Representative Publications----Institute of Biochemistry and Cell Biology, Shanghai Institute for Biological Sciences, CAS

Research

Xin Tang,Yifan Zhang,Guanchao Wang,Chunxiao Zhang,Fang Wang,Jiawen Shi,Tianlong Zhang,Jianping Ding,Molecular mechanism of S-adenosylmethionine sensing by SAMTOR in mTORC1 signaling,Sci Adv2022 Jul 1.
Wenjie Bao,Huayue Xing,Shiwei Cao,Xin Long,Haifeng Liu,Junwei Ma,Fan Guo,Zimu Deng,Xiaolong Liu,Neutrophils restrain sepsis associated coagulopathy via extracellular vesicles carrying superoxide dismutase 2 in a murine model of lipopolysaccharide induced sepsis,Nat Commun2022 Aug 6.
Junyan Kang,Ze Wen,Duo Pan,Yuhan Zhang,Qing Li,Ai Zhong,Xinghai Yu,Yichen Wu,Yu Chen,Xiangzheng Zhang,Pengcheng Kou,Junlan Geng,Yingyi Wang,Minmin Hua,Ruiting Zong,Biao Li,Huijuan Shi,Dangsheng Li,Xiangdong Fu,Jinsong Li,David L Nelson,Xuejiang Guo,Yu Zhou,Lantao Gou,Ying Huang,Mofang Liu,LLPS of FXR1 drives spermiogenesis by activating translation of stored mRNAs,Science2022 Aug 12.
Kuo Liu, Hengwei Jin, Muxue Tang, Shaohua Zhang, Xueying Tian, Mingjun Zhang, Ximeng Han, Xiuxiu Liu, Juan Tang, Wenjuan Pu, Yan Li, Lingjuan He, Zhongzhou Yang, Kathy O Lui, Bin Zhou,Lineage tracing clarifies the cellular origin of tissue-resident macrophages in the developing heart,J Cell Biol2022 Apr 28.
Xiaojing Li, Linlin Qi, Dan Yang, ShuJie Hao, Fang Zhang, Xingguo Zhu, Yue Sun, Chen Chen, Jing Ye, Jing Yang, Ling Zhao, Daniel M. Altmann, Shengbo Cao, Hongyan Wang, Bin Wei,Meningeal lymphatic vessels mediate neurotropic viral drainage from the central nervous system,Nat Neurosci2022 May 6.
Maoying Han, Zixin Liu, Lingjuan He, Xufeng Li, Lei Liu, Xiuzhen Huang, Mingjun Zhang, Yan Yan, Kathy O. Lui, Bin Zhou,Dual Genetic Lineage Tracing Reveals Capillary to Artery Formation in the Adult Heart,Circulation2022 Apr 11.
Xia Xie, Tingting Gan, Bing Rao, Weiwei Zhang, Rohit A Panchakshari, Dingpeng Yang, Xiong Ji, Yu Cao, Frederick W Alt, Feilong Meng, Jiazhi Hu,C-terminal deletion-induced condensation sequesters AID from IgH targets in immunodeficiency,EMBO J2022 Apr 26.
Fei Wang, Mengmeng Zhao, Boran Chang, Yilong Zhou, Xiangyang Wu, Mingtong Ma, Siyu Liu, Yajuan Cao, Mengge Zheng, Yifang Dang, Junfang Xu, Li Chen, Tianhao Liu, Fen Tang, Yefei Ren, Zhu Xu, Zhiyong Mao, Kai Huang, Minhua Luo, Jingsong Li, Haipeng Liu, Baoxue Ge,Cytoplasmic PARP1 links the genome instability to the inhibition of antiviral immunity through PARylating cGAS,Mol Cell2022 Apr 22.
Runtan Cheng, Lu Wang, Shenglong Le, Yifan Yang, Can Zhao, Xiangqi Zhang, Xin Yang, Ting Xu, Leiting Xu, Petri Wiklund, Jun Ge, Dajiang Lu, Chenhong Zhang, Luonan Chen, Sulin Cheng,A randomized controlled trial for response of microbiome network to exercise and diet intervention in patients with nonalcoholic fatty liver disease,Nat Commun2022 May 10.
Chenchen Guo, Ruijie Wan, Yayi He, Shu-Hai Lin, Jiayu Cao, Ying Qiu, Tengfei Zhang, Qiqi Zhao, Yujia Niu, Yujuan Jin, Hsin-Yi Huang, Xue Wang, Li Tan, Roman K. Thomas, Hua Zhang, Luonan Chen, Kwok-Kin Wong, Liang Hu, Hongbin Ji,Therapeutic targeting of the mevalonate-geranylgeranyl diphosphate pathway with statins overcomes chemotherapy resistance in small cell lung cancer,Nat Cancer2022 Apr 21.
Shaohua Zhang,Yan Li,Xiuzhen Huang,Kuo Liu,Qingdong Wang,Alex F Chen,Kun Sun,Kathy O Lui,Bin Zhou,Seamless Genetic Recording of Transiently Activated Mesenchymal Gene Expression in Endothelial Cells During Cardiac Fibrosis,Circulation2021 Nov 19.
Qing Zhang,Deqiang Yao,Bing Rao,Liyan Jian,Yang Chen,Kexin Hu,Ying Xia,Shaobai Li,Yafeng Shen,An Qin,Jie Zhao,Lu Zhou,Ming Lei,Xiancheng Jiang,Yu Cao,The structural basis for the phospholipid remodeling by lysophosphatidylcholine acyltransferase 3,Nat Commun2021 Nov 25.
Zhangcheng Chen,Luyu Fan,Huan Wang,Jing Yu,Dengyu Lu,Jianzhong Qi,Fen Nie,Zhipu Luo,Zhen Liu,Jianjun Cheng,Sheng Wang,Structure-based design of a novel third-generation antipsychotic drug lead with potential antidepressant properties,Nat Neurosci2021 Dec 9.
Qing Li,Jiansen Lu,Xidi Yin,Yunjian Chang,Chao Wang#,Meng Yan,Li Feng,Yanbo Cheng,Yun Gao,Beiying Xu,Yao Zhang,Yingyi Wang,Guizhong Cui,Luang Xu,Yidi Sun,Rong Zeng,Yixue Li,Naihe Jing,Guoliang Xu,Ligang Wu,Fuchou Tang,Jinsong Li,Base editing-mediated one-step inactivation of the Dnmt gene family reveals critical roles of DNA methylation during mouse gastrulation,Nat Commun2023 May 22.
Wencheng Zhu,Huiying Chu,Yajuan Zhang,Tianhang Luo,Hua Yu,Hongwen Zhu,Ye Liu,Hong Gao,Yun Zhao,Quanlin Li,Xiongjun Wang,Guohui Li,Weiwei Yang,Fructose-1,6-bisphosphatase 1 dephosphorylates IκBα and suppresses colorectal tumorigenesis,Cell Res2023 Jan 16.
Lingling Chen,Albrecht Bindereif,Irene Bozzoni,Howard Y. Chang,A. Gregory Matera,Myriam Gorospe,Thomas B. Hansen,J？rgen Kjems,Xukai Ma,Jun Wei Pek,Nikolaus Rajewsky,Julia Salzman,Jeremy E. Wilusz,Li Yang,Fangqing Zhao,A guide to naming eukaryotic circular RNAs,Nat Cell Biol2023 Jan 19.
Kuo Liu,Muxue Tang,Wei Xu,Xinfeng Meng,Hengwei Jin,Maoying Han,Jing Pu,Yutang Li,Fanke Jiao,Ruilin Sun,Ruling Shen,Kathy O Lui,Lu Lu,Bin Zhou,An inducible hACE2 transgenic mouse model recapitulates SARS-CoV-2 infection and pathogenesis in vivo,Proc Natl Acad Sci U S A2023 Jun 12.
Zhishuo Wang,Chenghua Yan,Qizhen Du,Yuying Huang,Xuezhen Li,Dan Zeng,Ruizhi Mao,Rama Krishna Gurram,Shipeng Cheng,Wangpeng Gu,Lin Zhu,Weiguo Fan,Liyan Ma,Zhiyang Ling,Ju Qiu,Dangsheng Li,Enmei Liu,Yaguang Zhang,Yiru Fang,Jinfang Zhu,Bing Sun,HTR2A agonists play a therapeutic role by restricting ILC2 activation in papain-induced lung inflammation,Cell Mol Immunol2023 Feb 24.
Yifan Wang,Qiang Zheng,Zhen Sun,Chenhua Wang,Jin Cen,Xinjie Zhang,Yan Jin,Baihua Wu,Tingting Yan, Ziyuan Wang,Qiuxia Gu,Xingyu Lv,Junjie Nan,Zhongyu Wu,Wenbin Sun,Guoyu Pan,Ludi Zhang,Lijian Hui,Xiujun Cai,Reversal of liver failure using a bioartificial liver device implanted with clinical-grade human induced hepatocytes,Cell Stem Cell2023 Apr 13.
Xinyang Song,Haohao Zhang,Yanbo Zhang,Byoungsook Goh,Bin Bao,Suelen S. Mello,Ximei Sun,Wen Zheng,Francesca S. Gazzaniga,Meng Wu,Fangfang Qu, Qiangzong Yin,Michael S. Gilmore,Sungwhan F. Oh, Dennis L. Kasper,Gut microbial fatty acid isomerization modulates intraepithelial T cells,Nature2023 Jun 28.

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