute of Biochemistry and Cell Biology, Shanghai Institute for Biological Sciences, CAS

Research

Chenchen Wang,Ying Tong,Yankai Wen,Jie Cai,Han Guo,Lifeng Huang,Min Xu,Mingxuan Feng,Xiaosong Chen,Jianjun Zhang,Hailong Wu,Xiaoni Kong,Qiang Xia,Hepatocellular Carcinoma-associated Protein TD26 Interacts and Enhances SREBP1 Activity to Promote Tumor Cell Proliferation and Growth,Hepatology2018 Apr 16
Xing He,Chenqi Xu,PD-1: A Driver or Passenger of T Cell Exhaustion?,Mol Cell2020 Mar 5.
Sujing Yuan, Xianlong Fang, Yanni Xu, Aimin Ni, Xin-Yuan Liu, Liang Chu,An oncolytic adenovirus that expresses the HAb18 and interleukin 24 genes exhibits enhanced antitumor activity in hepatocellular carcinoma cells,Oncotarget[Epub ahead of print]
Lianxin Hu, Jiajun Xu, Meng-Xin Yin, Liguo Zhang, Yi Lu, Wenqing Wu, Zhaoyu Xu, Margaret S. Ho, Guanjun Gao, Yun Zhao, Lei Zhang,Ack promotes tissue growth via phosphorylation and suppression of the Hippo pathway component Expanded.,Cell Discovery2016, 2, 15047
Jianhuang Xue,Guodong Chen,Fuhua Hao,Hui Chen,Zhaoyuan Fang,Fangfang Chen,Bo Pang,Qinglin Yang,Xinben Wei,Qiangqiang Fan,Changpeng Xin,Jiaohong Zhao,Xuan Deng,Bangan Wang,Xiaojie Zhang,Yueying Chu,Hui Tang,Huiyong Yin,Weimin Ma,Luonan Chen,Jianping Ding,Elmar Weinhold,Rahul M.Kohli,Wen Liu,Zhengjiang Zhu,Kaiyao Huang,Huiru Tang,Guoliang Xu,A vitamin-C-derived DNA modification catalysed by an algal TET homologue,Nature2019 May 1
Weiguo Fan,Tianhui Liu,Wen Chen,Seddik Hammad,Thomas Longerich,Yadong Fu,Nan Li,Yajing He,Cui Liu,Yaguang Zhang,Qiaoshi Lian,Xinhao Zhao,Chenghua Yan,Li Li,Chunyan Yi,Zhiyang Ling,Liyan Ma,Xinyan Zhao,Hufeng Xu,Ping Wang,Min Cong,Hong You,Zhihong Liu,Yan Wang,Jianfeng Chen,Dangsheng Li,Lijian Hui,Steven Dooley,Jinlin Hou,Jidong Jia,Bing Sun,ECM1 Prevents Activation of Transforming Growth Factor beta, Hepatic Stellate Cells, and Fibrogenesis in Mice,Gastroenterology2019 Jul 27
Daisong Wang, Chunye Liu, Jingqiang Wang, Yingying Jia, Xin Hu, Hai Jiang, Zhiming Shao,Yi Arial Zeng.,Protein C Receptor stimulates multiple signaling pathways in breast cancer cells,J Biol Chem
Jiarui Wu,New ways to maintain or disrupt metabolic homeostasis.,J Mol Cell Biol.2017,9:351
Zhan Xu, Matthew B. Greenblatt, Guang Yan, Heng Feng, Jun Sun, Sutada Lotinun, Nicholas Brady,Roland Baron, Laurie H.Glimcher，Weiguo Zou.,SMURF2 regulates bone homeostasis by disrupting SMAD3 interaction with vitamin D receptor in osteoblasts./Nature Communications,Nat Commun2017,8:14570
Qinggang Dai, Zhan Xu, Xuhui Ma, Ningning Niu, Siru Zhou, Furong Xie, Lingyong Jiang, Jun Wang and Weiguo Zou,mTOR/Raptor signaling is critical for skeletogenesis in mice through the regulation of Runx2 expression,Cell Death Differ2017,11:1886-1899
Jifan Shi, Tiejun Li, and Luonan Chen.,Towards a critical transition theory under different temporal scales and noise strengths.,Physical Review E
Ortiz-Cuaran S, Scheffler M, Plenker D, Dahmen L, Scheel AH, Fernandez-Cuesta L, Meder L, Lovly CM, Persigehl T, Merkelbach-Bruse S, Bos M, Michels S, Fischer R, Albus K, K？nig K, Schildhaus HU, Fassunke J, Ihle MA, Pasternack H, Heydt C, Becker C, Altmüller J, Ji H, Müller C, Florin A, Heuckmann JM, Nuernberg P, Ansén S, Heukamp LC, Berg J, Pao W, Peifer M, Buettner R, Wolf J, Thomas RK, Sos ML.,Heterogeneous Mechanisms of Primary and Acquired Resistance to Third-Generation EGFR Inhibitors.,Clin Cancer Res.2016 Oct 1;22(19):4837-4847.
Kangjian Zhang, Xiaofei Yin, Yuanqin Yang, Huiling Li, Yanni Xu, Lieyang Chen, Xijun Liu, Sujing Yuan, Xianlong Fang, Jing Xiao, Shuai Wu, Haineng Xu, Liang Chu, Kanstantsin V. Katlinski, Yuliya V. Katlinskaya, Rongbing Guo, Guangwen Wei, Dacheng Wang, Xinyuan Liu,Serge Y.Fuchs.,A Potent In Vivo Antitumor Efficacy of Novel Recombinant Type I Interferon.,Clin Cancer Res.2017,23:2038-2049
Siqi Li,Xiang Li,Wei Xue,Lin Zhang,Shi-Meng Cao,Yunni Lei,LiangZhong Yang,Sikun Guo,Jialin Zhang,Xiang Gao,Jia Wei,Jinsong Li,LiYang,Lingling Chen,Screening for functional circular RNAs using the CRISPR-Cas13 system,Nat Methods2020 Dec 7.
Xiangtian Yu, Jingsong Zhang, Shaoyan Sun, Xin Zhou, Tao Zeng, Luonan Chen,Individual-specific edge-network analysis for disease prediction,Nucleic Acids Res2017,45, e170
Xiaoli Wang, Zhiqiang Ku, Xiang Zhang, Xiaohua Ye, Jinhuan Chen, Qingwei Liu, Wei Zhang, Chao Zhang, Zhenglin Fu, Xia Jin, Yao Cong, Zhong Huang.,Structure,Immunogenicity and Protective Mechanism of an Engineered Enterovirus 71-Like Particle Vaccine Mimicking 80S Empty Capsid.,J Virol.？
Jing Gao,Lingli He,Yan Shi,Mingjun Cai,Haijiao Xu,Junguang Jiang,Lei Zhang,Hongda Wang,Cell contact and pressure control of YAP localization and clustering revealed by superresolution imaging,Nanoscale
Yangyang Shao,Ning Lu,Zhenfang Wu,Chen Cai,Shanshan Wang,Lingli Zhang,Fan Zhou,Shijun Xiao,Lin Liu,Xiaofei Zeng,Huajun Zheng,Chen Yang,Zhihu Zhao,Guoping Zhao,Jinqiu Zhou,Xiaoli Xue,Zhongjun Qin,Creating a functional single-chromosome yeast,Nature2018 Aug 1
Bing Zhang,Jun Li,Xiaolin Yang,Lijie Wu,Jia Zhang,Yang Yang,Yao Zhao,Lu Zhang,Xiuna Yang,Xiaobao Yang, Xi Cheng,Zhijie Liu,Biao Jiang,Hualiang Jiang,Luke W.Guddat,Haitao Yang,Zihe Rao,Crystal Structures of Membrane Transporter MmpL3, an Anti-TB Drug Target,Cell2019,176:636-648
Tianlong Zhang,Marie-Pierre Péli-Gulli,Zhen Zhang,Xin Tang,Jie Ye,Claudio De Virgilio,Jianping Ding,Structural insights into the EGO-TC-mediated membrane tethering of the TORC1-regulatory Rag GTPases,Sci Adv2019 Sep 25

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