Representative Publications----Institute of Biochemistry and Cell Biology, Shanghai Institute for Biological Sciences, CAS

Research

uo Liu,Hengwei Jin,Shaohua Zhang,Muxue Tang,Xinfeng Meng,Yan Li,Wenjuan Pu,Kathy O Lui,Bin Zhou,Intercellular genetic tracing of cardiac endothelium in the developing heart,Dev Cell2023 Jun 21.
Yanyan Wang, Senxin Zhang, Xiaoqi Zheng, Leng-Siew Yeap, Fei-Long Meng,A high-throughput protocol for deamination of long single-stranded DNA and oligo pools containing complex sequences,STAR Protoc2023 Sep 23.
Shan Jin, Xingchen Chen, Jun Yang, Jianping Ding,Lactate dehydrogenase D is a general dehydrogenase for D-2-hydroxyacids and is associated with D-lactic acidosis,Nat Commun2023 Oct 20.
Xiaowen Yang,Xiaopeng Han,Chong Han,James London,Richard Fishel,Jiaquan Liu,MutS functions as a clamp loader by positioning MutL on the DNA during mismatch repair,Nat Commun2022 Oct 3.
Yanjing Li,Lijie Zhao,Yuebin Zhang,Ping Wu,Ying Xu, Jun Mencius,Yongxin Zheng,Xiaoman Wang,Wancheng Xu, Naizhe Huang,Xianwen Ye,Ming Lei,Pan Shi,Changlin Tian,Chao Peng,Guohui Li,Zhijun Liu,Shu Quan,Yong Chen,Structural basis for product specificities of MLL family methyltransferases,Mol Cell2022 Sep 14.
Xiaoyu Sun,Chunyan Yi,Yuanfei Zhu,Longfei Ding,Shuai Xia,Xingchen Chen,Mu Liu,Chenjian Gu,Xiao Lu,Yadong Fu,Shuangfeng Chen,Tianlong Zhang,Yaguang Zhang,Zhuo Yang,Liyan Ma,Wangpeng Gu,Gaowei Hu,Shujuan Du,Renhong Yan,Weihui Fu,Songhua Yuan,Chenli Qiu,Chen Zhao,Xiaoyan Zhang,Yonghui He,Aidong Qu,Xu Zhou,Xiuling Li,Gary Wong,Qiang Deng,Qiang Zhou,Hongzhou Lu,Zhiyang Ling,Jianping Ding,Lu Lu,Jianqing Xu,Youhua Xie,Bing Sun,Neutralization mechanism of a human antibody with pan-coronavirus reactivity including SARS-CoV-2,Nat Microbiol2022 Jun 30.
Xin Tang,Yifan Zhang,Guanchao Wang,Chunxiao Zhang,Fang Wang,Jiawen Shi,Tianlong Zhang,Jianping Ding,Molecular mechanism of S-adenosylmethionine sensing by SAMTOR in mTORC1 signaling,Sci Adv2022 Jul 1.
Wenjie Bao,Huayue Xing,Shiwei Cao,Xin Long,Haifeng Liu,Junwei Ma,Fan Guo,Zimu Deng,Xiaolong Liu,Neutrophils restrain sepsis associated coagulopathy via extracellular vesicles carrying superoxide dismutase 2 in a murine model of lipopolysaccharide induced sepsis,Nat Commun2022 Aug 6.
Junyan Kang,Ze Wen,Duo Pan,Yuhan Zhang,Qing Li,Ai Zhong,Xinghai Yu,Yichen Wu,Yu Chen,Xiangzheng Zhang,Pengcheng Kou,Junlan Geng,Yingyi Wang,Minmin Hua,Ruiting Zong,Biao Li,Huijuan Shi,Dangsheng Li,Xiangdong Fu,Jinsong Li,David L Nelson,Xuejiang Guo,Yu Zhou,Lantao Gou,Ying Huang,Mofang Liu,LLPS of FXR1 drives spermiogenesis by activating translation of stored mRNAs,Science2022 Aug 12.
Kuo Liu, Hengwei Jin, Muxue Tang, Shaohua Zhang, Xueying Tian, Mingjun Zhang, Ximeng Han, Xiuxiu Liu, Juan Tang, Wenjuan Pu, Yan Li, Lingjuan He, Zhongzhou Yang, Kathy O Lui, Bin Zhou,Lineage tracing clarifies the cellular origin of tissue-resident macrophages in the developing heart,J Cell Biol2022 Apr 28.
Xiaojing Li, Linlin Qi, Dan Yang, ShuJie Hao, Fang Zhang, Xingguo Zhu, Yue Sun, Chen Chen, Jing Ye, Jing Yang, Ling Zhao, Daniel M. Altmann, Shengbo Cao, Hongyan Wang, Bin Wei,Meningeal lymphatic vessels mediate neurotropic viral drainage from the central nervous system,Nat Neurosci2022 May 6.
Maoying Han, Zixin Liu, Lingjuan He, Xufeng Li, Lei Liu, Xiuzhen Huang, Mingjun Zhang, Yan Yan, Kathy O. Lui, Bin Zhou,Dual Genetic Lineage Tracing Reveals Capillary to Artery Formation in the Adult Heart,Circulation2022 Apr 11.
Xia Xie, Tingting Gan, Bing Rao, Weiwei Zhang, Rohit A Panchakshari, Dingpeng Yang, Xiong Ji, Yu Cao, Frederick W Alt, Feilong Meng, Jiazhi Hu,C-terminal deletion-induced condensation sequesters AID from IgH targets in immunodeficiency,EMBO J2022 Apr 26.
Fei Wang, Mengmeng Zhao, Boran Chang, Yilong Zhou, Xiangyang Wu, Mingtong Ma, Siyu Liu, Yajuan Cao, Mengge Zheng, Yifang Dang, Junfang Xu, Li Chen, Tianhao Liu, Fen Tang, Yefei Ren, Zhu Xu, Zhiyong Mao, Kai Huang, Minhua Luo, Jingsong Li, Haipeng Liu, Baoxue Ge,Cytoplasmic PARP1 links the genome instability to the inhibition of antiviral immunity through PARylating cGAS,Mol Cell2022 Apr 22.
Runtan Cheng, Lu Wang, Shenglong Le, Yifan Yang, Can Zhao, Xiangqi Zhang, Xin Yang, Ting Xu, Leiting Xu, Petri Wiklund, Jun Ge, Dajiang Lu, Chenhong Zhang, Luonan Chen, Sulin Cheng,A randomized controlled trial for response of microbiome network to exercise and diet intervention in patients with nonalcoholic fatty liver disease,Nat Commun2022 May 10.
Chenchen Guo, Ruijie Wan, Yayi He, Shu-Hai Lin, Jiayu Cao, Ying Qiu, Tengfei Zhang, Qiqi Zhao, Yujia Niu, Yujuan Jin, Hsin-Yi Huang, Xue Wang, Li Tan, Roman K. Thomas, Hua Zhang, Luonan Chen, Kwok-Kin Wong, Liang Hu, Hongbin Ji,Therapeutic targeting of the mevalonate-geranylgeranyl diphosphate pathway with statins overcomes chemotherapy resistance in small cell lung cancer,Nat Cancer2022 Apr 21.
Shaohua Zhang,Yan Li,Xiuzhen Huang,Kuo Liu,Qingdong Wang,Alex F Chen,Kun Sun,Kathy O Lui,Bin Zhou,Seamless Genetic Recording of Transiently Activated Mesenchymal Gene Expression in Endothelial Cells During Cardiac Fibrosis,Circulation2021 Nov 19.
Qing Zhang,Deqiang Yao,Bing Rao,Liyan Jian,Yang Chen,Kexin Hu,Ying Xia,Shaobai Li,Yafeng Shen,An Qin,Jie Zhao,Lu Zhou,Ming Lei,Xiancheng Jiang,Yu Cao,The structural basis for the phospholipid remodeling by lysophosphatidylcholine acyltransferase 3,Nat Commun2021 Nov 25.
Zhangcheng Chen,Luyu Fan,Huan Wang,Jing Yu,Dengyu Lu,Jianzhong Qi,Fen Nie,Zhipu Luo,Zhen Liu,Jianjun Cheng,Sheng Wang,Structure-based design of a novel third-generation antipsychotic drug lead with potential antidepressant properties,Nat Neurosci2021 Dec 9.
Qing Li,Jiansen Lu,Xidi Yin,Yunjian Chang,Chao Wang#,Meng Yan,Li Feng,Yanbo Cheng,Yun Gao,Beiying Xu,Yao Zhang,Yingyi Wang,Guizhong Cui,Luang Xu,Yidi Sun,Rong Zeng,Yixue Li,Naihe Jing,Guoliang Xu,Ligang Wu,Fuchou Tang,Jinsong Li,Base editing-mediated one-step inactivation of the Dnmt gene family reveals critical roles of DNA methylation during mouse gastrulation,Nat Commun2023 May 22.

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