Representative Publications----Institute of Biochemistry and Cell Biology, Shanghai Institute for Biological Sciences, CAS

Research

Wangxin Guo,Lin Li,Juan He,Zhuang Liu,Ming Han,Fei Li,Xinyi Xia,Xiaoyu Zhang,Yao Zhu,Yu Wei,Yunguang Li,Rebiguli Aji,Hao Dai,Hui Wei,Chunfeng Li,Yu Chen,Luonan Chen,Dong Gao,Single-cell transcriptomics identifies a distinct luminal progenitor cell type in distal prostate invagination tips,Nat Genet2020 Aug 17.
Qibiao Wu,Yahui Tian,Jian Zhang,Xinyuan Tong,Hsinyi Huang,Shuai Li,Hong Zhao,Ying Tang,Chongze Yuan,Kun Wang,Zhaoyuan Fang,Lei Gao,Xin Hu,Fuming Li,Zhen Qin,Shun Yao,Ting Chen,Haiquan Chen,Gong Zhang,Wanting Liu,Yihua Sun,Luonan Chen,Kwok-Kin Wong,Kai Ge,Liang Chen,Hongbin Ji,In vivo CRISPR screening unveils histone demethylase UTX as an important epigenetic regulator in lung tumorigenesis,Proc Natl Acad Sci USA2018 Apr 9
Rui Liu, Pei Chen, Kazuyuki Aihara, Luonan Chen.,Identifying early-warning signals of critical transitions with strong noise by dynamical network markers.,Scientific Reports
Peng Zhang, Shuting Wang, Sai Wang, Jing Qiao, Lei Zhang, Zhe Zhang, Zhengjun Chen,Dual function of partitioning-defective 3 in the regulation of YAP phosphorylation and activation,Cell Discovery
Xuemei Chen,Shuai Wang,Ying Zhou,Yanfei Han,Shengtian Li,Qing Xu,Longyong Xu,Ziqi Zhu,Youming Deng,Lu Yu,Lulu Song,Adele Pin Chen,Juan Song,Eiki Takahashi,Guang He,Lin He,Weidong Li,Charlie Degui Chen,Phf8 histone demethylase deficiency causes cognitive impairments through the mTOR pathway,Nat Commun2018,9:114
Juanjuan Long, Chenhui Huang, Yanyan Chen, Ying Zhang, Shaohua Shi, Ligang Wu, Yie Liu, Chengyu Liu, Jian Wu,Ming Lei,Telomeric TERB1–TRF1 interaction is crucial for male meiosis,Nat Struct Mol Biol2017,24:1073-1080
Liu YJ, Liu C, Chang Z, Wadas B, Brower CS, Song ZH, Xu ZL, Shang YL2, Liu WX, Wang LN, Dong W, Varshavsky A, Hu RG, Li W.,Degradation of the Separase-cleaved Rec8, a Meiotic Cohesin Subunit, by the N-end Rule Pathway.,J Biol Chem.291:7426-38
Lingfei Zhang,Shuai Jiang,Mofang Liu,MicroRNA regulation and analytical methods in cancer cell metabolism,Cell？Mol Life Sci2017,74(16):2929-2941
Zhu J, Shang Y, Zhang M,Mechanistic basis of MAGUK-organized complexes in synaptic development and signalling,Nat Rev Neurosci.
Jiankun Lyu,Sheng Wang,Trent E.Balius,Isha Singh,Anat Levit,Yurii S.Moroz,Matthew J’Meara,Tao Che,Enkhjargal Algaa,Kateryna Tolmachova,Andrey A.Tolmachev,Brian K.Shoichet,Bryan L.Roth,John J.Irwin.,Ultra-large library docking for discovering new chemotypes,Nature2019,566:224-229
Xianfa Yang,Boqiang Hu,Yu Hou,Yunbo Qiao,Ran Wang,Yingying Chen,Yun Qian,Su Feng,Jun Chen,Chang Liu,Guangdun Peng,Fuchou Tang,Naihe Jing,Silencing of developmental genes by H3K27me3 and DNA methylation reflects the discrepant plasticity of embryonic and extraembryonic lineages,Cell Res2018 Feb 20
Yang Wang,Shibin Hu,Mengran Wang,Runwen Yao,Di Wu,Li Yang,Lingling Chen,Genome-wide screening of NEAT1 regulators reveals cross-regulation between paraspeckles and mitochondria,Nature Cell Biology2018 Sep 25
Shicheng Zhang,Linlin Wang,Ye Tao,Tuya Bai,Rong Lu,Tianlong Zhang,Jiangye Chen,Jianping Ding.,Structural basis for the functional role of the Shu complex in homologous recombination,Nucleic Acids Res2017,45:13068-13079
He Xu,Chunmei Yue,Ting Zhang,Yuanyuan Li,Ao Guo,Jiaoyang Liao,Gang Pei,Jinsong Li,Naihe Jing,Derivation of Haploid Neurons from Mouse Androgenetic Haploid Embryonic Stem Cells,Neurosci Bull2017,33:361-364
Shimin Wang, Yi Lu, Mengxin Yin, Chao Wang, Wei Wu, Jinhui Li, Wenqing Wu, Lianxin Hu, Yun Zhao and Lei Zhang,Importin α1 mediates Yorkie nuclear import via N-terminal non-canonical nuclear localization signal,Journal of Biological Chemistry291:7926-7937
Feng Wang, Xing Fu, Peng Chen, Ping Wu, Xiaojuan Fan, Na Li, Hong Zhu, Ting-Ting Jia, Hongbin Ji, Zefeng Wang, Catherine C L Wong, Ronggui Hu, Jingyi Hui.,SPSB1-mediated HnRNP A1 ubiquitylation regulates alternative splicing and cell migration in EGF signaling,Cell Res2017,27:540-558
Chenchen Wang,Ying Tong,Yankai Wen,Jie Cai,Han Guo,Lifeng Huang,Min Xu,Mingxuan Feng,Xiaosong Chen,Jianjun Zhang,Hailong Wu,Xiaoni Kong,Qiang Xia,Hepatocellular Carcinoma-associated Protein TD26 Interacts and Enhances SREBP1 Activity to Promote Tumor Cell Proliferation and Growth,Hepatology2018 Apr 16
Xing He,Chenqi Xu,PD-1: A Driver or Passenger of T Cell Exhaustion?,Mol Cell2020 Mar 5.
Sujing Yuan, Xianlong Fang, Yanni Xu, Aimin Ni, Xin-Yuan Liu, Liang Chu,An oncolytic adenovirus that expresses the HAb18 and interleukin 24 genes exhibits enhanced antitumor activity in hepatocellular carcinoma cells,Oncotarget[Epub ahead of print]
Lianxin Hu, Jiajun Xu, Meng-Xin Yin, Liguo Zhang, Yi Lu, Wenqing Wu, Zhaoyu Xu, Margaret S. Ho, Guanjun Gao, Yun Zhao, Lei Zhang,Ack promotes tissue growth via phosphorylation and suppression of the Hippo pathway component Expanded.,Cell Discovery2016, 2, 15047

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