Representative Publications----Institute of Biochemistry and Cell Biology, Shanghai Institute for Biological Sciences, CAS

Research

Xin Wang,Yueqiu Tan,Mofang Liu,Defective piRNA Processing and Azoospermia,NEW ENGL J MED2022 Apr 28.
Guixin Peng,Xueling Mao,Yating Cao,Shiying Yao,Qingrun Li,Xin Chen,Enduo Wang,Xiaolong Zhou,RNA granule-clustered mitochondrial aminoacyl-tRNA synthetases form multiple complexes with the potential to fine-tune tRNA aminoacylation,Nucleic Acids Res2022 Dec 12.
Youkui Huang,Baoqing Gao,Quan Meng,Liangzhong Yang,Xukai Ma,Hao Wu,Yuhang Pan,Li Yang,Dong Li,Lingling Chen,CRISPR-dCas13-tracing reveals transcriptional memory and limited mRNA export in developing zebrafish embryos,Genome Biol2023 Jan 19.
Tingting Yu,Yi Zhang,Wenqiang Zheng,Siqi Wu,Guoqiang Li,Yong Zhang,Niu Li,Ruen Yao,Pengfei Fang,Jian Wang,Xiaolong Zhou,Selective degradation of tRNASer(AGY) is the primary driver for mitochondrial seryl-tRNA synthetase-related disease,Nucleic Acids Res2022 Nov 9.
Shijie Tang,Yun Xue,Zhen Qin, Zhaoyuan Fang,Yihua Sun,Chongzhe Yuan,Yunjian Pan,Yue Zhao,Xinyuan Tong,Jian Zhang,Hsinyi Huang,Yuting Chen,Liang Hu,Dasong Huang,Ruiqi Wang,Weiguo Zou,Yuan Li,Roman K Thomas,Andrea Ventura,Kwok-Kin Wong,Haiquan Chen,Luonan Chen,Hongbin Ji,Counteracting lineage-specific transcription factor network finely tunes lung adeno-to-squamous transdifferentiation through remodeling tumor immune microenvironment,Natl Sci Rev2023 Feb 14.
Guoqing Cai,Yijun Qi,Ping Wei,Hong Gao,Chenqi Xu,Yun Zhao,Xiujuan Qu,Feng Yao,Weiwei Yang,IGFBP1 Sustains Cell Survival during Spatially-Confined Migration and Promotes Tumor Metastasis,Adv Sci2023 Jun 9.
Huan Zhao,Xiuzhen Huang,Zixin Liu,Liang Lai,Ruilin Sun,Ruling Shen,Yan Li,Lingjuan He,Wenjuan Pu,Zan Lv,Yi Li,Ximeng Han,Xiuxiu Liu,Bin Zhou,Use of a dual genetic system to decipher exocrine cell fate conversions in the adult pancreas,Cell Discov2023 Jan 3.
Zhaoyuan Fang,Xiangkun Han,Yueqing Chen,Xinyuan Tong,Yun Xue,Shun Yao,Shijie Tang,Yunjian Pan,Yihua Sun,Xue Wang,Yujuan Jin,Haiquan Chen,Liang Hu,Lijian Hui,Lin Li,Luonan Chen,Hongbin Ji,Oxidative stress-triggered Wnt signaling perturbation characterizes the tipping point of lung adeno-to-squamous transdifferentiation,Signal Transduct Target Ther2023 Jan 13.
Xin Wang,Anne Ramat,Martine Simonelig,Mofang Liu,Emerging roles and functional mechanisms of PIWI-interacting RNAs,Nat Rev Mol Cell Biol2022 Sep 14.
Xiuxiu Liu,Wendong Weng,Lingjuan He,Bin Zhou,Genetic recording of in vivo cell proliferation by ProTracer,Nat Protoc2023 Jun 2.
Rui Zhang,Xianteng Hou,Changwan Wang,Jiaxin Li,Junyan Zhu,Yingbo Jiang,Fajian Hou,The Endoplasmic Reticulum ATP13A1 is Essential for MAVS-Mediated Antiviral Innate Immunity,Adv Sci2022 Oct 10.
Qian Wang,Yunlei Cao,Lijuan Shen,Taoran Xiao,Ruiyu Cao,Shukun Wei,Meng Tang,Lingyu Du,Hongyi Wu,Bin Wu, Yang Yu,Shuqing Wang,Maorong Wen,Bo OuYang,Regulation of PD-L1 through direct binding of cholesterol to CRAC motifs,Sci Adv2022 Aug 26.
Shufei Ge,Mingliang Cai,Gang Pei,Frequency distribution of the hereditary Alzheimer's disease-related genes seems to fit Poisson distribution, why?,Cell Discov2022 Jul 28.
Yilin Xu,Jinglin Wang,Haozhen Ren,Hao Dai,Ying Zhou, Xiongzhao Ren,Yang Wang,Sisi Feng,Xiaogang Deng, Jiaying Wu,Tianlong Fu,Tengfei Nie,Haifeng He,Tongkun Wei,Bing Zhu,Lijian Hui,Bin Li,Jing Wang,Hongyan Wang,Luonan Chen,Xiaolei Shi,Xin Cheng,Human endoderm stem cells reverse inflammation-related acute liver failure through cystatin SN-mediated inhibition of interferon signaling,Cell Res2023 Jan 20.
Lin Shan,Guang Xu,Runwen Yao,Pengfei Luan,Youkui Huang,Peihong Zhang,Yuhang Pan,Lin Zhang,Xiang Gao,Ying Li,Shimeng Cao,Shuaixin Gao,Zhenghu Yang,Siqi Li,Liangzhong Yang,Ying Wang,Catharine C. L. Wong,Li Yu,Jinsong Li,Li Yang,Lingling Chen,Nucleolar URB1 ensures 3' ETS rRNA removal to prevent exosome surveillance,Nature2023 Mar 8.
Dongpeng Wang,Wei Wu#,Elsa Callen,Raphael Pavani,Nicholas Zolnerowich,Srikanth Kodali,Dali Zong,Nancy Wong,Santiago Noriega,William J Nathan,Gabriel Matos-Rodrigues,Raj Chari, Michael J Kruhlak,Ferenc Livak,Michael Ward, Keith Caldecott,Bruno Di Stefano,André Nussenzweig,Active DNA demethylation promotes cell fate specification and the DNA damage response,Science2022 Dec 1.
Lijun Wang,Xiuling You,Dengfeng Ruan,Rui Shao,Haiqiang Dai,Weiliang Shen,Guoliang Xu,Wanlu Liu,Weiguo Zou,TET enzymes regulate skeletal development through increasing chromatin accessibility of RUNX2 target genes,Nat Commun2022 Aug 11.
Siqi Li,Hao Wu,Lingling Chen,Screening circular RNAs with functional potential using the RfxCas13d/BSJ-gRNA system,Nat Protoc2022 Jul 13.
Sen Yang, Chunxia Liu, Yuting Guo, Guoqing Li, Dong Li, Xiumin Yan, Xueliang Zhu,Self-construction of actin networks through phase separation–induced abLIM1 condensates,P NATL ACAD SCI USA2022 Jul 11.
Wen Chen,Shuangfeng Chen,Chenghua Yan,Yaguang Zhang,Ronghua Zhang,Min Chen,Shufen Zhong,Weiguo Fan,Songling Zhu,Danyan Zhang,Xiao Lu,Jia Zhang,Yuying Huang,Lin Zhu,Xuezhen Li,Dawei Lv,Yadong Fu,Houkun Iv,Zhiyang Ling,Liyan Ma,Hai Jiang,Gang Long,Jinfang Zhu,Dong Wu,Bin Wu,Bing Sun,Allergen protease-activated stress granule assembly and gasdermin D fragmentation control interleukin-33 secretion,Nat Immunol2022 Jul 6.

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