Representative Publications----Institute of Biochemistry and Cell Biology, Shanghai Institute for Biological Sciences, CAS

Research

Lulu Zhang, Fang Du, Qiqi Jin, Li Sun, Boqian Wang, Ziyang Tan, Xinyu Meng, Baozhen Huang, Yifan Zhan, Wenqiong Su, Rui Song, Chunmei Wu, Luonan Chen, Xiaoxiang Chen, Xianting Ding,Identification and Characterization of CD8+CD27+CXCR3- T Cell Dysregulation and Progression-Associated Biomarkers in Systemic Lupus Erythematosus,Adv Sci2023 Oct 24.
Lin Shan, Pan Li, Hongtao Yu, Ling-Ling Chen,Emerging roles of nuclear bodies in genome spatial organization,Trends Cell Biol.2023 Nov 21.
Maoying Han,Zixin Liu,Lei Liu,Xiuzhen Huang,Haixiao Wang,Wenjuan Pu,Enci Wang,Xiuxiu Liu,Yan Li,Lingjuan He,Xufeng Li,Jiayu Wu,Lin Qiu,Ruling Shen,Qingdong Wang,Yong Ji,Reza Ardehali,Qiang Shu,Kathy O. Lui,Lixin Wang,Bin Zhou,Dual genetic tracing reveals a unique fibroblast subpopulation modulating cardiac fibrosis,Nat Genet2023 Mar 23.
Jiayin Peng,Fei Li,Jia Wang,Chaoxiong Wang,Yiao Jiang,Biao Liu,Juan He,Kai Yuan,Chenyu Pan,Moubin Lin,Bin Zhou,Luonan Chen,Dong Gao,Yun Zhao,Identification of a rare Gli1+ progenitor cell population contributing to liver regeneration during chronic injury,Cell Discov2022 Nov 1.
Hui Yang,Dinshaw J. Patel,A type III-E CRISPR Craspase exhibiting RNase and protease activities,Cell Res2022 Oct 24.
Lu Li,Lei Cui,Ping Lin,Zhaoyuan Liu,Shujie Bao, Xiaolong Ma,Haitao Nan,Wencheng Zhu,Jin Cen,Yunuo Mao,Xiong Ma,Lingyong Jiang,Yu Nie,Florent Ginhoux,Yixue Li,Hong Li,Lijian Hui,Kupffer-cell-derived IL-6 is repurposed for hepatocyte dedifferentiation via activating progenitor genes from injury-specific enhancers,2023 Feb 13.
Chunman Zuo,Yijian Zhang,Chen Cao,Jinwang Feng,Mingqi Jiao,Luonan Chen,Elucidating tumor heterogeneity from spatially resolved transcriptomics data by multi-view graph collaborative learning,Nat Commun2022 Oct 10.
Jian Chen,Shizhen Qiu,Wentao Li,Kun Wang,Yu Zhang,Han Yang,Baichuan Liu,Guangfei Li,Li Li,Min Chen,Junjie Lan,Jiahua Niu,Peijie He,Lei Cheng,Gaofeng Fan,Xin Liu,Xianmin Song,Chenqi Xu,Haitao Wu,Haopeng Wang,Tuning charge density of chimeric antigen receptor optimizes tonic signaling and CAR-T cell fitness,Cell Res2023 Mar 8.
Xin Wang,Yueqiu Tan,Mofang Liu,Defective piRNA Processing and Azoospermia,NEW ENGL J MED2022 Apr 28.
Guixin Peng,Xueling Mao,Yating Cao,Shiying Yao,Qingrun Li,Xin Chen,Enduo Wang,Xiaolong Zhou,RNA granule-clustered mitochondrial aminoacyl-tRNA synthetases form multiple complexes with the potential to fine-tune tRNA aminoacylation,Nucleic Acids Res2022 Dec 12.
Youkui Huang,Baoqing Gao,Quan Meng,Liangzhong Yang,Xukai Ma,Hao Wu,Yuhang Pan,Li Yang,Dong Li,Lingling Chen,CRISPR-dCas13-tracing reveals transcriptional memory and limited mRNA export in developing zebrafish embryos,Genome Biol2023 Jan 19.
Tingting Yu,Yi Zhang,Wenqiang Zheng,Siqi Wu,Guoqiang Li,Yong Zhang,Niu Li,Ruen Yao,Pengfei Fang,Jian Wang,Xiaolong Zhou,Selective degradation of tRNASer(AGY) is the primary driver for mitochondrial seryl-tRNA synthetase-related disease,Nucleic Acids Res2022 Nov 9.
Shijie Tang,Yun Xue,Zhen Qin, Zhaoyuan Fang,Yihua Sun,Chongzhe Yuan,Yunjian Pan,Yue Zhao,Xinyuan Tong,Jian Zhang,Hsinyi Huang,Yuting Chen,Liang Hu,Dasong Huang,Ruiqi Wang,Weiguo Zou,Yuan Li,Roman K Thomas,Andrea Ventura,Kwok-Kin Wong,Haiquan Chen,Luonan Chen,Hongbin Ji,Counteracting lineage-specific transcription factor network finely tunes lung adeno-to-squamous transdifferentiation through remodeling tumor immune microenvironment,Natl Sci Rev2023 Feb 14.
Guoqing Cai,Yijun Qi,Ping Wei,Hong Gao,Chenqi Xu,Yun Zhao,Xiujuan Qu,Feng Yao,Weiwei Yang,IGFBP1 Sustains Cell Survival during Spatially-Confined Migration and Promotes Tumor Metastasis,Adv Sci2023 Jun 9.
Huan Zhao,Xiuzhen Huang,Zixin Liu,Liang Lai,Ruilin Sun,Ruling Shen,Yan Li,Lingjuan He,Wenjuan Pu,Zan Lv,Yi Li,Ximeng Han,Xiuxiu Liu,Bin Zhou,Use of a dual genetic system to decipher exocrine cell fate conversions in the adult pancreas,Cell Discov2023 Jan 3.
Zhaoyuan Fang,Xiangkun Han,Yueqing Chen,Xinyuan Tong,Yun Xue,Shun Yao,Shijie Tang,Yunjian Pan,Yihua Sun,Xue Wang,Yujuan Jin,Haiquan Chen,Liang Hu,Lijian Hui,Lin Li,Luonan Chen,Hongbin Ji,Oxidative stress-triggered Wnt signaling perturbation characterizes the tipping point of lung adeno-to-squamous transdifferentiation,Signal Transduct Target Ther2023 Jan 13.
Xin Wang,Anne Ramat,Martine Simonelig,Mofang Liu,Emerging roles and functional mechanisms of PIWI-interacting RNAs,Nat Rev Mol Cell Biol2022 Sep 14.
Xiuxiu Liu,Wendong Weng,Lingjuan He,Bin Zhou,Genetic recording of in vivo cell proliferation by ProTracer,Nat Protoc2023 Jun 2.
Rui Zhang,Xianteng Hou,Changwan Wang,Jiaxin Li,Junyan Zhu,Yingbo Jiang,Fajian Hou,The Endoplasmic Reticulum ATP13A1 is Essential for MAVS-Mediated Antiviral Innate Immunity,Adv Sci2022 Oct 10.
Qian Wang,Yunlei Cao,Lijuan Shen,Taoran Xiao,Ruiyu Cao,Shukun Wei,Meng Tang,Lingyu Du,Hongyi Wu,Bin Wu, Yang Yu,Shuqing Wang,Maorong Wen,Bo OuYang,Regulation of PD-L1 through direct binding of cholesterol to CRAC motifs,Sci Adv2022 Aug 26.

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