Representative Publications----Institute of Biochemistry and Cell Biology, Shanghai Institute for Biological Sciences, CAS

Research

Mengwen Huang,Xingchao Pan,Xinling Wang,Qingfei Ren,Bei Tong,Xianchi Dong,Gaoxiang Ge,Lu Lu,Shibo Jiang,Jianfeng Chen,Lymphocyte integrins mediate entry and dysregulation of T cells by SARS-CoV-2,Signal Transduct Target Ther2023 Feb 27.
Shaohua Zhang,Qianyu Zhang,Zixin Liu,Kuo Liu,Lingjuan He,Kathy O Lui,Lixin Wang,Bin Zhou,Genetic dissection of intercellular interactions in vivo by membrane-permeable protein,P NATL ACAD SCI USA2022 Dec 27.
Songling Zhu,Shufen Zhong,Kebin Cheng,Lisha Zhang,Jiuwu Bai,Zu Cao,Su Wang,Wen Chen,Shipeng Cheng,Liyan Ma,Zhiyang Ling,Yuying Huang,Wangpeng Gu,Xiaoyu Sun,Chunyan Yi,Meng Zhao,Shuo Liang,Jinfu Xu,Bing Sun,Yaguang Zhang,itamin B6 regulates IL-33 homeostasis to alleviate type 2 inflammation,Cell Mol Immunol2023 May 23.
Xun Wang,Xing He,Shujun Jiang,Zhangfan Fu,Shuai Jiang, Xiaoyu Zhao, Chaoyue Zhao, Yaning Li,Dianfan Li,Wenhong Zhang,Jingwen Ai,Yanliang Zhang,Chenqi Xu,Pengfei Wang,Limited enhancement of antibody and B‐cell responses to prototype booster vaccination following SARS‐CoV‐2 Delta breakthrough infection,J Med Virol2023 Feb 1.
Xuan Xie,Shaogang Wang,Mingyi Li,Lei Diao,Xingyu Pan,Jijun Chen,Weiguo Zou,Xu Zhang,Wenfeng Feng,Lan Bao,α-TubK40me3 is required for neuronal polarization and migration by promoting microtubule formation,Nat Commun2021 Jul 05.
Youhua Zhang,Ruting Xie,Hailong Zhang,Yajuan Zheng,Changdong Lin,Lei Yang,Mengwen Huang,Man Li,Feifei Song,Ling Lu,Muqing Yang,Ying Liu,Qing Wei,Jiyu Li,Jianfeng Chen,Integrin β7 inhibits colorectal cancer pathogenesis via maintaining anti-tumor immunity,Cancer Immunol Res2021 Jun 15.
Samantha Sayers，Li Li，Edison Ong，Shunzhou Deng，Guanghua Fu，Yu Lin，Brian Yang，Shelley Zhang，henzong Fa，Bin Zhao，Zuoshuang Xiang，Yongqing Li，Xingming Zhao，Michal A Olszewski，Luonan Chen,Yongqun He,Victors: a web-based knowledge base of virulence factors in human and animal pathogens,Nucleic Acids ResNucleic Acids Res
Jinwei Zhu,Qingqing Zhou,Yitian Xia,Lin Lin,Jianchao Li,Mengjuan Peng,Rongguang Zhang,Mingjie Zhang,GIT/PIX Condensates Are Modular and Ideal for Distinct Compartmentalized Cell Signaling,Mol Cell2020 Aug 10.
Shanshan Wang,Xinyu Thomas Tang,Minghui Lin,Jia Yuan,Yi Jacky Peng,Xiujuan Yin,GuoGuo Shang,Gaoxiang Ge,Zhenggang Ren,Bo O Zhou,Perivenous stellate cells are the main source of myofibroblasts and cancer-associated-fibroblasts formed after chronic liver injuries,Hepatology2021 Apr 5.
Jinhuan Chen,Yifan Wang,Cong Xu,Kaijian Chen,Qiaoyu Zhao,Shutian Wang,Yue Yin,Chao Peng,Zhanyu Ding,Yao Cong,Cryo-EM of mammalian PA28αβ-iCP immunoproteasome reveals a distinct mechanism of proteasome activation by PA28αβ,Nat Commun2021 Feb 2.
Yincong Zhang,Xiaona Zhang,Yumin Dai,Mengjiao Song,Yifei Zhou,Jun Zhou,Xiumin Yan,Yidong Shen,The decrease of intraflagellar transport impairs sensory perception and metabolism in ageing,Nat Commun2021 Mar 19.
Lingjuan He,Wenjuan Pu,Xiuxiu Liu,Zhenqian Zhang,Maoying Han,Yi Li,Xiuzhen Huang,Ximeng Han,Yan Li,Kuo Liu,Mengyang Shi,Liang Lai,Ruilin Sun,Qingdong Wang,Yong Ji,Jan S.Tchorz,Bin Zhou,Proliferation tracing reveals regional hepatocyte generation in liver homeostasis and repair,Science2021 Feb 26.
Beibei Wang,Tianlong Zhang,Jun Yin,You Yu,Wenhao Xu,Jianping Ding,Dinshaw J.Pate,Hui Yang,Structural basis for self-cleavage prevention by tag:anti-tag pairing complementarity in Type VI CRISPR-Cas systems,Mol Cell2021 Jan 21.
Guixin Peng,Yong Zhang,Qinqin Wang,Qingrun Li,Hong Xu,Enduo Wang,Xiaolong Zhou,The human tRNA taurine modification enzyme GTPBP3 is an active GTPase linked to mitochondrial diseases,Nucleic Acids Res2021 Feb 22.
Cong Xu,Yanxing Wang,Caixuan Liu,Chao Zhang,Wenyu Han,Xiaoyu Hong,Yifan Wang,Qin Hong,Shutian Wang,Qiaoyu Zhao,Yalei Wang,Yong Yang,Kaijian Chen,Wei Zheng,Liangliang Kong,Fangfang Wang,Qinyu Zuo,Zhong Huang,Yao Cong,Conformational dynamics of SARS-CoV-2 trimeric spike glycoprotein in complex with receptor ACE2 revealed by cryo-EM,Sci Adv2020 Dec 4.
Shichao Duan,Hao Li,Yirong Zhang,Suming Yang,Yawen Chen,Benhua Qiu,Cheng Huang,Juan Wang,Jinsong Li,Xueliang Zhu,Xiumin Yan,Rabl2 GTP hydrolysis licenses BBSome-mediated export to fine-tune ciliary signaling,EMBO J2020 Nov 26.
Heng Feng,Wenhui Xing,Yujiao Han,Jun Sun,Mingxiang Kong,Bo Gao,Yang Yang,Zi Yin,Xiao Chen,Yun Zhao,Qing Bi,Weiguo Zou,Tendon-derived cathepsin K-expressing progenitor cells activate Hedgehog signaling to drive heterotopic ossification,J Clin Invest2020 Aug 27.
Alessandro Cicconi,Rekha Rai,Xuexue Xiong,Cayla Broton,Amer Al-Hiyasat,Chunyi Hu,Siying Dong,Wenqi Sun,Jennifer Garbarino,Ranjit S Bindra, Carl Schildkraut,Yong Chen,Sandy Chang,Microcephalin 1/BRIT1-TRF2 interaction promotes telomere replication and repair, linking telomere dysfunction to primary microcephaly,Nat Commun2020 Nov 17.
Jingjing Wang,Meng Wu,Zhangcheng Chen,Lijie Wu,Tian Wang,Dongmei Cao,Huan Wang,Shenhui Liu,Yueming Xu,Fei Li,Junlin Liu,Na Chen,Suwen Zhao,Jianjun Cheng,Sheng Wang,Tian Hua,The unconventional activation of the muscarinic acetylcholine receptor M4R by diverse ligands,Nat Commun2022 May 23.
Shichao Huang,Zhen Zhang,Junwei Cao,Yongchun Yu,Gang Pei,Chimeric cerebral organoids reveal the essentials of neuronal and astrocytic APOE4 for Alzheimer’s tau pathology,SIGNAL TRANSDUCT TAR2022 Jun 13.

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