Representative Publications----Institute of Biochemistry and Cell Biology, Shanghai Institute for Biological Sciences, CAS

Research

Runtan Cheng, Lu Wang, Shenglong Le, Yifan Yang, Can Zhao, Xiangqi Zhang, Xin Yang, Ting Xu, Leiting Xu, Petri Wiklund, Jun Ge, Dajiang Lu, Chenhong Zhang, Luonan Chen, Sulin Cheng,A randomized controlled trial for response of microbiome network to exercise and diet intervention in patients with nonalcoholic fatty liver disease,Nat Commun2022 May 10.
Chenchen Guo, Ruijie Wan, Yayi He, Shu-Hai Lin, Jiayu Cao, Ying Qiu, Tengfei Zhang, Qiqi Zhao, Yujia Niu, Yujuan Jin, Hsin-Yi Huang, Xue Wang, Li Tan, Roman K. Thomas, Hua Zhang, Luonan Chen, Kwok-Kin Wong, Liang Hu, Hongbin Ji,Therapeutic targeting of the mevalonate-geranylgeranyl diphosphate pathway with statins overcomes chemotherapy resistance in small cell lung cancer,Nat Cancer2022 Apr 21.
Shaohua Zhang,Yan Li,Xiuzhen Huang,Kuo Liu,Qingdong Wang,Alex F Chen,Kun Sun,Kathy O Lui,Bin Zhou,Seamless Genetic Recording of Transiently Activated Mesenchymal Gene Expression in Endothelial Cells During Cardiac Fibrosis,Circulation2021 Nov 19.
Qing Zhang,Deqiang Yao,Bing Rao,Liyan Jian,Yang Chen,Kexin Hu,Ying Xia,Shaobai Li,Yafeng Shen,An Qin,Jie Zhao,Lu Zhou,Ming Lei,Xiancheng Jiang,Yu Cao,The structural basis for the phospholipid remodeling by lysophosphatidylcholine acyltransferase 3,Nat Commun2021 Nov 25.
Zhangcheng Chen,Luyu Fan,Huan Wang,Jing Yu,Dengyu Lu,Jianzhong Qi,Fen Nie,Zhipu Luo,Zhen Liu,Jianjun Cheng,Sheng Wang,Structure-based design of a novel third-generation antipsychotic drug lead with potential antidepressant properties,Nat Neurosci2021 Dec 9.
Qing Li,Jiansen Lu,Xidi Yin,Yunjian Chang,Chao Wang#,Meng Yan,Li Feng,Yanbo Cheng,Yun Gao,Beiying Xu,Yao Zhang,Yingyi Wang,Guizhong Cui,Luang Xu,Yidi Sun,Rong Zeng,Yixue Li,Naihe Jing,Guoliang Xu,Ligang Wu,Fuchou Tang,Jinsong Li,Base editing-mediated one-step inactivation of the Dnmt gene family reveals critical roles of DNA methylation during mouse gastrulation,Nat Commun2023 May 22.
Wencheng Zhu,Huiying Chu,Yajuan Zhang,Tianhang Luo,Hua Yu,Hongwen Zhu,Ye Liu,Hong Gao,Yun Zhao,Quanlin Li,Xiongjun Wang,Guohui Li,Weiwei Yang,Fructose-1,6-bisphosphatase 1 dephosphorylates IκBα and suppresses colorectal tumorigenesis,Cell Res2023 Jan 16.
Lingling Chen,Albrecht Bindereif,Irene Bozzoni,Howard Y. Chang,A. Gregory Matera,Myriam Gorospe,Thomas B. Hansen,J？rgen Kjems,Xukai Ma,Jun Wei Pek,Nikolaus Rajewsky,Julia Salzman,Jeremy E. Wilusz,Li Yang,Fangqing Zhao,A guide to naming eukaryotic circular RNAs,Nat Cell Biol2023 Jan 19.
Kuo Liu,Muxue Tang,Wei Xu,Xinfeng Meng,Hengwei Jin,Maoying Han,Jing Pu,Yutang Li,Fanke Jiao,Ruilin Sun,Ruling Shen,Kathy O Lui,Lu Lu,Bin Zhou,An inducible hACE2 transgenic mouse model recapitulates SARS-CoV-2 infection and pathogenesis in vivo,Proc Natl Acad Sci U S A2023 Jun 12.
Zhishuo Wang,Chenghua Yan,Qizhen Du,Yuying Huang,Xuezhen Li,Dan Zeng,Ruizhi Mao,Rama Krishna Gurram,Shipeng Cheng,Wangpeng Gu,Lin Zhu,Weiguo Fan,Liyan Ma,Zhiyang Ling,Ju Qiu,Dangsheng Li,Enmei Liu,Yaguang Zhang,Yiru Fang,Jinfang Zhu,Bing Sun,HTR2A agonists play a therapeutic role by restricting ILC2 activation in papain-induced lung inflammation,Cell Mol Immunol2023 Feb 24.
Yifan Wang,Qiang Zheng,Zhen Sun,Chenhua Wang,Jin Cen,Xinjie Zhang,Yan Jin,Baihua Wu,Tingting Yan, Ziyuan Wang,Qiuxia Gu,Xingyu Lv,Junjie Nan,Zhongyu Wu,Wenbin Sun,Guoyu Pan,Ludi Zhang,Lijian Hui,Xiujun Cai,Reversal of liver failure using a bioartificial liver device implanted with clinical-grade human induced hepatocytes,Cell Stem Cell2023 Apr 13.
Xinyang Song,Haohao Zhang,Yanbo Zhang,Byoungsook Goh,Bin Bao,Suelen S. Mello,Ximei Sun,Wen Zheng,Francesca S. Gazzaniga,Meng Wu,Fangfang Qu, Qiangzong Yin,Michael S. Gilmore,Sungwhan F. Oh, Dennis L. Kasper,Gut microbial fatty acid isomerization modulates intraepithelial T cells,Nature2023 Jun 28.
Wenjuan Pu,Huan Zhu,Mingjun Zhang,Monika Pikiolek,Caner Ercan,Jie Li,Xiuzhen Huang,Ximeng Han,Zhenqian Zhang,Zan Lv,Yan Li,Kuo Liu,Lingjuan He,Xiuxiu Liu,Markus H. Heim,Luigi M. Terracciano,Jan S. Tchorz,Bin Zhou,Bipotent transitional liver progenitor cells contribute to liver regeneration,Nat Genet2023 Mar 13.
Yuang Wang,Zhen Qu,Yi Fang,Yulong Chen,Jiayin Peng,Jiawen Song,Jinsong Li,Jiantao Shi,Jinqiu Zhou,Yun Zhao,Chromosome territory reorganization through artificial chromosome fusion is compatible with cell fate determination and mouse development,Cell Discov2023 Jan 24.
Qinqin Cui,Hongyun Bi,Zhanyun Lv,Qigui Wu,Jianfeng Hua,Bokai Gu,Chanjuan Huo,Mingmin Tang,Yanqin Chen,Chongjiu Chen,Sihan Chen,Xinrui Zhang,Zhangrui Wu,Zhengkai Lao,Nengyin Sheng,Chengyong Shen,Yongdeng Zhang,Zhiying Wu,Zhigang Jin,Peiguo Yang,Huaqing Liu,Jinsong Li,Ge Bai,Diverse CMT2 neuropathies are linked to aberrant G3BP interactions in stress granules,Cell2023 Feb 3.
Mingjun Zhang,Wenjuan Pu,Jie Li,Maoying Han,Ximeng Han,Zhenqian Zhang,Zan Lv,Nicola Smart,Lixin Wang, Bin Zhou,Coronary vessels contribute to de novo endocardial cells in the endocardium-depleted heart,Cell Discov2023 Jan 10.
Fang Zhang,Baokai Zhang,Huihua Ding,Xiangyue Li,Xilin Wang,Xiaomin Zhang,Qiaojie Liu,Qiuyun Feng,Mingshun Han,Longlong Chen,Linlin Qi,Dan Yang,Xiaojing Li,Xingguo Zhu,Qi Zhao,Jiaqian Qiu,Zhengjiang Zhu,Huiru Tang,Nan Shen,Hongyan Wang,Bin We,The Oxysterol Receptor EBI2 Links Innate and Adaptive Immunity to Limit IFN Response and Systemic Lupus Erythematosus,Adv Sci2023 Jul 19.
Chao Zhang,Caixuan Liu,Jinping Shi,Yalei Wang,Cong Xu,Xiaohua Ye,Qingwei Liu,Xue Li,Weihua Qiao,Yannan Yin,Yao Cong,Zhong Huang,Molecular mechanism of antibody neutralization of coxsackievirus A16,Nat Commun2022 Dec 21.
Yaogan Luo,Liang Sun,Qingqing Wu,Boyu Song,Yanpu Wu,Xiaowei Yang,Puchen Zhou,Zhenhua Niu,He Zheng,Huaixing Li,Weiqiong Gu,Jiqiu Wang,Guang Ning,Rong Zeng,Xu Lin,Diet-Related Lipidomic Signatures and Changed Type 2 Diabetes Risk in a Randomized Controlled Feeding Study With Mediterranean Diet and Traditional Chinese or Transitional Diets,Diabetes Care2023 Jul 18.
Yanyan Wang,Senxin Zhang,Xinrui Yang,Joyce K. Hwang,Chuanzong Zhan,Chaoyang Lian,Chong Wang,Tuantuan Gui,Binbin Wang,Xia Xie,Pengfei Dai,Lu Zhang,Ying Tian,Huizhi Zhang,Chong Han,Yanni Cai,Qian Hao,Xiaofei Ye,Xiaojing Liu,Jiaquan Liu,Zhiwei Cao,Shaohui Huang,Jie Song,Qiang Pan-Hammarstrom,Yaofeng Zhao,Frederick W. Alt,Xiaoqi Zheng,Lintai Da,Leng-Siew Yeap,Feilong Meng,Mesoscale DNA feature in antibody-coding sequence facilitates somatic hypermutation,Cell2023 Apr 24.

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